Search results for "TIME"

showing 10 items of 12336 documents

Three-Year Results of Hydrus Microstent with Phacoemulsification

2019

Abstract We report the 3-year IOP efficacy of the implantation of the Schlemm’s canal Hydrus® Microstent (Ivantis®) combined with phacoemulsification versus phacoemulsification alone

medicine.medical_specialtyTime Factorsgenetic structuresmedicine.medical_treatmentGlaucoma01 natural sciencesCataract03 medical and health sciences0302 clinical medicineOphthalmologymedicineHumansSingle-Blind MethodProspective Studies0101 mathematicsGlaucoma Drainage ImplantsMiniaturizationPhacoemulsificationbusiness.industry010102 general mathematicsGlaucomaGeneral MedicinePhacoemulsificationmedicine.diseaseeye diseasesTreatment Outcome030221 ophthalmology & optometryStentssense organsbusinessFollow-Up Studies
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A decade of trials of interferon-alpha for chronic hepatitis C. A meta-regression analysis

2003

The most relevant randomized controlled trials of interferon-alpha (IFN) for naive patients with chronic hepatitis C (CHC) published in a decade, just before appearance of pegylated IFN trials in 2000, were included in this paper. Its purpose is to review the relationship between sustained biochemical response in active versus control group versus usual clinical variables as IFN regimens, cirrhosis, genotype and versus less frequently addressed variables as funding, methodological quality or location of principal author. Meta-analysis estimates of global treatment effect varied according to trial design: group 1=IFN versus placebo/no treatment, 32 RCTs, 2499 pts, OR 9.5 (6.3-14.2); group 2a…

medicine.medical_specialtyTime FactorsinteractionAlpha interferonSubgroup analysisLogistic regressionPlaceborandom effects modellaw.inventionchemistry.chemical_compoundRandomized controlled triallawInternal medicinemeta-regressionmedicineHumansPharmacology (medical)Meta-regressionInterferon alfaRandomized Controlled Trials as Topicbusiness.industrylogistic regressionRibavirinInterferon-alphaGeneral MedicineHepatitis C ChronicLogistic ModelsTreatment OutcomechemistryImmunologyfixed effects modelbusinessmedicine.drugContemporary Clinical Trials
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Effect of Atrial Capture Beats on the Subsequent Cycle During Slow Common Atrioventricular Nodal Reentry Tachycardia

2013

medicine.medical_specialtyTime Factorsmedicine.diagnostic_testbusiness.industryCardiac anatomyAtrial arrhythmiasMiddle AgedNodal diseasePredictive Value of TestsPhysiology (medical)Predictive value of testsInternal medicineAtrial captureElectrocardiography AmbulatoryTachycardia SupraventricularmedicineCardiologyHumansTachycardia Atrioventricular Nodal ReentryTachycardia ParoxysmalCardiology and Cardiovascular MedicinebusinessElectrocardiographyJournal of Cardiovascular Electrophysiology
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The effects of transdermal testosterone and oestrogen therapy on dry eye in postmenopausal women: a randomised, placebo-controlled, pilot study

2016

Aims Sex hormones could provide a future treatment avenue for dry eye post menopause. However, there are few well-controlled studies. This study investigates the impact of testosterone and oestrogen on dry eye symptoms and signs in postmenopausal women. Methods A randomised double-blind placebo-controlled pilot study was conducted involving 40 women with dry eye (age 63.9±5.1 years, 13.2±6.3 years post menopause). Ten women were assigned to each of four treatment groups: transdermal testosterone, oestradiol, testosterone/oestradiol combination and placebo. Assessment at baseline and after 8 weeks: ocular symptoms, tear osmolarity, tear stability, tear secretion, meibomian gland assessment, …

medicine.medical_specialtyTime Factorsmedicine.drug_classMeibomian glandPhysiologyPilot ProjectsAdministration CutaneousPlacebo03 medical and health sciencesCellular and Molecular Neurosciencechemistry.chemical_compound0302 clinical medicineDehydroepiandrosterone sulfateDouble-Blind MethodInternal medicineHumansMedicineTestosteroneTear secretionRetrospective Studies030219 obstetrics & reproductive medicinebusiness.industryMeibomian GlandsEstrogensTestosterone (patch)Middle AgedAndrogeneye diseasesSensory SystemsPostmenopauseOphthalmologyTreatment Outcomemedicine.anatomical_structureEndocrinologychemistryTearsAndrogens030221 ophthalmology & optometryTearsDry Eye SyndromesFemalesense organsbusinessFollow-Up StudiesHormoneBritish Journal of Ophthalmology
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The use of a new kind of low profile retractor for arteriovenous fistula procedure simplifies and speeds up the intervention

