Search results for "TLC"

Dolarización panamericana

2001

Botanical Origin Authentication of Polish Phacelia Honey Using the Combination of Volatile Fraction Profiling by HS-SPME and Lipophilic Fraction Prof…

2019

Eleven samples of Polish Phacelia tanacetifolia Benth., three Brassica napus and one Salix spp. honeys were characterized by melissopalynology and analysis of the compositions of their volatile fractions. Headspace solid-phase microextraction coupled with gas chromatography mass spectrometry (HS-SPME/GC–MS) using PDMS/CAR/DVB fiber was used for the isolation of low-molecular weight compounds which create a volatile fraction. To differentiate and indicate the most representative unifloral samples, chemometric techniques such as principal component analysis (PCA) and hierarchical-tree clustering (HTC) were applied to the dataset of the chromatographic fingerprints. Based on the obtained resul…

Efficient estimation of tuned liquid column damper inerter (TLCDI) parameters for seismic control of base‐isolated structures

2022

This paper presents an enhanced base-isolation (BI) system equipped with a novel passive control device composed of a tuned liquid damper and an inerter (TLCDI). With the aim of reducing the seismic response of BI systems, this contribution focuses on the design of the TLCDI providing analytical solutions for the optimal TLCDI parameters, easily implementable in the design phase. The effectiveness of the proposed approach in terms of seismic response reduction and computational gain is validated by comparison with classical numerical optimization techniques. The control performance of two different base-isolated TLCDI-controlled structures is assessed by employing real-ground motion records…

Numerical and experimental validation of a simplied formulation for the design of TLCD

2013

Chromatographic fingerprint of the volatile fraction of rare Hedera helix honey and biomarkers identification

2018

Hedera helix (Irish ivy) honey is a very rare food product used in Ireland. The composition of the volatile fraction of this unique honey was studied for the first time using three different extraction procedures (SPE, USE and HS–SPME) and analyzed with gas chromatography and mass spectrometry. As expected, the use of combined techniques resulted in the identification of the detailed composition of honey volatiles. Identified constitutes belongs to the different chemical classes. The presence of 4(1H)-quinolinone, myrtenal and phenylacetonitrile was proposed as biomarkers of the botanical origin of ivy honey. Moreover, they are not widely widespread among honeys of different botanical origi…

HPTLC Phenolic Profiles as Useful Tools for the Authentication of Honey

2018

The present study reveals the utility of high-performance thin-layer chromatographic (HPTLC) fingerprinting of phenolic constituents for the authentication of monofloral honeys. The obtained data enables a more complete assessment of honey quality and the identification of emerging threats to honey quality. The developed procedure facilitates differentiation of varietal honeys and detection of honey adulterations. We used an HPTLC fingerprint analysis to determine the characteristic patterns of different honey types (willow, buckwheat, heather, pine honeydew, and manuka honey). The HPTLC chromatograms were used to determine the differences in the botanical origin of the honey samples on the…

Association of Variants in the SPTLC1 Gene with Juvenile Amyotrophic Lateral Sclerosis

2021

Key Points Question What genetic variants are associated with juvenile amyotrophic lateral sclerosis (ALS)? Findings In this family-based genetic study, exome sequencing was performed in 3 patients diagnosed with juvenile ALS and failure to thrive; this identified de novo variants in SPTLC1 (p.Ala20Ser in 2 patients and p.Ser331Tyr in 1 patient). Variants in SPTLC1 are a known cause of hereditary sensory and autonomic neuropathy, type 1A, and these data extend the phenotype associated with this gene. Meaning De novo variants in the SPTLC1 gene are associated with juvenile ALS, a fatal neurological disorder.

Experimental investigation of two-side heat transfer in spacer-filled channels

2020

Abstract In Membrane Distillation (MD), spacers support the membranes and promote mixing, thus reducing temperature polarization. Their efficient design requires a knowledge of the distribution of the local heat transfer coefficient h and of its dependence on Reynolds number, spacer geometry and flow-spacer relative orientation. In previous work, we applied Thermochromic Liquid Crystals (TLC) and digital image processing to the measurement of h distributions for different spacer configurations; data were used to validate CFD simulations and select turbulence models. For constructive reasons, the test section allowed only one-side heat transfer, while in most MD configurations (e.g. spiral-w…

Altérations mitochondriales et processus inflammatoire dans la déficience en acyl- Coenzyme A oxydase 1 peroxysomale

2012

Acyl-CoA oxidase 1 (ACOX1) is the rate-limiting enzyme of the peroxisomal fatty acid β-oxidation pathway of very-long-chain fatty acid (VLCFAs). In humans, ACOX1 deficiency, also called pseudo-neonatal adrenoleukodystrophy, is an autosomal recessive and a severe form of the peroxisomal β-oxidation deficiency. Patients suffer from severe delayed motor development followed by a progressive neurological regression including progressive hypodensity of cerebral white matter, hepatomegaly and deafness and die during late-infantile period. Elevated plasma and tissues VLCFAs levels are detected in these patients. Mice lacking ACOX1 develop severe microvesicular steatohepatitis with increased intrah…

A Novel Mathematical Model For TLCD: Theoretical And Experimental Investigations

2014

In this paper, a novel mathematical model for the Tuned Liquid Column Damper (TLCD) is presented. Taking advantages of fractional derivatives and related concepts, a new equation of motion of the liquid inside the TLCD is obtained. Experimental laboratory tests have been performed in order to validate the proposed linear fractional formulation. Comparison among experimental results, numerical obtained using the classical formulation and numerical with the new linear fractional formulation are reported. Results in frequency domain show how the new linear fractional formulation can predict the real behavior of such a passive vibration control system, more correctly than the classical mathemat…