Search results for "TOOL"

Dinamiche di popolamento e processi di trasmissione culturale nel comprensorio madonita attraverso la ricostruzione della viabilità antica

2020

La ricerca sulle Madonie nasce con l’intenzione di approfondire l’evoluzione storica del popolamento sulla regione montana della Sicilia nord-occidentale. Il territorio, che solo in anni recenti è divenuto oggetto di più approfondite ricerche storico-archeologiche, si presenta estremamente ricco di risorse naturali e caratterizzato da un sostrato culturale variegato che abbraccia territori d’alta montagna, dediti ad una economia silvo-pastorale prettamente conservativa, e insediamenti costieri fortemente proiettati allo scambio e al commercio. A fine di comprendere lo sviluppo delle dinamiche d’insediamento di un’area molto estesa, si è proceduto anzitutto con la restituzione ipotetica dei …

Experimental and numerical analysis on post welding formability of FSWed AZ31 magnesium alloy thin joints obtained using a "Pinless" tool configurati…

2012

The post welding formability of friction stir welded AZ31 magnesium alloy thin sheets (1.5 mm thick), obtained using a “pinless” tool configuration, was widely investigated by means of the hemispherical punch method at 350°C, with a constant crosshead speed of 0.1 mm/s. The results were compared with those obtained on the base material. It has shown that formability of the joints is lower than the one of the base material. The experimental work was supported by a numerical investigation based on FEM in order to highlight the material flow occurring during the welding process. Additionally, hemispherical punch tests were simulated starting from the calculated conditions, in terms of accumula…

Experimental and numerical analysis on FSWed magnesium alloy thin sheets obtained using “pin” and “pinless” tool

2012

A new family with an SLC9A6 mutation expanding the phenotypic spectrum of Christianson syndrome

2016

Using targeted next generation sequencing, we have identified a splicing mutation (c.526-9_526-5del) in the SLC9A6 gene in a 9-year-old boy with mild intellectual disability (ID), microcephaly, and social interaction disabilities. This intronic microdeletion leads to the skipping of exon 3 and to an in-frame deletion of 26 amino acids in the TM4 domain. It segregates with cognitive impairment or learning difficulties in other members of the family. Mutations in SLC9A6 have been reported in X-linked Christianson syndrome associating severe to profound intellectual deficiency and an Angelman-like phenotype with microcephaly, absent speech, ataxia with progressive cerebellar atrophy, ophthalmo…

Intestinal symptoms and Blastocystis load in schoolchildren of Paranaguá Bay, Paraná, Brazil

2017

ABSTRACT The symptomatology of Blastocystis cannot be attributed to any particular subtype, although can be related to a high Blastocystis infection load. One stool sample from each of 217 schoolchildren of Vale de Sol Paranaguá Bay (Paraná, Brazil) was collected. Three milliliters of each fixed stool sample were processed applying the formalin-ether concentration technique. After obtaining the overall prevalence of intestinal parasites, quantification was carried out in Blastocystis positive samples. A total of 75/217 (34.6%) children suffered from intestinal symptoms (abdominal pain and/or persistent diarrhea), of whom 41.3% (31/75) presented moderate/heavy Blastocystis load with a statis…

A combined therapy for limb apraxia and related anosognosia.

2019

Left hemisphere stroke frequently leads to limb apraxia, a disorder that has been reported to impact independence in daily life and rehabilitation success. Nonetheless, there is a shortcoming in research and availability of applicable trainings. Further, to date, anosognosia for limb apraxia has largely been neglected. Therefore, we developed a Naturalistic Action Therapy that trains object selection and application with an errorless learning approach and which includes supported self-evaluation. The current study presents the results of two stroke patients participating in the training. The procedure entailed two baseline and one post-training sessions including standardized limb apraxia a…

Application of screening tools to detect risk of hospital readmission in elderly patients in Valencian Healthcare System (VHS) (Spain).

2013

Abstract The Sustainable Social and Healthcare Model (SSHM) is aimed to establish new care pathways in primary care systems contributing to the decrease of health services use and costs and improve the integration and efficiency of social and health care for elderly people with long-term care (LTC) needs. One of these strategies is the segmentation of population in risk groups through standardized tools. This paper is a retrospective study aimed to determine the viability of the implementation of the screening tools Probability of Repeated Admission – Pra – and The Community Assessment Risk Screen – CARS – to detect patients at risk of hospital readmission in a sample of 500 elderly people …

Development and reliability of a streetscape observation instrument for international use: MAPS-global

2018

Background: Relationships between several built environment factors and physical activity and walking behavior are well established, but internationally-comparable built environment measures are lacking. The Microscale Audit of Pedestrian Streetscapes (MAPS)-Global is an observational measure of detailed streetscape features relevant to physical activity that was developed for international use. This study examined the inter-observer reliability of the instrument in five countries. Methods: MAPS-Global was developed by compiling concepts and items from eight environmental measures relevant to walking and bicycling. Inter-rater reliability data were collected in neighborhoods selected to var…

Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans.

2011

One major expectation from the transcriptome in humans is to characterize the biological basis of associations identified by genome-wide association studies. So far, few cis expression quantitative trait loci (eQTLs) have been reliably related to disease susceptibility. Trans-regulating mechanisms may play a more prominent role in disease susceptibility. We analyzed 12,808 genes detected in at least 5% of circulating monocyte samples from a population-based sample of 1,490 European unrelated subjects. We applied a method of extraction of expression patterns—independent component analysis—to identify sets of co-regulated genes. These patterns were then related to 675,350 SNPs to identify maj…

Does pain intensity predict a poor opioid response in cancer patients?

2011

Abstract Aim The aim of this study was to test the hypothesis that initial pain intensity is not a predictive factor of poor opioid response in advanced cancer patients, as suggested by a recent work. Methods A secondary analysis of one-hundred-sixty-seven patients referred for treatment of cancer-related pain was conducted. Pain intensity at admission was recorded and patients were divided in three categories of pain intensity: mild, moderate and severe. Patients were offered a treatment with opioid dose titration, according to department policy. Data regarding opioid doses and pain intensity were collected after dose titration was completed. Four levels of opioid response were considered:…