2009

Purpose The aim of this study was to demonstrate the effectiveness of a new kind of disposable surgical retractor in arteriovenous fistula (AVF) procedures in order to achieve an easier, faster and safer surgical intervention. Methods Between January and June 2008, 22 AVF procedures were performed using the 3PAWS ReeTrakttrade; (Insightra Inc. - Irvine, Ca., USA) a self-retaining, low profile retractor. An equivalent patient sample, in which an AVF was performed using conventional retraction devices, was considered for comparison of the intra- and post-operative results. Results In all of the 22 AVF procedures performed, the ReeTrakt™ system has simplified the performance of the surgical te…

medicine.medical_specialtyTime Factorsmedicine.medical_treatment030232 urology & nephrologyArteriovenous fistulaarterioveunous fistula retractors030204 cardiovascular system & hematology03 medical and health sciencesArteriovenous Shunt Surgical0302 clinical medicineOperating timeHumansMedicinePatient groupDisposable EquipmentReduction (orthopedic surgery)Brachiocephalic VeinsRetrospective StudiesSurgical teamSurgical instrumentationSurgical Fixation Devicebusiness.industryEquipment DesignSurgical Instrumentsmedicine.diseasearteriovenous fistulaReeTrakt systemSurgeryRetractorForearmSettore MED/18 - Chirurgia GeneraleTreatment OutcomeNephrologyRadial ArterySurgerybusiness
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Chick embryo retina development in vitro: the effect of insulin.

1995

In this paper we study the development of chick embryo retina cultured in vitro and the effects exerted by insulin. Retinas were removed from 7-day embryos and cultured in serum- and hormone-free medium for 7 additional days. Under these conditions retinal cells survived and underwent cholinergic differentiation, as previously ascertained by Hausman et al. (Dev. Brain Res., 1991, 59: 31-37). However, a great retardation of development was noted compared to uncultured control, 14-day retina. In fact both wet weight and DNA and protein content increased much slower than in ovo and the tubulin content decreased below even the starting value. In addition, although after 7 days in culture retina…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentBlotting WesternChick EmbryoIn ovoBiochemistryCulture Media Serum-FreeRetinaCholine O-AcetyltransferaseCellular and Molecular Neurosciencechemistry.chemical_compoundParacrine signallingOrgan Culture TechniquesLeucineTubulinInternal medicinemedicineAnimalsInsulinAspartate AminotransferasesAutocrine signallingRetinabiologyDose-Response Relationship DrugInsulinEmbryoRetinalCell DifferentiationGeneral MedicineDNAInsulin receptorKineticsEndocrinologymedicine.anatomical_structurechemistryPhosphopyruvate HydrataseProtein Biosynthesisbiology.proteinThymidineNeurochemical research
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Comparison of Percutaneous Coronary Intervention (With Drug-Eluting Stents) Versus Coronary Artery Bypass Grafting in Women With Severe Narrowing of …

2014

Women typically present with coronary artery disease later than men with more unfavorable clinical and anatomic characteristics. It is unknown whether differences exist in women undergoing treatment for unprotected left main coronary artery (ULMCA) disease. Our aim was to evaluate long-term clinical outcomes in women treated with percutaneous coronary intervention (PCI) with drug-eluting stents versus coronary artery bypass grafting (CABG). All consecutive women from the Drug-Eluting stent for LefT main coronary Artery disease registry with ULMCA disease were analyzed. A propensity matching was performed to adjust for baseline differences. In total, 817 women were included: 489 (59.8%) unde…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentCoronary AngiographySeverity of Illness IndexCoronary artery diseasePercutaneous Coronary InterventionRisk FactorsInternal medicinemedicineHumansMyocardial infarctionRegistriesCoronary Artery BypassPropensity ScoreAgedRetrospective Studiesbusiness.industryCoronary StenosisPercutaneous coronary interventionStentDrug-Eluting StentsOdds ratiomedicine.diseaseCoronary VesselsSurgerymedicine.anatomical_structureTreatment OutcomeDrug-eluting stentConventional PCICardiologyFemaleCardiology and Cardiovascular MedicinebusinessArteryFollow-Up Studies
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Coronary stent implantation in acute vessel closure 48 hours after an unsatisfactory coronary angioplasty

