Search results for "TOES"
showing 10 items of 134 documents
Modulation of La Crosse virus infection in Aedes albopictus mosquitoes following larval exposure to coffee extracts
2013
This commentary highlights key points, basic ideas, and future outlooks presented by Eastep et al. (2012) in Frontiers in Physiology-Systems Biology. The authors have provided an interesting investigation about the successful use of an environmentally friendly product derived from plants as a larvicidal agent to control mosquito populations as well as a substance that could alter the vector competence of mosquitoes for arthropod-borne viruses (arboviruses). Specifically Eastep and collaborators used coffee extracts (with and without caffeine) to try to answer two hypothesis: first, coffee extracts could have good results as a mosquitocidal compounds applied in larval biotopes and second, vi…
Contribution to the knowledge of the mosquitoes in the Devesa of Racó de l Olla, Albufera Natural Park of Valencia (Spain)
2017
[ES] Se presenta una recopilación de los resultados de varios proyectos, desarrollados entre los años 2004 y 2015, sobre la presencia de los mosquitos de la familia Culicidae en el entorno de la Devesa y el Racó de l¿Olla del Parque Natural de l¿Albufera de Valencia (España). Se registró un total de 10 especies pertenecientes a cinco géneros (Aedes, Coquillettidia, Culex, Culiseta y Ochlerotatus), alguno de estos muy característicos de los ambientes donde fueron recolectados. Se tratan diferentes aspectos sobre la diversidad de culícidos, así como del interés ecológico y sanitario de la presencia de los mismos. Destacamos la existencia de la especie Aedes albopictus (Skuse, 1894) en un espa…
Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus.
2021
Soya consumption can decrease oxidative stress in animal models. Moreover, phytoestrogens such as genistein, present in soya, can mimic some of the beneficial effects of estrogens and are devoid of significant side effects, such as cancer. In this study, we have performed a controlled lifelong study with male OF1 mice that consumed either a soya-free diet or a soya-rich diet. We show that, although we found an increase in the expression and activity of antioxidant enzymes in soya-consuming mice, it did not increase lifespan. We reasoned that the soya diet could not increase lifespan in a very healthy population, but perhaps it could extend health span in stressed animals such as type 2 diab…
Input of P, N-(phosphanyl, amino)-ferrocene hybrid derivatives in late transition metals catalysis
2018
International audience; Unequally functionalized ferrocenes give access to valuable hemilabile reactivity in catalytic reaction. We address the synthesis of hybrid (P, N)-ferrocenyl compounds for which recent catalytic breakthrough applications have been reported, transversely in late transition metals chemistry. Palladium, nickel, rhodium, iridium, and emerging iron and gold catalysis are illustrated from selected examples, which include CC bond formation from cross-coupling and polymerization, allylic substitution, cyanation, hydroformylation, CH arylation and silylation and hydrogenation reactions.
Genistein effect on cognition in prodromal Alzheimer's disease patients : the GENIAL clinical trial
2022
Background: Delaying the transition from minimal cognitive impairment to Alzheimer’s dementia is a major concern in Alzheimer’s disease (AD) therapeutics. Pathological signs of AD occur years before the onset of clinical dementia. Thus, long-term therapeutic approaches, with safe, minimally invasive, and yet efective substances are recommended. There is a need to develop new drugs to delay Alzheimer’s dementia. We have taken a nutritional supplement approach with genistein, a chemically defned polyphenol that acts by multimodal specifc mechanisms. Our group previously showed that genistein supplementation is efective to treat the double transgenic (APP/PS1) AD animal model. Methods: In this…
New findings on the bioactivity of lignans
2002
Abstract This chapter reviews the lignans with biological and pharmacological activity, and includes new natural products and some synthetic or semisynthetic compounds. Lignans are widespread in plants and in many cases are their effective principles. They play an important role as phytoestrogens in preventing menopausial symptoms, osteoporosis, cancer and heart diseases. Lignans possess anticancer and antiviral properties and specifically inhibit certain enzymes and mediators involved in inflammation and immunity processes. They affect the cardiovascular system by different mechanisms including the modification of phosphodiesterase activity and platelet activating factor function. Lignans …
Risk factors for being a victim of online grooming in adolescents
2020
The risk of child grooming has spread exponentially with the massive access of adolescents to social networks and the internet. The aim of the study was to examine the personal factors (body self-esteem and disinhibition) and erotic-sexual factors (sexual initiation strategies and erotic-pornographic sexting) that predict grooming. METHOD: The sample was comprised of 1,200 adolescents aged between 12 and 16 years (M = 14.54, SD = 1.17; 50.83% girls). A cross-sectional design with self-report data was used and structural equation modeling (SEM) with mediation analysis was performed. RESULTS: The results indicated two paths explaining child grooming: 1) physical attractiveness and disinhibiti…
Implementación y evaluación de la eficacia de un Programa de Educación Emocional en Adolescentes con diagnóstico de TDAH
2019
Las habilidades socioemocionales en jóvenes con diagnóstico de Trastorno por Déficit de Atención e Hiperactividad (TDAH) son esenciales en su desarrollo psicológico y bienestar personal. Sin embargo, a pesar del reconocimiento general de la necesidad de dotar a estos jóvenes de recursos y estrategias que no están ni atendidas ni contempladas en el currículo académico, son escasos los trabajos que muestren la validez de programas de educación emocional en este colectivo. El objetivo del trabajo fue triple: a) la adaptación e implementación de un programa de educación emocional (denominado INTEMO), b) la evaluación de su eficacia, y c) el análisis de la satisfacción con el programa de usuario…
El uso problemático del smartphone y la autoestima: un meta-análisis
2023
El uso problemático del smartphone ha sido catalogado como un problema de salud pública por la Organización Mundial de la Salud. El objetivo del presente trabajo es examinar la relación entre el uso problemático del smartphone y la autoestima. Se realizó una búsqueda bibliográfica en las bases de datos PsycInfo, PubMed y Scopus recuperando un total de 30 estudios relevantes con una muestra total de 20916 participantes. El tamaño del efecto obtenido mediante un modelo de efectos aleatorios es significativo y negativo (r = -.25; IC 95% = -.28, -.21), por lo que las personas que poseen una menor autoestima, presentan mayores niveles de uso problemático del smartphone. Los análisis de meta-regr…
Efectos de la exposición crónica al etanol sobre el tráfico intracelular y citoesqueleto como factores implicados en la migración neuronal
2013
El consumo de etanol durante la gestación puede inducir una serie de alteraciones graves en el desarrollo del feto, la manifestación más extrema da lugar al Síndrome Alcohólico Fetal (SAF). La exposición prenatal al alcohol es la causa conocida y, además evitable, más importante de retraso mental en el mundo occidental. Además de déficits cognitivos, los niños con SAF presentan múltiples anomalías estructurales en el sistema nervioso central, como reducción de la masa cerebral, y a nivel celular, daños en la migración neuronal, en el proceso de formación de espinas dendríticas y establecimiento de sinapsis. En la actualidad, los mecanismos moleculares implicados en la teratogénesis inducida…