Search results for "TG"

showing 10 items of 2275 documents

Histopathology of ameloblastoma of the jaws; some critical observations based on a 40 years single institution experience

2011

The aim of the present study is to examine all cases of intraosseous benign ameloblastomas treated between 1970 and 2010 in a single institution and to look for a possible correlation between the histopathological aspects and the demographical and clinical parameters, as well as the treatment outcome. The data of a total number of 44 patients were retrieved from the records. Nine patients were excluded because of doubt about the correct diagnosis (8 patients) or because of an extra-osseous presentation (1 patient). No statistically significant differences were found between the histopathological (sub)types of ameloblastomas and the demographical and clinical parameters, nor between the hist…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentEnucleationAmeloblastomaYoung AdultSDG 3 - Good Health and Well-beingmedicineHumansClinical significanceYoung adultSingle institutionAmeloblastomaChildGeneral DentistryAgedOral Medicine and Pathologybusiness.industryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseJaw NeoplasmsSurgeryOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASRecurrent lesion/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSurgeryHistopathologyResearch-ArticleFemaleRadiologyIntraosseous Ameloblastomabusiness
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The epidemiology, treatment, and complication of ameloblastoma in East-Indonesia

2018

Background Ameloblastoma is a neoplasm classified as a benign epithelial odontogenic tumor of the jaws, grow slowly and are locally invasive. The aim of the present study was to investigate the incidence, treatment, and complication of patients with ameloblastoma in East-Indonesia during six years retrospective study. Material and Methods This retrospective study included 84 patients who were diagnosed with ameloblastoma from 2011 to 2016. There were 56 patients with treatment data available. Data from each patient, including gender, age, histologic type, the size of the tumor, radiologic form, tumor location, type of treatment, and complication were reviewed and analyzed retrospectively. R…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentUnicystic AmeloblastomaAmeloblastomaYoung Adult03 medical and health sciencesFollicular Ameloblastoma0302 clinical medicineSDG 3 - Good Health and Well-beingEpidemiologymedicineHumansChildAmeloblastomaGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologybusiness.industryIncidenceResearchIncidence (epidemiology)Odontogenic tumorRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseSurgeryOtorhinolaryngologyIndonesiaChild Preschool030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICAS/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleSurgeryComplicationbusinessMedicina oral patologia oral y cirugia bucal
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Multiple periscope and chimney grafts to treat ruptured thoracoabdominal and pararenal aortic aneurysms

2011

Purpose: To report midterm outcomes after urgent endovascular repair of ruptured pararenal or thoracoabdominal aortic aneurysms using multiple periscope and chimney grafts to preserve renovisceral branch perfusion and facilitate aneurysm exclusion. Methods: Nine consecutive men (mean age 72614 years, range 40–88) presenting with ruptured thoracoabdominal (n56), pararenal (n52), or infrarenal (n51) aortic aneurysm underwent urgent endovascular repair with at least 1 periscope graft delivered via a transfemoral access; chimney grafts were installed from an axillary access. In all, 17 periscope and 7 chimney grafts were used to reperfuse 11 renal and 13 visceral arteries in the 9 patients. The…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentAortic RuptureLess invasive610 Medicine & healthRuptured Aortic AneurysmProsthesis DesignEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortography2705 Cardiology and Cardiovascular Medicinelaw.inventionBlood Vessel Prosthesis ImplantationlawmedicineHumans2741 Radiology Nuclear Medicine and ImagingRadiology Nuclear Medicine and imagingChimneyAgedRetrospective Studiesendodebranching renovisceral arteries chimney graft periscope graft stentgraft endograft ruptured aortic aneurysm ruptured thoracoabdominal aortic aneurysm ruptured pararenal aortic aneurysm ruptured AAA endovascular aneurysm repairAged 80 and overAortic Aneurysm Thoracicbusiness.industry10042 Clinic for Diagnostic and Interventional RadiologyEndovascular ProceduresChimney graftBlood flowMiddle AgedSurgeryBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgeryTreatment Outcomecardiovascular systemSurgeryFemaleStentsRadiologyPeriscopeCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedAortic Aneurysm Abdominal
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Neuromuscular control during gait in people with haemophilic arthropathy

2019

Introduction: Effects of haemophilic arthropathy on neuromuscular control during gait are currently unknown. Aims: (a) To assess how haemophilic arthropathy affects the complexity of neuromuscular control during gait; (b) To investigate the relationship between complexity of neuromuscular control and joint impairment. Methods: Thirteen control subjects (CG) walked overground at their preferred and a slow velocity and thirteen people with haemophilic arthropathy (PWHA) walking at their preferred velocity. Surface electromyography (EMG) was collected from eleven leg muscles. Electromyography variance explained by muscle synergies (sets of co-activated muscles that can be recruited by a single…

