Search results for "THS"

showing 10 items of 696 documents

Medium-term Culture of Normal Human Oral Mucosa: A Novel Three-dimensional Model to Study the Effectiveness of Drugs Administration

2012

Tissue-engineered oral mucosal equivalents have been developed for in vitro studies for a few years now. However, the usefulness of currently available models is still limited by many factors, mainly the lack of a physiological extracellular matrix (ECM) and the use of cell populations that do not reflect the properly differentiated cytotypes of the mucosa of the oral cavity. For this reason, we have developed a novel three-dimensional culture model reflecting the normal architecture of the human oral mucosa, with the main aim of creating a better in vitro model where to test cellular responses to drugs administration. This novel 3D cell culture model (3D outgrowth) was set up using an arti…

KeratinocytesPathologymedicine.medical_specialtyCell Culture TechniquesModels BiologicalExtracellular matrix3D cell cultureMatrigelMicroscopy Electron TransmissionSettore MED/28 - Malattie OdontostomatologicheIn vivoLamininDrug DiscoverymedicineHumansOral mucosaPharmacologyLamina propriaMicroscopy Confocal3d Outgrowths; Human Oral Mucosa; Matrigel; Drugs administrationTissue EngineeringbiologySettore BIO/16 - Anatomia UmanaMouth MucosaFibroblastsIn vitroHuman Oral MucosaExtracellular MatrixCell biologyFibronectinDrug Combinationsmedicine.anatomical_structureSettore CHIM/09 - Farmaceutico Tecnologico Applicativobiology.proteinProteoglycansCollagenLaminin3d OutgrowthDrugs administrationCurrent Pharmaceutical Design
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Evaluación de procesos de planificación y gestión territorial : un aporte metodológico desde una revisión de enfoques.

2020

La ‘Nueva Planificación Territorial Estratégica’ reaparecida en Europa a finales del siglo XX incorpora de manera intrínseca la necesidad de evaluación de los Planes de Ordenación Territorial. Esta evaluación no puede centrarse únicamente en evaluar el impacto de los planes, sino que debe realizarse también poniendo el foco en los procesos técnicos en los que se producen bienes materiales y la generación de conocimiento. El presente trabajo pretende aportar el marco metodológico para poder desarrollar un instrumento de evaluación de procesos de planificación y gestión de planes de ordenamiento territorial.
  Mediante el uso de una matriz de análisis, se comparan distintos enfoques de e…

Knowledge generationProcess management:GEOGRAFÍA [UNESCO]Land useWork (electrical)Computer scienceGeneral MedicineProcess evaluationStrengths and weaknessesUNESCO::GEOGRAFÍA
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Introduction to Korean Spirituality

2019

This work was supported by the Seed Program for Korean Studies under the auspices of the Republic of Korea Ministry of Education and the Korean Studies Promotion Service of the Academy of Korean Studies.

Korejiešu vietējie dieviService (business)Korejiešu šamanismsbusiness.industryKorean studiesmedia_common.quotation_subject:HUMANITIES and RELIGION [Research Subject Categories]Korejiešu reliģijaKorean Local GodsPublic relationsKorean MythsKorejas modernā literatūraThe RepublicModern Literature in KoreaPromotion (rank)Work (electrical)Korean ReligionsPolitical scienceSpiritualityChristian ministryKorean Shamanismbusinessmedia_common
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Early and midterm outcomes of bioresorbable vascular scaffolds for ostial coronary lesions: insights from the GHOST-EU registry.

