Search results for "TIMI"

showing 10 items of 4651 documents

Il Tesoro della Matrice Nuova di Castelbuono nella Contea dei Ventimiglia

2005

Il prezioso e in gran parte inedito corpus di suppellettili argentee della Chiesa Madre di Castelbuono, legato alla committenza della famiglia Ventimiglia analiticamente indagata, viene schedato secondo la più attuale metodologia catalografica e storico critica. La monografia è compendiata da un catalogo dove ciascun manufatto è descritto e contestualizzato nella temperie stilistica di riferimento, evidenziando le influenze artistiche nazionali ed internazionali. La rassegna di opere d’arte proposte nel volume copre un arco cronologico che va dal 1338 al XIX secolo. Vengono inoltre suggerite linee guida per una eventuale musealizzazione

tesoromatricecastelbuonoventimigliaoreficeriaargenteriaarti decorative
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Formation structure of optimality by thermoeconomics: disassembling thermodynamic and external influences in energy systems’ design

2009

In this paper an original thermoeconomic approach for the optimization of complex energy systems is presented, based on a revitalized concept of “scope”, and therefore indicated as Scope Oriented Thermoeconomics (SOT). In plants including dissipative components, it allows to formulate non-arbitrary allocation criteria as concerns marginal costs; consequently, the optimization process is disassembled to recognize the Formation Structure of Optimality, i.e. the specific influences of thermodynamic and economic parameters in the path toward the optimal design. The method is applied to a very didascalic example, that is the optimization of the condensation temperature in a vapour compression ch…

thermoeconomics optimization scope energy systems design productive structure
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Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives

2014

A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…

thiopheneVLAK protocolStereochemistryIn silicoCellAntineoplastic AgentsMechanism of actionHeLa CellHeLaAntineoplastic AgentStructure-Activity Relationship3-Benzoylamino-5-imidazol-4-yl-benzo[b]Settore BIO/10 - BiochimicaDrug DiscoverymedicineHumansMoietyComputer SimulationMitosisCell ProliferationPharmacologyAntitumor agentsbiologyDose-Response Relationship DrugMolecular StructureChemistryDrug Discovery3003 Pharmaceutical ScienceMedicine (all)Cell CycleOrganic ChemistryAntitumor agentG2/M phaseGeneral MedicineSettore CHIM/06 - Chimica OrganicaHeLa cell linebiology.organism_classificationSettore CHIM/08 - Chimica Farmaceuticamedicine.anatomical_structureCell cultureSettore CHIM/03 - Chimica Generale E InorganicathiophenesAntimitotic AgentTopoisomerase-II InhibitorDrug Screening Assays AntitumorHeLa CellsHuman
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Le rôle des outils de mesure de la performance environnementale : le cas des audits et indicateurs environnementaux dans dix entreprises françaises c…

2009

International audience; La performance environnementale est un sujet d'actualité pour les chercheurs en sciences de gestion. Depuis la loi NRE, elle constitue l'une des préoccupations majeures des dirigeants d'entreprises. Pour évaluer cette performance, ceux-ci sont de plus en plus nombreux à adopter des outils de gestion préconisés par les normes ISO 14000, tels que les audits et les indicateurs environnementaux. Il convient alors de s'interroger sur le rôle de ces outils dans les entreprises : répondent-ils à de réels besoins organisationnels ? Ou sont-ils utilisés pour promouvoir l'image des entreprises face aux contraintes institutionnelles de plus en plus fortes ? Cet article tente de…

théorie néo-institutionnellelégitimité socialeperformance environnementalestakeholders environnementauxContrôle de gestion environnementalnéo-institutionnalismesystème de management environnementallégitimité socialenéo-institutionnalismeauditsindicateursContrôle de gestion environnemental[SHS.GESTION]Humanities and Social Sciences/Business administrationlégitimité[SHS.GESTION] Humanities and Social Sciences/Business administrationaudits[ SHS.GESTION ] Humanities and Social Sciences/Business administrationindicateurs
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Multidisciplinary Design Optimization in an integrated CAD/FEM environment

2008

tietokoneavusteinen suunnittelumonitieteisyysoptimointiModeFRONTIERdesignCADCAEMDOmuotooptimizationCAPRImultidisciplinary
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Ekstrēmu uzdevumi par kastēm un to pakošanu

2020

Darbā ir aplūkoti divu tipu ekstrēmu uzdevumi saistībā ar kastēm: klasiskā tipa uzdevums par kastes tilpuma maksimizāciju, pastāvot zināmiem ierobežojumiem, un kombinatoriskās ģeometrijas uzdevums par kvadrātveida kastes maksimālo aizpildījumu jeb blīvāko pakojumu ar uzdota veida figūrām. Uzdevumu risināšanā un grafisku attēlu iegūšanā izmantotas gan iebūvētās funkcijas programmu paketē MATLAB R2015a, gan arī izstrādāts programmas kods, kas paredzēts tetramino N pakošanas problēmas risināšanai.