AdultMalemedicine.medical_specialtyhaemophiliaElectromyographyWalking030204 cardiovascular system & hematologyKnee Jointsurface electromyographyHaemophiliaHemophilia AHemophilia BSeverity of Illness Indexknee joint03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationSDG 3 - Good Health and Well-beingneuromuscular controlmedicineCluster AnalysisHumansankle jointMuscle SkeletalGaitGenetics (clinical)medicine.diagnostic_testbusiness.industryElectromyographymuscle synergyMotor controlHematologyGeneral MedicineExplained variationmedicine.diseaseGaitmedicine.anatomical_structureCase-Control Studies/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingAnkleNeuromuscular controlJoint Diseasesbusinesshuman activities030215 immunology
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The influence of organizational factors on road transport safety

2018

Road transport safety is a major concern across Europe due to the human and socio-economic costs associated with work-related traffic accidents. Traditional approaches have adopted regulatory and technical measures to prevent road accidents leaving aside the organizational factors that might contribute to road transport safety. However, contemporary sociotechnical systems theory acknowledges the need to take into account organizational factors. This study adopts a sociotechnical approach and it examines the relationship between a number of organizational factors (organizational learning and training) and road traffic accidents in the organizations under study. Our sample was composed of 107…

AdultSociotechnical systemHealth Toxicology and MutagenesisControl variablelcsh:MedicinePoison controlTransportationSample (statistics)ArticleOccupational safety and healthorganizational learning0502 economics and businessInjury preventionHumansLearningTrainingroad transport safetyRoad transport safetysociotechnical approachOrganizations050210 logistics & transportationtrainingPsicologia socialbusiness.industrySeguretat viàrialcsh:R05 social sciencesAccidents TrafficOrganizational learningPublic Health Environmental and Occupational HealthHuman factors and ergonomicsTraffic safetyEnvironmental economicsAprenentatge organitzatiuOrganizational CultureSociotechnical approachSpainOrganizational learningSeguridad vialAprendizaje organizacionalSafetybusiness050203 business & management
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Myofibroblasts Are Evidence of Chronic Tissue Microtrauma at the Endometrial-Myometrial Junctional Zone in Uteri With Adenomyosis.

2017

Background Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation of basal endometrial fragments into the myometrium. There, a metaplasia (mediated by transforming growth factor β1 [TGFβ1] and connective tissue growth factor [CTGF]) occurs and AM lesions develop. The abundance of myofibroblasts in a tissue hallmarks metaplasia and points to a tissue microtrauma. Materials and methods To study if myofibroblasts-as an evidence of tissue microtrauma-are more abundant at EMJZ in AM-uteri, a case-control experimental study w…

Adultadenomyosis pathogenesiPathologymedicine.medical_specialtyUterusConnective tissueEndometriummicrotraumaDesmin03 medical and health sciencesEndometrium0302 clinical medicineendometrial–myometrial junctional zoneMetaplasiaMedicineHumansAdenomyosisMyofibroblastscollagen I030219 obstetrics & reproductive medicineurogenital systembusiness.industryMyometriumConnective Tissue Growth FactorObstetrics and Gynecologymedicine.diseaseActinsCTGFmedicine.anatomical_structure030220 oncology & carcinogenesisCase-Control StudiesMyometriumDesminFemalemedicine.symptombusinessReceptors Transforming Growth Factor betaAdenomyosisBiomarkersReproductive sciences (Thousand Oaks, Calif.)
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Ramadan exposure and birth outcomes: a population-based study from the Netherlands.

2020

AbstractBackground:Ramadan, the Islamic month of daytime fasting, is observed by many pregnant Muslims. Although pregnant women are exempt, many prefer to fast. Previous research has shown long-term adverse effects on various health outcomes among the offspring, but evidence on effects on perinatal outcomes is mixed. This study investigates effects of Ramadan during pregnancy among Muslims in the Netherlands.Methods:Data from the Perinatal Registry of the Netherlands (Perined) on all births between 2000 and 2010 to mothers recorded as Mediterranean (i.e. of Turkish/Moroccan descent, a proxy for Muslim) (n = 139,322) or as ethnically Dutch (n = 1,481,435) were used. Ramadan exposure was defi…

