Search results for "THC"

showing 10 items of 901 documents

Sex-specific differences drive temporal trends and outcomes of patients hospitalized for heart failure in Germany

2020

Despite remarkable improvements in treatment of cardiovascular disease, heart failure (HF) is still characterized by high mortality rate. Sex-specific differences in HF have been described, but underlying reasons are widely unexplored.The nationwide German inpatient sample (2005-2016) was used for this sex-specific analyses. Temporal trends on hospitalizations, mortality, and treatments were analysed and independent predictors of adverse outcomes identified.The analysis comprises 4,538,977 hospitalizations due to HF (52.0%women) in Germany (2005-2016). Although women were older (median 82(IQR75-87) vs.76(69-82),P  0.001), coronary artery disease (CAD, 50.3% vs. 30.7%,P  0.001) was more prev…

Malemedicine.medical_specialtyTime FactorsDatabases FactualAdverse outcomesMEDLINEDisease030204 cardiovascular system & hematologyRisk Assessment03 medical and health sciencesSex Factors0302 clinical medicineGermanyInternal medicineCase fatality ratePrevalencemedicineHumansHospital Mortality030212 general & internal medicineHealthcare DisparitiesAgedAged 80 and overHeart Failurebusiness.industryIncidenceMortality rateIncidence (epidemiology)Health Status Disparitiesmedicine.diseaseSex specificHospitalizationOutcome and Process Assessment Health CareTreatment OutcomeHeart Disease Risk FactorsHeart failureFemaleCardiology and Cardiovascular MedicinebusinessProgress in Cardiovascular Diseases
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Outcomes of a routine invasive strategy in elderly patients with non-ST-segment elevation myocardial infarction from 2005 to 2014: results from the P…

2019

Background Elderly patients (≥75 years old) with non-ST-segment elevation myocardial infarction (NSTEMI) represent a large subgroup of all cases. They are rarely included in randomized trials because of comorbidities and concerns about complications. Furthermore, invasive treatments are used less frequently in this patient group. The aim of this study was to analyze trends in invasive procedures and outcomes in elderly patients with NSTEMI from 2005 to 2014. Patients and methods We analyzed 68 978 elderly patients with NSTEMI enrolled in the prospective, nationwide Polish Registry of Acute Coronary Syndromes from 2005 to 2014. Results Elderly patients accounted for 34.9% of all patients wit…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatment030204 cardiovascular system & hematologyCoronary AngiographyRisk Assessmentlaw.invention03 medical and health sciences0302 clinical medicinePercutaneous Coronary InterventionSex FactorsRandomized controlled triallawPredictive Value of TestsRisk FactorsInternal medicinemedicineST segmentHumans030212 general & internal medicineMyocardial infarctionHospital MortalityRegistriesHealthcare DisparitiesNon-ST Elevated Myocardial InfarctionAgedbusiness.industryAge FactorsPercutaneous coronary interventionGeneral MedicineMiddle Agedmedicine.diseaseConfidence intervalStandardized mortality ratioTreatment OutcomePredictive value of testsRelative riskFemalePolandCardiology and Cardiovascular MedicinebusinessCoronary artery disease
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Equally Interchangeable? How Sex and Gender Affect Transplantation

2019

Organ transplantation as an option to overcome end-stage diseases is common in countries with advanced healthcare systems and is increasingly provided in emerging and developing countries. A review of the literature points to sex- and gender-based inequity in the field with differences reported at each step of the transplant process, including access to a transplantation waiting list, access to transplantation once waitlisted, as well as outcome after transplantation. In this review, we summarize the data regarding sex- and gender-based disparity in adult and pediatric kidney, liver, lung, heart, and hematopoietic stem cell transplantation and argue that there are not only biological but al…

Malemedicine.medical_specialtyWaiting ListsDeveloping country030230 surgeryRisk AssessmentOrgan transplantationDonor Selection03 medical and health sciencesPostoperative ComplicationsSex Factors0302 clinical medicineRisk FactorsmedicineHumansHealthcare DisparitiesIntensive care medicineSocioeconomic statusSex CharacteristicsTransplantationEquity (economics)Donor selectionbusiness.industryGraft SurvivalGender IdentityHealth Status DisparitiesOrgan TransplantationTissue DonorsTransplantationTreatment Outcomesurgical procedures operativeFemale030211 gastroenterology & hepatologybusinessRisk assessmentSex characteristics
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Assessment of quality of care of patients with ST-segment elevation myocardial infarction

2020

Aims:The 2017 European Society of Cardiology guidelines for the management of ST-elevation myocardial infarction recommended assessing quality of care to establish measurable quality indicators in order to ensure that every ST-elevation myocardial infarction patient receives the best possible care. We investigated the quality indicators of healthcare services in Poland provided to ST-elevation myocardial infarction patients.Methods and results:The Polish Registry of Acute Coronary Syndromes is a nationwide, multicentre, prospective study of acute coronary syndrome patients in Poland. For the purpose of assessing quality indicators, we included 8279 patients from the Polish Registry of Acute…

