Search results for "THICKNESS"

showing 10 items of 307 documents

Advancement Perforator Cheek Flap for Aesthetic One-Stage Reconstruction of Postoncological Extended Split-Thickness Defects of the Nasal Sidewall

2013

Aesthetic reconstruction of soft tissue nasal sidewall loss has an important influence on the appearance of the nose. The unique character of this subunit and the complex relationships with a number of different facial or nasal subunits make the excision of large tumors difficult to manage. Numerous techniques are described in the literature, but a primary reconstruction with a final good result is not often possible. The authors develop an advancement cheek flap for an aesthetic one-stage reconstruction of postoncological extended nasal sidewall defects. Between January 2009 and July 2012, 16 patients (mean age, 63.3 yr) underwent excision of skin tumors of nasal sidewall and immediate rec…

Malemedicine.medical_specialtyArticle Subjectmedicine.medical_treatmentNose NeoplasmsSettore MED/19 - Chirurgia Plasticalcsh:Medicinelcsh:TechnologyNose neoplasmSurgical FlapsGeneral Biochemistry Genetics and Molecular BiologyCheek flapRhinoplastymedicine.arterymedicineHumansSurgical Flapslcsh:ScienceNoseAgedGeneral Environmental Sciencelcsh:Tbusiness.industryCarcinomalcsh:RNose Deformities AcquiredSoft tissueSkin TransplantationGeneral MedicineAnatomyMiddle AgedCheekRhinoplastySuperficial temporal arterySurgeryCheekmedicine.anatomical_structureClinical StudyFemalelcsh:QAdvancement Perforator Cheek Flap Extended Split-Thickness Defects Nasal Sidewall reconstructionbusiness
researchProduct

The association between coronary microvascular dysfunction and carotid intima media thickness in patients with cardiac syndrome X

2016

Abstract Objective The aim of this study was to evaluate in patients with cardiac syndrome X (CSX), using validated angiography indices, coronary blood flow and myocardial perfusion of the microcirculation to assess whether there is greater microvascular dysfunction in patients with increase of carotid intima media thickness (C-IMT), compared to those who do not have. Methods Our study was performed on a population 124 patients with CSX that underwent coronary angiography and carotid ultrasound. We divided the sample into two categories: patients with increase of C-IMT and those without increase. We calculated Gibson and Yusuf indices for each patient based on angiographic images, including…

Malemedicine.medical_specialtyCoronary angiographyPopulation030204 cardiovascular system & hematologyCarotid Intima-Media ThicknessUltrasound carotidMicrocirculationC-reactive protein03 medical and health sciences0302 clinical medicineCardiac syndrome XInternal medicinemedicineHumanscardiovascular diseases030212 general & internal medicineeducationAgedMicrovascular Anginaeducation.field_of_studyCarotid intima media thickneCardiac syndrome Xmedicine.diagnostic_testbusiness.industryMicrocirculationBlood flowMiddle Agedmedicine.diseaseCoronary VesselsCoronary arteriesCarotid Arteriesmedicine.anatomical_structureIntima-media thicknessAngiographycardiovascular systemCardiologyFemalebusinessCardiology and Cardiovascular MedicineTIMI
researchProduct

Carotid intima media thickness and coronary atherosclerosis linkage in symptomatic intermediate risk patients evaluated by coronary computed tomograp…

2014

Background: There is a growing evidence that carotid intima media thickness (CIMT) is associated with coronary artery disease (CAD) and it should be used as a predictor of atherosclerotic burden of coronary arteries. However, these studies have been performed by using invasive coronary angiography (ICA) and in high-risk patients for CAD. The purpose of this study was to evaluate the correlation between CIMT by ultrasound and coronary atherosclerosis in symptomatic intermediate risk patients by coronary computed tomography angiography (CCTA). Methods: We enrolled 204 consecutive symptomatic patients (mean age: 61 +/- 10; men: 118) and intermediate risk for CAD. All patients underwent CIMT ul…

Malemedicine.medical_specialtyCoronary atherosclerosiCoronary Artery DiseaseCoronary AngiographyCarotid Intima-Media ThicknessSeverity of Illness IndexCoronary artery diseasePredictive Value of TestsRisk FactorsInternal medicinemedicineCoronary computed tomography angiographyHumanscardiovascular diseasesCoronary atherosclerosisAgedCarotid intima media thicknebusiness.industryUltrasoundCoronary computed tomography angiographyMiddle Agedmedicine.diseaseCoronary arteriesmedicine.anatomical_structureIntima-media thicknessROC Curvecardiovascular systemCardiologyFemaleRadiologyCardiology and Cardiovascular MedicinebusinessIntermediate riskTomography X-Ray ComputedArteryInternational journal of cardiology
researchProduct

Exenatide once-weekly improves metabolic parameters, endothelial dysfunction and carotid intima-media thickness in patients with type-2 diabetes: An …

