Search results for "TODIM"
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Type-2 intuitionistic fuzzy TODIM for intelligent decision-making under uncertainty and hesitancy
2022
AbstractThe classical TODIM considers the crisp numbers to handle the information. However, in a real-world applicative context, this information is bounded by noise and vagueness and hence uncertain. There are wide range of works in the literature which utilizes fuzzy sets to handle the uncertainty in the various dimensions. However, there is a constraint of hesitancy in such decision-making problems due to the involvement of various decision-makers. Also, in the TODIM method, decision-maker’s bounded rationality and psychological behavior are also taken into consideration which adds up the hesitation and considers the problem with higher dimension of uncertainty. There are various applica…
Intra- and extra-cellular DNA damage by harmine and 9-methyl-harmine
2014
It is known that b-carbolines are able to produce photosensitized damage in cell-free DNA, but there is little information on their effects on cellular DNA. Therefore, we have analyzed the DNA damage produced by harmine and 9-methyl-harmine under UVA irradiation in V79 cells, together with the associated generation of micronuclei and photocytotoxicity. The results indicate that the most frequent photoproducts generated in the cellular DNA are modified purines such as 8-oxo-7,8-dihydroguanine. Only relatively few single-strand breaks were observed. CPDs were absent, although they were generated in cell-free DNA irradiated under the same conditions. The overall extent of DNA damage in the cel…