Malemedicine.medical_specialtymedicine.medical_treatmentacute myocardial infarctionQuality indicatorshealthcare system performance030204 cardiovascular system & hematologyCoronary AngiographyCritical Care and Intensive Care MedicineElectrocardiography03 medical and health sciences0302 clinical medicineReperfusion therapyPatient Self-ReportRisk FactorsOutcome Assessment Health CareHumansMedicineST segmentProspective StudiesRegistries030212 general & internal medicineMyocardial infarctionQuality of careAgedQuality of Health CareEjection fractionbusiness.industryPercutaneous coronary interventionGeneral MedicineMiddle Agedmedicine.diseasemortalityHeart failureEmergency medicineST Elevation Myocardial InfarctionFemaleCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal. Acute Cardiovascular Care
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The prevalence of musculoskeletal disorders and low back pain among Italian nurses. An observationalstudy

2020

Background and aim of the work: Musculoskeletal disorders and low back pain have negative impact amongst Italian nurses who work in hospital. Nursing staff are known to be at risk of developing back disorders, where low back pain has a prevalence from 16% to 60% in the world. This study aims to determine the prevalence of musculoskeletal disorders and low back pain among nurses who working in a Roman hospital. Methods: Cross sectional study was carried out in an Italian hospital and the Nordic Musculoskeletal Questionnaire-IRSST was administered to 256 registered nurses. Logistic regression analyses were performed to understand risk factors associated with pain. Results: Nurses reported dif…

MaleprevalencenurseNursesOriginal Article: Healthcare Professionals: Physical and Psychological ConditionsSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheOccupational DiseasesCross-Sectional StudiesnursingSurveys and QuestionnairesitalyHumansrisk factorsFemaleitaly; low back pain; musculoskeletal disorder; nurse; prevalence; risk factorsmusculoskeletal disorderMusculoskeletal Diseaseslow back pain
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Efficacy of switching between tumor necrosis factor-alfa inhibitors in psoriasis: results from the Italian Psocare registry

2014

Background: Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. Objective: We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discontinuing the first TNF-alfa inhibitor. Methods: Data from all 5423 consecutive patients starting TNF-alfa inhibitor therapy for psoriasis between September 2005 and September 2010 who were included in the Italian Psocare registry were analyzed. Results: In 105 patients who switched to a second TNF-alfa inhibitor who had complete follow-up data, 75% improvement in the Psoriasis …

Maleprimary inefficacy75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitors; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunoglobulin G; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young AdultSWITHCESefficacyTNFpsoriasis; psoriasis arthritis; pharmachological treatmentPASI 75Severity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptCohort StudiesMonoclonalReceptorsSettore MED/35 - Malattie Cutanee E VenereeRegistriesHumanizedtumor necrosis factor-alfa inhibitors.switchingHazard ratioAntibodies MonoclonalMiddle AgedTreatment OutcomeItalyPredictive value of tests75% improvement in the Psoriasis Area Severity Index scoreFemaleDrugPsoriasis Area Severity IndexbiologicTNF-alphaAdultmedicine.medical_specialtytumor necrosis factorDermatology75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitorsAntibodies Monoclonal Humanizedsecondary loss of efficacyRisk AssessmentAntibodiestumor necrosis factor-alfa inhibitorsDrug Administration ScheduleDose-Response RelationshipYoung AdultSettore MED/35Predictive Value of TestsInternal medicinePsoriasisSeverity of illnessmedicineConfidence IntervalsHumansPsoriasisbiologicsAdverse effectPsoriasis; TNF-alphaProportional Hazards ModelsRetrospective Studiespsoriasibiologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor-alfa inhibitors; Adalimumab; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult; 2708Analysis of Variancepharmachological treatmentDose-Response Relationship DrugProportional hazards modelbusiness.industrytumor necrosis factor-alfa inhibitorTumor Necrosis Factor-alphaPASIAdalimumabRetrospective cohort studypsoriasis arthritismedicine.diseaseConfidence intervalInfliximabSurgeryImmunoglobulin GMultivariate AnalysisANTI-TNFAbusiness2708Follow-Up Studies
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Effects of 12-month home-based physiotherapy on duration of living at home and functional capacity among older persons with signs of frailty or with …

2018

Health concerns, such as frailty and osteoporotic fractures decrease functional capacity and increase use of health and social care services in the aging population. The ability to continue living at home is dependent on functional capacity, which can be enhanced by rehabilitation. We study the effects of a 12-month home-based physiotherapy program with 12-month follow-up on duration of living at home, functional capacity, and the use of social and health care services among older persons with signs of frailty, or with a recently operated hip fracture. This is a non-blinded, parallel group, randomized controlled trial performed in South Karelia Social and Health Care District, Finland (popu…