2019

AIM: To evaluate the effect of exenatide long acting release (LAR) on carotid intima-media thickness (IMT) and endothelial function in patients with type 2 diabetes mellitus. METHODS: Sixty subjects with type 2 diabetes mellitus were treated with exenatide LAR as add-on to stable doses of metformin for 8 months in an open label study. Anthropometric variables, lipid profile and glycemic parameters were assessed by routine analysis. Carotid IMT by Doppler ultrasound and endothelial function by flow-mediated dilation of the brachial artery were also assessed. RESULTS: Exenatide significantly improved fasting glycaemia (from 8.8 ± 2.8 to 7.3 ± 2.2 mmol/L, p < 0.0001), HbA1c (from 8.0 ± 0.4 …

Malemedicine.medical_specialtyEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismType 2 diabetesCarotid Intima-Media ThicknessCarotid intima-media thickne03 medical and health sciences0302 clinical medicineEndocrinologyRisk FactorsInternal medicineDiabetes mellitusInternal MedicineMedicineHumansHypoglycemic Agentscardiovascular diseases030212 general & internal medicineProspective StudiesEndothelial dysfunctionmedicine.diagnostic_testbusiness.industryType 2 Diabetes MellitusGeneral MedicineMiddle Agedmedicine.diseaseCardiovascular diseaseAtherosclerosisMetforminIntima-media thicknessDiabetes Mellitus Type 2Atherosclerosicardiovascular systemCardiologyExenatideFemalebusinessLipid profileExenatidemedicine.drugDiabetes research and clinical practice
researchProduct

Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study.

2014

Background Liraglutide, a long-acting glucagon-like peptide-1 (GLP-1) analog, has several non- glycemic properties, but its effect on carotid intima-media thickness (IMT), a recognized marker of subclinical atherosclerosis, is still unknown. Methods A prospective study of 8 months duration in 64 patients with type-2 diabetes and no prior history of coronary artery disease evaluated whether adding liraglutide to metformin affects carotid IMT, measured by color doppler ultrasound. Results After 8 months, fasting glucose decreased by 2.1 mmol/l and HbA1c by 1.9% (p < 0.01 for all). Liraglutide reduced total-cholesterol and triglycerides by 10%, and LDL-cholesterol by 19%, whereas HDL-cholester…

Malemedicine.medical_specialtyEndocrinology Diabetes and MetabolismPilot ProjectsType2 diabetesType 2 diabetesCarotid Intima-Media ThicknessCoronary artery diseaseGlucagon-Like Peptide 1Internal medicineDiabetes mellitusLiraglutide Carotid intima-media thickness Cardiovascular risk Type2 diabetesmedicineHumansHypoglycemic AgentsProspective Studiescardiovascular diseasesProspective cohort studyGlycemicAgedOriginal Investigationbusiness.industryLiraglutideLiraglutideMiddle Agedmedicine.diseaseCardiovascular risk3. Good healthMetforminEndocrinologyIntima-media thicknessDiabetes Mellitus Type 2Cardiologycardiovascular systemFemalebusinessCardiology and Cardiovascular Medicinemedicine.drug
researchProduct

Frailty and Risk of Cardiovascular Diseases in Older Persons: The Age, Gene/Environment Susceptibility-Reykjavik Study

2017

Frailty is a risk factor for cardiovascular diseases (CVD), but the studies available have not considered the presence of subclinical atherosclerotic disease as potential confounders. We investigated the association between frailty and the onset of CVD independently of subclinical atherosclerotic disease. For this reason, a sample of 3818 older participants participating in the Age, Gene/Environment Susceptibility-Reykjavik Study without CVD at baseline was followed for a median of 8.7 years. Frailty was defined as the presence of ≥3 among five Fried's criteria (unintentional weight loss, low physical activity level, weakness, exhaustion, and slow gait speed). Incident CVD was defined as on…

Malemedicine.medical_specialtyFrail Elderlyaging; cardiovascular disease; frailty; risk factorfrailty030204 cardiovascular system & hematologyCoronary artery disease03 medical and health sciences0302 clinical medicineWeight lossRisk Factorscardiovascular diseaseInternal medicinemedicineHumanscardiovascular disease risk factor aging frailtyGenetic Predisposition to Disease030212 general & internal medicinecardiovascular diseasesRisk factorStrokeSubclinical infectionAgedbusiness.industryIncidence (epidemiology)IncidenceagingOriginal Articlesmedicine.disease3. Good healthIntima-media thicknessrisk factorCardiovascular DiseasesHeart failurePhysical therapyFemaleGene-Environment InteractionGeriatrics and Gerontologymedicine.symptombusinessFollow-Up Studies
researchProduct

The changes in resting anal pressure after performing full-thickness rectal advancement flaps.

