Search results for "THERP"
showing 10 items of 10 documents
[Herpes Zoster and its prevention in Italy. Scientific consensus statement].
2014
In this paper, an Italian group of experts presents a revision of the available data about epidemiology and prevention of Herpes Zoster (HZ). HZ is an acute viral diseases caused by the reactivation of Varicella Zoster Virus (VZV). HZ is characterized by neurological and dermatological symptoms with a dermatomeric localization. The reactivation of the virus from the latent status in the sensitive ganglia increases with age and failing cell mediated immunity. In Europe, more than 95% of adults presents antibodies against VZV. Incidence of HZ is similar all over the world, related to the age of the population: from 2-3/1000 persons/year in the age group 20 to 50 years to 5/1000 in the 60 year…
Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): reference data for the trunk and application in patients with…
2013
Age- and gender-matched reference values are essential for the clinical use of quantitative sensory testing (QST). To extend the standard test sites for QST-according to the German Research Network on Neuropathic Pain-to the trunk, we collected QST profiles on the back in 162 healthy subjects. Sensory profiles for standard test sites were within normal interlaboratory differences. QST revealed lower sensitivity on the upper back than the hand, and higher sensitivity on the lower back than the foot, but no systematic differences between these trunk sites. Age effects were significant for most parameters. Females exhibited lower pressure pain thresholds (PPT) than males, which was the only si…
Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation A Randomized Clinical Trial
2019
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Postherpetic neuralgia and recalcitrant cystic lesions following herpes zoster: A case report and review of treatment options.
2020
Acute herpes zoster lesions in most cases are self-limited except in older and immunocompromised patients, wherein the pain can cause significant suffering. Postherpetic neuralgia is a painful situation for patients that can compromise the quality of life. Here, we report a 30-year-old healthy young man who developed treatment-resistant postherpetic neuralgia after herpes zoster (fourth/fifth thoracic segment) without any underlying immunocompromised state. He also developed some cystic lesions, which were removed by aspiration and surgery. The skin lesions improved 2 weeks after the surgery and postherpetic neuralgia was completely cured after 5 months, however cystic lesions recurred mult…
Education Students’ Use of Collaborative Writing Tools in Collectively Reflective Essay Papers
2014
Published version of an article in the journal: Journal of Information Technology Education: Research. Also available from the publisher at: http://www.jite.org/documents/Vol13/JITEv13ResearchP091-120Brodahl0463.pdf Open Access Google Docs and EtherPad are Web 2.0 tools providing opportunity for multiple users to work online on the same document consecutively or simultaneously. Over the last few years a number of research papers on the use of these collaborative tools in a teaching and learning environment have been published. This work builds on that of Brodahl, Hadjerrouit, and Hansen (2011) expanding its case study. The theoretical framework is the same as the one underlying Brodahl et a…
Human reliability analysis to support the development of a software project
2017
The Human Reliability Analysis (HRA) is considered as a useful tool in predicting and quantifying the occurrence of human errors during the execution of a specific task. With this recognition, the present paper firstly aims at discussing the support given by HRA methodologies to the fault risk evaluation. Then, the Technique for Human Error Rate Prediction (THERP) is suggested to evaluate the success probability of a software development project.
Association between pain, central sensitization and anxiety in postherpetic neuralgia
2014
Background In postherpetic neuralgia (PHN), dorsal root ganglia neurons are damaged. According to the proposed models, PHN pain might be associated with nociceptive deafferentation, and peripheral (heat hyperalgesia) or central sensitization (allodynia). Methods In 36 PHN patients, afferent nerve fibre function was characterized using quantitative sensory testing and histamine-induced flare analysis. Psychological factors were evaluated with the Hospital Anxiety and Depression Scale (HADS), disease-related quality of life (QoL) with SF-36 and pain with the McGill questionnaire [pain rating index (PRI)]. The patients were also divided into subgroups according to the presence or absence of br…
General therapeutic guidelines
2017
There are currently no methods available that have been proven to promote or accelerate regenerative processes in nerves. This lack often leads to disappointment for both patient and physician.
Reducing the burden of Herpes Zoster in Italy.
2015
Herpes Zoster (HZ) is a viral disease with painful neuro-dermatologic manifestations. Incidence increases with age. In Italy, the estimated incidence is 6.3 cases/1000 person/year; hospital admissions are less than 2%, 69% in patients aged over 65 years. The most frequent complication of HZ is Post-Herpetic Neuralgia (PHN) characterized by metameric pain, allodynia, and hyperalgesia. In Italy 20.6% and 9.2% of HZ patients experience PHN after 3 and 6 months, respectively. Available antiviral and analgesic treatments are relatively unsatisfactory in reducing pain and length of the disease. Prevention has recently become possible with the live attenuated vaccine Oka/Merck. Clinical studies sh…
THERP and HEART integrated methodology for human error assessment
2014
Medical errors are one of the leading causes of death and injury in radiation therapy administration as reported in the literature. This point out an overall deficiency in management allowing patient treatment in the absence of suitable quality assurance processes. Clinical records of major accidental exposure events in radiotherapy show that there is a combination of factors contributing to the accident such as deficient staff training, lack of independent checks, lack of quality control procedures, and absence of overall supervision. Another finding is that training generally addresses only normal situations and does not prepare radiotherapy staff for unusual situations, resulting in a la…