AdultfastingOffspringBirth weightMedicine (miscellaneous)MothersGestational AgeLogistic regressionIslamOddsCohort Studies03 medical and health sciencesYoung Adult0302 clinical medicineSDG 3 - Good Health and Well-beingPregnancy0502 economics and businessMedicineBirth WeightHumans030212 general & internal medicineRegistries050207 economicsPerinatal MortalityNetherlandsRamadanPregnancybusiness.industry05 social sciencesbirth outcomesInfant Newbornbirth weightOdds ratioFastingMaternal Nutritional Physiological Phenomenamedicine.diseaseConfidence intervalApgar Score/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingGestationFemalepregnancybusinessDemographyMaternal AgeJournal of developmental origins of health and disease
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La asistencia a juicios y su simulación como nuevos métodos de aprendizaje del Derecho procesal

2014

El presente artículo tiene como fin analizar dos métodos de enseñanza en los que el alumno participa de forma activa: la asistencia a juicios y la simulación de procesos. Estas actividades producen buenos resultados en el aprendizaje del Derecho Procesal, según se desprende de diferentes encuestas en las que se evalúan algunas experiencias docentes

AdvocatsAprenentatge
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Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

2021

Abstract Background Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field. Results Leveraging DNA methylation and SNP data from more than 40,000 individuals, we identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We find evidence for shared genetic loci ass…

AgingMultifactorial InheritanceBLOODEpigenetic clock05 Environmental SciencesbiomarkkeritGenome-wide association studyQH426-470Epigenesis Genetic/dk/atira/pure/core/keywords/icep0302 clinical medicineBiomarkers of agingGWASBiology (General)AdiposityGenetics11832 Microbiology and virology0303 health sciences318 Medical biotechnologyDNA methylation1184 Genetics developmental biology physiologygenomiikkaDna Methylation ; Epigenetic Clock ; Gwasddc:DNA-metylaatioINSIGHTSC-Reactive ProteinepigenetiikkaDNA methylationMENDELIAN RANDOMIZATION/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEducational StatusICEPGenetic MarkersPROVIDESSUSCEPTIBILITY LOCIBioinformaticsQH301-705.5GenomicsBiology03 medical and health sciencesNHLBI Trans-Omics for Precision Medicine (TOPMed) ConsortiumAGESDG 3 - Good Health and Well-beingPlasminogen Activator Inhibitor 1REGRESSIONGeneticsHumansEpigeneticsGeneMETAANALYSIS030304 developmental biologyGenome HumanResearchGenetics of DNA Methylation Consortium06 Biological SciencesLipid MetabolismHuman geneticsGenetic architectureImmunity InnateikääntyminenGenetic LociCpG Islands08 Information and Computing Sciences3111 BiomedicineENRICHMENTepigenetic clock030217 neurology & neurosurgeryBiomarkersGenome-Wide Association StudyGranulocytes
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Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults

2020

Abstract Background In 2016, an expert working group was convened under the auspices of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and formulated consensus recommendations for the conduct of clinical trials for drugs to prevent or treat sarcopenia. Aims The objective of the current paper is to provide a 2020 update of the previous recommendations in accordance with the evidence that has become available since our original recommendations. Methods This paper is based on literature reviews performed by members of the ESCEO working group and followed up with face to face meetings organized for the whole group to make amendments and discuss…

AgingSarcopeniaGeriatrics & GerontologyStandardizationDiseaseReviewRecommendationsFace-to-face0302 clinical medicineQUALITY-OF-LIFEGAIT SPEEDClinical trial; Drug registration; Guidelines; Recommendations; Sarcopenia; Treatment; Aged; Humans; Muscle Strength; Osteoarthritis; Osteoporosis; Pharmaceutical Preparations; Sarcopenia030212 general & internal medicineMUSCLE MASSDIETARY-PROTEINClinical trialPhysical limitationsPharmaceutical Preparations/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPatient-reported outcomeGRIP STRENGTHLife Sciences & Biomedicinemedicine.medical_specialtyNUTRITIONAL-STATUSBODY-COMPOSITION030209 endocrinology & metabolismGuidelines03 medical and health sciencesClinical trial · Sarcopenia · Guidelines · Recommendations · Drug registration · TreatmentSDG 3 - Good Health and Well-beingOsteoarthritismedicineHumansMuscle StrengthDrug registrationAgedScience & Technologybusiness.industryWORKING GROUPmedicine.diseaseComorbidityClinical trialTreatmentSarcopeniaPATIENT-REPORTED OUTCOMESPhysical therapyOsteoporosisGeriatrics and GerontologyPHYSICAL PERFORMANCEbusinessAging Clinical and Experimental Research
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