2017

Background: Advancement flap is an accepted approach for treating complex fistula-in-ano. The purpose was to evaluate the changes in resting pressure along the anal canal after performing a full-thickness flap. Methods: Manometric review of patients who have undergone a full-thickness rectal advancement flap procedure for complex anal fistulas of cryptoglandular origin. Recurrence and continence were evaluated. Resting Anal Pressure was assessed along the anal canal by two measures: maximum resting pressure(MRP) and inferior resting pressure(IRP) at 0.5 cm from the anal verge. Results: 119 patients were evaluated. Overall recurrence rate was5.9%. Anal continence was maintained intact in 76.…

Malemedicine.medical_specialtyManometryAnal Canal030230 surgerySurgical FlapsComplex anal fistulaAnal continence03 medical and health sciences0302 clinical medicinePressureMedicineHumansRectal FistulaRectal advancement flapProspective StudiesDigestive System Surgical Proceduresbusiness.industryUrethral sphincterAnal MarginGeneral MedicineAnal manometryAnal canalMiddle AgedSurgerymedicine.anatomical_structure030220 oncology & carcinogenesisAnal vergeAnal manometrySurgeryFull thicknessFemalebusinessAmerican journal of surgery
researchProduct

Factors predicting normal visual acuity following anatomically successful macular hole surgery

2021

Purpose: To assess the incidence of normal vision following anatomically successful macular hole surgery and associated clinical variables. Methods: Multicentre, retrospective chart review. Preoperative, intraoperative and postoperative clinical data were extracted from electronic medical records from seven European vitreoretinal units. Inclusion criteria were as follows: eyes undergoing primary vitrectomy for idiopathic full-thickness macular hole from January 2015 to January 2018; postoperative macular hole closure confirmed by spectral domain optical coherence tomography (OCT); preoperative pseudophakia or phakic eyes receiving combined cataract surgery; one-year follow-up. The primary o…

Malemedicine.medical_specialtyMultivariate analysisVisual acuitygenetic structuresPseudophakiamacular hole closuremedicine.medical_treatmentVisual AcuityvitrectomyVitrectomyTime-to-Treatment03 medical and health sciences0302 clinical medicinefull-thickness macular hole; idiopathic macular hole; macular hole closure; macular hole surgery; vitrectomymedicineFull-thickness macular holeHumansMacular holeAgedRetrospective Studiesfull-thickness macular holeidiopathic macular holebusiness.industryGeneral MedicineOdds ratioCataract surgeryMiddle Agedmedicine.diseaseRetinal Perforationseye diseasesConfidence intervalSurgeryOphthalmologyTreatment Outcomemacular hole surgery030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryTomography Optical CoherenceFollow-Up Studies
researchProduct

Evolution of 5 cardiovascular magnetic resonance–derived viability indexes after reperfused myocardial infarction

2007

The objective of this study was to evaluate the simultaneous evolution of 5 cardiovascular magnetic resonance-derived myocardial viability indexes.We studied 72 patients with a first ST-elevation myocardial infarction and sustained TIMI 3 flow. In the first week and in the sixth month of the study, using cardiovascular magnetic resonance imaging, we determined wall thickening (WT) and the following viability indexes: wall thickness, WT with low-dose dobutamine, microvascular perfusion in first-pass imaging, microvascular obstruction in late-enhancement imaging, and transmural extent of necrosis.In 250 dysfunctional segments, the evolution outcomes for the viability indexes were as follows: …

Malemedicine.medical_specialtyNecrosisReperfused myocardial infarctionMyocardial InfarctionMyocardial ReperfusionInternal medicinemedicineHumansMyocardial infarctionmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance ImagingCirculatory systemCardiologyFemaleDobutaminemedicine.symptomCardiology and Cardiovascular MedicineWall thicknessNuclear medicinebusinessTIMImedicine.drugAmerican Heart Journal
researchProduct

Focal cortical damage parallels cognitive impairment in minimal hepatic encephalopathy

2012

Little attention has been paid to cortical integrity in patients with minimal hepatic encephalopathy (MHE), although cognitive functions affected in early stages of liver disease are mainly allocated in different neocortical structures. Here we used cortical surface-based analysis techniques to investigate if patterns of cortical thinning accompany the mildest form of HE. To aim this goal, cortical thickness obtained from high-resolution 31 magnetic resonance imaging (MRI) was measured in patients with no MHE (NMHE), MHE, and healthy controls. Further correlation analyses were performed to examine whether scores in the critical flicker frequency (CFF) test, and blood ammonia levels accounte…

Malemedicine.medical_specialtyPathologyCognitive NeuroscienceMinimal hepatic encephalopathyPrecuneusFlicker fusion thresholdNeuropsychological TestsCortical thicknessLiver diseaseInternal medicineImage Interpretation Computer-AssistedmedicineHumansHepatic encephalopathyTemporal cortexCerebral Cortexmedicine.diagnostic_testMagnetic resonance imagingCognitionMiddle Agedmedicine.diseaseEarly diagnosisMagnetic Resonance ImagingCalcarine sulcusmedicine.anatomical_structureEarly DiagnosisCognitive impairmentNeurologyHepatic cirrhosisHepatic EncephalopathyCardiologyFemalePsychologyCognition Disordershuman activities
researchProduct