2016

Aims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset, with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term, but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA), left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death, target vessel m…

LCX (29Target lesionMale52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostialp= 0.035)medicine.medical_treatmentMyocardial Infarction304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14Coronary Artery Disease030204 cardiovascular system & hematologyCoronary artery diseasebut their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA)0302 clinical medicineAbsorbable Implants030212 general & internal medicineMyocardial infarctionCircumflexRegistriesTissue Scaffolds32%)Drug-Eluting StentsMiddle AgedThrombosisCoronary VesselsAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA) left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death target vessel myocardial infarction or target lesion revascularisation. The database included a total of 1549 lesions in 1304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14; 16%) LCX (29; 32%) or LAD (47; 52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostial p= 0.618) post-dilation in 43% (versus 58% in the non-ostial group p= 0.008). At quantitative coronary angiography treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37] p= 0.035) but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groups respectively log-rank p= 0.005). The device-oriented composite endpoint occurred respectively in 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025 HR 2.65 [1.41-4.97]).OstiumAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subsetTreatment Outcomein 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025CardiologyFemale549 lesions in 1medicine.symptomCardiology and Cardiovascular MedicineAdultpost-dilation in 43% (versus 58% in the non-ostial groupmedicine.medical_specialtyor LAD (47HR 2.65 [1.41-4.97])but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groupsrespectivelyLesion03 medical and health sciencesPercutaneous Coronary Interventionwith higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long termleft anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular deathInternal medicinemedicineHumanstarget vessel myocardial infarction or target lesion revascularisation. The database included a total of 1Agedp= 0.008). At quantitative coronary angiographybusiness.industryPercutaneous coronary interventionp= 0.618)treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37]log-rank p= 0.005). The device-oriented composite endpoint occurredmedicine.diseaseSurgery16%)businessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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THE FATE OF ZR AND HF IN AQUATIC SYSTEMS UNDER THE EFFECTS OF SOLID-LIQUID INTERFACE PROCESSES, INTERPRETED IN THE LIGHT OF BEHAVIOUR OF RARE EARTHS …

2012

LIGHT OF BEHAVIOUR OF RARE EARTHS ELEMENTS AND YTTRIUM.THE EFFECTS OF SOLID-LIQUID INTERFACE PROCESSESTHE FATE OF ZR AND HF IN AQUATIC SYSTEMSSettore GEO/08 - Geochimica E Vulcanologia
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Rational Design of Lanthanoid Single-Ion Magnets: Predictive Power of the Theoretical Models

2016

We report two new single‐ion magnets (SIMs) of a family of oxydiacetate lanthanide complexes with D3 symmetry to test the predictive capabilities of complete active space ab initio methods (CASSCF and CASPT2) and the semiempirical radial effective charge (REC) model. Comparison of the theoretical predictions of the energy levels, wave functions and magnetic properties with detailed spectroscopic and magnetic characterisation is used to critically discuss the limitations of these theoretical approaches. The need for spectroscopic information for a reliable description of the properties of lanthanide SIMs is emphasised. SPINMOL ERC-CoG-647301 DECRESIM MAT2014-56143-R CTQ2014-52758-P CTQ2011-2…

LanthanideElectronic structureUNESCO::QUÍMICAAb initioEstructura electrònicaElectronic structure010402 general chemistry01 natural sciences:QUÍMICA [UNESCO]CatalysisEffective nuclear chargeComputational chemistryRare earthsComplete active spaceWave function010405 organic chemistryChemistryOrganic ChemistryGeneral ChemistrySymmetry (physics)Terres rares0104 chemical sciencesImantsMagnetMagnetsAtomic physics
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Rare earths, zirconium and hafnium distribution in coastal areas: The example of Sabella spallanzanii (Gmelin, 1791)

2016

The Zr, Hf, Y and lanthanide (REE) distribution in biological tissues of Sabella spallanzanii and Styela plicata species collected from two harbours from the northern Sicily is studied for providing information regarding the Zr, Hf and REE uptake from the environment. Previous studies determined the fractionation of dissolved REE scavenged on binding sites onto biological surfaces. By comparing the recognised shale-normalised REE patterns of studied samples with evidence from reference data, the observed behaviour of these elements in biological tissues of Sabella spallanzanii and Styela plicata is interpreted to result from the preferential uptake of intermediate REE onto carboxylic sites.…