tilpumsblīvākais pakojumsMatemātikatetraminopoliminooptimizācija
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Regularizācijas filtru salīdzinošā analīze 3D konstrukciju topoloģijas optimizācijai

2015

Darbs ir veltīts topoloģijas optimizācijas izpētei un tās regulējošo filtru salīdzinošai analīzei, izmantojot 3D konstrukcijas. Darbā tiek apskatīti divi filtri – jūtīguma filtrs un Gausa filtrs. Ar matemātiskām metodēm tiek aprēķinātas filtru rādītās izmaiņas konstrukcijā, ja tiek mainīti filtru parametri. Darba galvenais mērķis ir izpētīt šos divus filtrus un veikt to salīdzinošo analīzi, vērtējot filtru darbības precizitāti, rēķināšanas laiku un mērķa funkcijas minimālās vērtības. Darbā tiek apskatīti vairāki 3D konstrukciju piemēri, piemēram, Rīgas dzelzceļa tilts. Tika iegūti rezultāti, kas nākotnē tiks izmantoti topoloģijas optimizācijas regularizācijas filtru plašākai izpētei un piel…

topoloģiskā optimizācijaregularizācija3D konstrukcijasGausa filtrsjūtīguma filtrsMatemātika
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Data from: Optimizing management to enhance multifunctionality in a boreal forest landscape

2016

1. The boreal biome, representing approximately one third of remaining global forests, provides a number of crucial ecosystem services. A particular challenge in forest ecosystems is to reconcile demand for increased timber production with provisioning of other ecosystem services and biodiversity. However, there is still little knowledge about how forest management could help solve this challenge. Hence, studies that investigate how to manage forests to reduce trade-offs between ecosystem services and biodiversity are urgently needed to help forest owners and policy-makers take informed decisions. 2. We applied seven alternative forest management regimes using a forest growth simulator in a…

trade-offsforest planningtimbercarbonmultiobjective optimizationecosystem servicesFinlandclimate change mitigationbiodiversity
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Improving the Effect of Transcranial Alternating Current Stimulation (tACS): A Systematic Review

2021

With the development of electrical stimulation technology, traditional transcranial alternating current stimulation (tACS) technology has been found to have the drawback of not targeting a specific area accurately. Studies have shown that optimizing the number and position of electrodes during electrical stimulation has a very good effect on enhancing brain stimulation accuracy. At present, an increasing number of laboratories have begun to optimize tACS. However, there has been no study summarizing the optimization methods of tACS. Determining whether different optimization methods are effective and the optimization approach could provide information that could guide future tACS research. …

transcranial alternating current stimulationComputer scienceNeurosciences. Biological psychiatry. Neuropsychiatrychemical and pharmacologic phenomenaHuman NeuroscienceReviewhigh definition electrical stimulationintersectional short pulse methodBehavioral NeurosciencePsychiatry and Mental healthstomatognathic diseasesNeuropsychology and Physiological PsychologyNeurologystomatognathic systemBrain stimulationphase-shifted tACSElectronic engineeringOptimization methodstemporally interfering methodBiological Psychiatryamplitude modulated tACSRC321-571Transcranial alternating current stimulationFrontiers in Human Neuroscience
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Transnacionālas ģimenes bērna viktimizācija saistībā ar bērna - aprūpetāja savstarpējo attiecību kvalitāti

2018

Maģistra darba mērķis bija pētīt saistību starp transnacionālas ģimenes bērna viktimizācijas rādītājiem un bērna-aprūpētāja savstarpējo attiecību kvalitāti. Pētījumā piedalījās 304 bērni, vecumā no 11 līdz 18 gadiem. No tiem 34 bija no transnacionālām ģimenēm. Pētījuma dalībnieki aizpildīja šādas aptaujas: Bērnības traumas aptauja, Olveusa pāridarītāju/upuru aptauja. Galvenie secinājumi ir šādi: Bērna-aprūpētāja attiecību kvalitāte ir negatīvi saistīta ar pusaudžu viktimizāciju un vardarbīgu uzvedību. Bērna-aprūpētāja attiecību kvalitāte ir tendenču līmenī saistīta ar transnacionālo ģimeņu pusaudžu viktimizāciju. Viktimizāciju nozīmīgi prognozē bērnu-aprūpētāju attiecību kvalitāte. Vardarbī…

transnacionāla ģimeneviktimizācijaattiecību kvalitātePsiholoģijabērna-aprūpētaja
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