MaleterveyspalvelutTime Factorssosiaalipalvelutmedicine.medical_treatmentvanhuksetyhteisöllinen asuminenlcsh:GeriatricsCommunity-dwellinglaw.inventionStudy Protocolmurtumat0302 clinical medicineRandomized controlled trialQUALITY-OF-LIFElawSurveys and QuestionnairesHealth careMedicine030212 general & internal medicineluunmurtumatFinlandAged 80 and overeducation.field_of_studyHip fractureRehabilitationkotisairaanhoitokotikuntoutusHome Care ServicesFunctional Independence Measurecommunity-dwellingFES-IEXERCISE PROGRAM3. Good healthTreatment OutcomeSocial and health care serviceship fracturesFemaleHEALTHIndependent LivingikääntyneetREHABILITATIONPopulation ageingmedicine.medical_specialtyFrail ElderlykotihoitoPopulation03 medical and health sciencesQuality of life (healthcare)toimintakykyFunctional capacityHumanshome-based physiotherapyeducationMETAANALYSISPhysical Therapy ModalitiesAgedduration of living at homeHip Fracturesbusiness.industryDISABILITYPHYSICAL PERFORMANCE BATTERYADULTSDuration of living at homeHome-based physiotherapymedicine.diseasefrail elderlylonkkaLOWER-EXTREMITY FUNCTIONlcsh:RC952-954.6Nutrition Assessment3121 General medicine internal medicine and other clinical medicineQuality of LifePhysical therapyAccidental FallsGeriatrics and Gerontologybusinesssocial and health care services030217 neurology & neurosurgeryBMC Geriatrics
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Alla ricerca della sicurezza e della qualità: il modello di miglioramento dell'Oncologia Medica nel Policlinico Universitario di Palermo

2015

[In search of safety and quality: the improvement model proposed by the Oncology Department of the Palermo University] Over the past 20 years the field of oncology has product therapeutic innovations that have radically changed the prognosis of the most prevalent malignancies, since introduction of so-called targeted molecular agents. As a result of these changes, also the management of cancer patients has become more complex requiring technologies and skills that involve many professionals (medical oncologists, biologists, molecular geneticists, surgeons, pathologists, radiologists, nurses and psychologists), each engaged in a different stage of the disease, with the common goal of ensurin…

Management of cancer patientmedicine.medical_specialtyChemotherapy; Management of cancer patients; Safety; Dragon Boat; RehabilitationSettore MED/06 - Oncologia Medicabusiness.industryRehabilitationAlternative medicineDiseaseSettore MED/42 - Igiene Generale E ApplicataUniversity hospitalSurgeryNursingRisk Management; Healthcare OrganizationmedicineChemotherapyDragon BoatSafetyQuality of careMedical prescriptionbusinessPratica Medica & Aspetti Legali
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Developing Solutions For Healthcare : Deploying Artificial Intelligence to an Evolving Target

2017

—The pace of deploying artificial intelligence (AI) techniques to healthcare has been speeding up. Many of the initiatives have been technology driven aiming at finding problems matching the new technology while systematic, demand driven search for solutions has been limited. Here we describe the process of identifying opportunities for deploying artificial intelligence to healthcare and social services on regional and national levels in Finland. The process includes idea generation and elaboration using a design thinking method complemented with architectural design for identifying required AI capabilities for the 34 best use cases. In this paper, we focus on the development of use case “M…

Matching (statistics)Process (engineering)Technology pushComputer scienceSocial WelfareDesign thinkingterveysteknologiatekoälytietotekniikkainformation technologydesign thinking0502 economics and businessHealth careUse casehealth informaticsta113business.industry05 social sciences050209 industrial relationshealthcareterveystieto (oppiaineet)Ideationartificial intelligenceterveystieto050211 marketingArtificial intelligencebusinesshealth information systems innovation
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Adolescent boys with asthma – a pilot study on embodied gendered habits

2012

Thomas Westergren,1 Ulla-Britt Lilleaas21Faculty of Health and Sport Science, Department of Health and Nursing Science, University of Agder, Grimstad, Norway; 2Faculty of Humanities and Education, Centre for Gender and Equality, University of Agder, Kristiansand, NorwayPurpose: Asthma is a common chronic disease with gender differences in terms of severity and quality of life. This study aimed to understand the gendered practices of male asthmatic adolescents in terms of living with and managing their chronic disease. The study applied a sociological perspective to identify the gender-related practices of participants and their possible consequences for health and disease.Patients and metho…

Medical educationmedicine.medical_specialtymen’s healthbusiness.industryJournal of Multidisciplinary HealthcareAlternative medicineGeneral MedicineethnomethodologyData scienceFocus groupGrounded theoryqualitative approachDoing genderEthnomethodologyMultidisciplinary approachHealth carefocus groupMedicinebusinessdoing genderGeneral NursingDoveOriginal Researchgrounded theoryJournal of Multidisciplinary Healthcare
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