LanthanideSabella spallanzaniiEnvironmental EngineeringHealth Toxicology and Mutagenesischemistry.chemical_elementMineralogyFractionation010501 environmental sciences010502 geochemistry & geophysics01 natural sciencesRare earths Sabella spallanzanii Styela plicataAnimalsEnvironmental ChemistryTissue DistributionSicilyDissolutionVehicle Emissions0105 earth and related environmental sciencesZirconiumbiologyPublic Health Environmental and Occupational HealthDustPolychaetaGeneral MedicineGeneral Chemistrybiology.organism_classificationPollutionHafniumStyela plicatachemistryEnvironmental chemistryBioaccumulationMetals Rare EarthZirconiumHafniumEnvironmental Monitoring
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Interspecific associations among larval helminths in fish

2001

Various processes can generate associations between the larvae of different helminth species in their fish intermediate or paratenic host. We investigated the pairwise associations among larval helminth species in eight different fish populations, using two different coefficients of associations, in order to determine in what situations they are strongest. All helminth species included use the fish studied as either their second intermediate host or their paratenic host, and are acquired by the fish when it ingests an infected first intermediate host. The intensity of infection correlated positively with fish length for most helminth species. Pairs of species which both exhibited positive c…

LarvaEcologyEcologyHost (biology)FishesIntermediate hostZoologyInterspecific competitionBiologyStatistics NonparametricHost-Parasite InteractionsFish DiseasesInfectious DiseasesHelminthsParatenicparasitic diseasesAnimalsParasite hostingFish <Actinopterygii>HelminthsParasitologyHelminthiasis AnimalFinlandInternational Journal for Parasitology
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Parasite assemblages in the Western whip snakeHierophis viridiflavus carbonarius(Colubridae) from southern Italy

2012

AbstractParasite assemblages of the Western whip snakeHierophis viridiflavus carbonariuswere investigated from the Calabria region in southern Italy. A total of 14 parasite taxa including 6 nematodes, 3 acanthocephalans, 2 cestodes, 2 digeneans and a single pentastomid was identified. Within the study area,H. v. carbonariusserves as the final host for seven species of helminths, of which only four (Hexametra quadricornis,Kalicephalus viperae,Paracapillaria sonsinoiandRenifer aniarum) can be considered as snake specialists, while one (Oswaldocruzia filiformis) is shared with other reptiles and amphibians, and two (Paradistomum mutabileandRhabdias fuscovenosa) with lizards. A large proportion…

LarvabiologyEcologyHost (biology)Parasitic Diseases AnimalFaunaColubridaeVertebrateBiodiversityGeneral Medicinebiology.organism_classificationItalyParatenicbiology.animalColubridaeAnimalsHelminthsParasite hostingParasitesAnimal Science and ZoologyParasitologyJournal of Helminthology
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CO(2)-laser treatment of laryngeal amyloidosis.

2003

Four consecutive female patients (age: 14–47 years) with laryngeal amyloidosis, treated with endoscopic CO2-laser surgery, entered the study. All patients underwent periodic microlaryngoscopies following surgery to confirm the adequacy of the surgical resection. Recurrences or suspected lesions were resected and fibrin deposits were removed to prevent the formation of synechiae or healing adhesions. After two negative microlaryngoscopies, performed two months apart, the patients were followed-up approximately every six months over a period from six months to 18 years, with no evidence of recurrences. The endoscopic CO2-laser technique is highly effective in the treatment of localized laryng…

Laser surgeryLarynxSurgical resectionAdultmedicine.medical_specialtyEvery Six MonthsAdolescentmedicine.medical_treatmentFibrinLaryngeal DiseasesCo 2 laserLaryngeal amyloidosisFemale patientmedicineHumansbiologyLaryngoscopybusiness.industryGeneral MedicineAmyloidosisCarbon DioxideMiddle AgedSurgerymedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologybiology.proteinFemaleLaser TherapyLarynxbusinessThe Journal of laryngology and otology
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