1990

We report the implantation of a balloon-expandable stent in a patient with acute vessel closure in the state of evolving myocardial infarction following 48 hr after unsatisfactory coronary angioplasty. The stent was implanted after successful recanalization of an occluded left anterior descending artery, with repeated unsatisfactory results of balloon angioplasty. Adjunct thrombolytic therapy was contraindicated. No residual stenosis was documented in immediate control angiograms, or after 24 hr, 3 weeks, and 4 months.

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentCoronary DiseaseCoronary AngiographyBalloonAngioplastyInternal medicineCoronary stentmedicineHumansAngina Unstablecardiovascular diseasesMyocardial infarctionAngioplasty Balloon Coronarybusiness.industryStentResidual stenosisMiddle Agedmedicine.diseaseCoronary VesselsSurgerymedicine.anatomical_structureCardiologyStentsCardiology and Cardiovascular MedicineComplicationbusinessArteryCatheterization and Cardiovascular Diagnosis
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Transverse Small Skin Incision for Carotid Endarterectomy

2015

The purpose of this report is to determine the feasibility of short transverse skin incision (STI4 cm) for eversion (EEA) and patch (PEA) endarterectomy with or without shunt by comparing it with the outcomes after long transverse skin incision (LTI 4-8 cm).Of 164 elective consecutive patients (71 ± 2.73% symptomatic) operated at one institution over 24 months, 81 were treated with STI, while 83 patients received LTI. The LTI and STI groups did not differ in terms of age, symptoms, or risk factors. EEA or PEA under locoregional (LRA) or general (GA) anesthesia were performed.STI was associated with shorter operation times (75.19 ± 15.33 vs. 94.87 ± 41 and 99.4 ± 27.36 vs. 132.66 ± 51.32, re…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentDermatologic Surgical ProceduresOperative TimeMedizinCarotid endarterectomyAnesthesia Generalurologic and male genital diseasesSeverity of Illness IndexCicatrixGermanyHumansMedicineCarotid StenosisParesthesiaEndarterectomy CarotidSkin incisionbusiness.industryGeneral Medicinefemale genital diseases and pregnancy complicationsSurgeryTreatment OutcomeFeasibility StudiesSurgeryCardiology and Cardiovascular MedicineComplicationbusinessAnesthesia LocalAnnals of Vascular Surgery
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A new thrombectomy catheter device (AngioJet) for the disruption of thrombi: An in vitro study

1999

In this study we examined a new thrombectomy catheter device. Different kinds of in vitro generated thrombi and cadaver thrombi were disrupted in test tubes. The mean disruption rate (and disruption time for 1 g of thrombus) was 225 +/- 65 mg/sec (5 +/- 2 sec) for whole-blood, 117 +/- 60 mg/sec (12 +/- 9 sec) for fibrin, 41 +/- 18 mg/sec (30 +/- 18 sec) for mixed, 70 +/- 42 mg/sec (17 +/- 5 sec) for unorganized, 45 +/- 8 mg/sec (22 +/- 4 sec) for partly, and 5 +/- 1 mg/sec (216 +/- 29 sec) for completely organized cadaver thrombi (P0.05). More than 99% of fragmented particles of whole-blood thrombi were 0-12 microm in diameter. The particle size of fibrin, mixed, and cadaver thrombi was sim…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentIn Vitro TechniquesFibrinCatheterizationCadavermedicineHumansRadiology Nuclear Medicine and imagingParticle SizeThrombusThrombectomybiologybusiness.industryCatheter deviceThrombosisEquipment DesignGeneral MedicineThrombolysismedicine.diseaseThrombosisPulmonary embolismSurgerymedicine.anatomical_structureEmbolismbiology.proteinPulmonary EmbolismCardiology and Cardiovascular MedicineNuclear medicinebusinessArteryCatheterization and Cardiovascular Interventions
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