Search results for "TOPOGRAPHY"

showing 10 items of 144 documents

Tolerability of 24-hour intraocular pressure monitoring of a pressure-sensitive contact lens.

2013

Purpose To investigate tolerability and safety of a new diagnostic device for 24-hour intraocular pressure monitoring in healthy subjects and age-matched glaucoma patients. Patients and methods Twenty healthy subjects (group 1) and 20 age-matched glaucoma patients (group 2) were included in this prospective, single-center, open, observational parallel group study. The SENSIMED Triggerfish Sensor is a soft disposable contact lens embedding a telemetry chip and strain gauge sensor for continuous intraocular pressure monitoring. The Sensor was placed in 1 eye for 24 hours. Tolerability was evaluated using a visual analog scale (range, 0 to 100; 0=no discomfort; 100=very severe discomfort). Saf…

AdultMaleIntraocular pressuremedicine.medical_specialtygenetic structuresCorneal PachymetryVisual analogue scaleVisual AcuityGlaucomaMonitoring AmbulatoryTonometry OcularOphthalmologyMedicineHumansTelemetryProspective StudiesCorneal pachymetryProspective cohort studyIntraocular PressureAgedmedicine.diagnostic_testEquipment Safetybusiness.industryCorneal TopographyGlaucomaMiddle Agedmedicine.diseaseCorneal topographyContact Lenses Hydrophiliceye diseasesCircadian RhythmContact lensOphthalmologyTolerabilityPatient SatisfactionFemalebusinessJournal of glaucoma
researchProduct

Corneoscleral contact lenses for visual rehabilitation after keratoplasty surgery.

2019

Abstract Purpose To report the use of corneoscleral lenses (CSL) in keratoconus patients who were unsatisfied with their visual outcomes after keratoplasty surgery. Methods Eleven consecutive cases with unsatisfactory vision with spectacles, due to irregular astigmatism, preferred to try CSL before SL due to handling or economic issues. An eye examination included refraction and visual acuity assessment, anterior eye biomicroscopy, ocular fundus examination, corneal topographic analysis, endothelial-cell count (ECC) and evaluation of corneal biomechanical parameters (corneal resistance factor, CRF; corneal hysteresis, CH; corneal-compensated intraocular pressure, IOPcc). The fitting process…

AdultMaleKeratoconusIntraocular pressuremedicine.medical_specialtyVisual acuitygenetic structuresContact LensesVisual rehabilitationKeratoconusRefraction Ocularlaw.inventionCorneal hysteresisCorneal Transplantation03 medical and health sciences0302 clinical medicinelawmedicineHumansAgedRetrospective StudiesAged 80 and overKeratometerIrregular astigmatismmedicine.diagnostic_testbusiness.industryAstigmatismCorneal TopographyGeneral MedicineMiddle Agedmedicine.diseaseeye diseasesSurgeryOphthalmologyEye examination030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryKeratoplasty PenetratingOptometryContact lensanterior eye : the journal of the British Contact Lens Association
researchProduct

A new approach based on Machine Learning for predicting corneal curvature (K1) and astigmatism in patients with keratoconus after intracorneal ring i…

2014

Keratoconus (KC) is the most common type of corneal ectasia. A corneal transplantation was the treatment of choice until the last decade. However, intra-corneal ring implantation has become more and more common, and it is commonly used to treat KC thus avoiding a corneal transplantation. This work proposes a new approach based on Machine Learning to predict the vision gain of KC patients after ring implantation. That vision gain is assessed by means of the corneal curvature and the astigmatism. Different models were proposed; the best results were achieved by an artificial neural network based on the Multilayer Perceptron. The error provided by the best model was 0.97D of corneal curvature …

AdultMaleKeratoconusgenetic structuresComputer sciencemedicine.medical_treatmentHealth InformaticsAstigmatismMachine learningcomputer.software_genreKeratoconusCorneal TransplantationMachine LearningYoung AdultCorneal ectasiaIntracorneal ringsArtificial IntelligenceProsthesis FittingmedicineHumansIn patientCorneal transplantationAgedRing (mathematics)Corneal curvaturebusiness.industryCorneal TopographyAstigmatismProstheses and ImplantsMiddle AgedDecision Support Systems ClinicalPrognosismedicine.diseaseeye diseasesComputer Science ApplicationsPatient Outcome AssessmentTreatment OutcomeFemalesense organsArtificial intelligencebusinesscomputerLENGUAJES Y SISTEMAS INFORMATICOSSoftware
researchProduct

Evaluation of the anterior chamber angle in keratoconus and normal subjects.

2015

To evaluate the anterior chamber angle in keratoconus eyes by use of the Visante™ OCT and Orbscan™ II.Anterior chamber angle was measured with the Visante™ OCT and Orbscan™ II in 52 subjects, 26 KC subjects and 26 age and control subjects.When comparing the nasal and temporal angles obtained with the two techniques no correlation was found (R(2) always below 0.01) in either the control subjects or in the KC subjects. Despite this, there was an overall statistically significant difference in mean anterior chamber angles (p0.001) between Visante™ OCT and Orbscan™ II. There was no statistical difference (p0.05) between nasal and temporal anterior chamber angles when comparing controls and KC s…

AdultMaleKeratoconusmedicine.medical_specialtyKeratoconusSensitivity and SpecificityAnterior chamber angleAnterior Eye SegmentReference ValuesOphthalmologymedicineHumansOrbscan iiSlit Lampbusiness.industrySignificant differenceCorneal TopographyReproducibility of ResultsGeneral Medicinemedicine.diseaseControl subjectsOphthalmologyOptometryFemalebusinessTomography Optical CoherenceOptometryContact lensanterior eye : the journal of the British Contact Lens Association
researchProduct

Intrastromal corneal ring segment implantation in paracentral keratoconus with coincident topographic and coma axis.

2012

To evaluate the efficacy, predictability, and safety of implantation of Ferrara-type intrastromal corneal ring segments (ICRS) for refractive correction of paracentral keratoconus.Fernández-Vega Ophthalmological Institute, Oviedo, Spain.Cohort study.Snellen uncorrected (UDVA) and corrected (CDVA) distance visual acuities and residual refractive errors were recorded before and 6 months after ICRS implantation for keratoconus. The tunnels for ICRS implantation were created with a femtosecond laser. The power vector and the Alpins method were used to analyze postoperative refractive outcomes.The study evaluated 56 eyes of 49 patients. The mean UDVA was 0.17 ± 0.14 (SD) preoperatively and 0.41 …

AdultMaleKeratoconusmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentCorneal StromaVision DisordersVisual AcuityComa (optics)Power vectorKeratoconusRefraction OcularCohort StudiesProsthesis ImplantationYoung AdultOphthalmologymedicineHumansPolymethyl MethacrylateProspective StudiesAlpins methodAgedIntrastromal corneal ring segmentbusiness.industryCorneal TopographyProstheses and ImplantsMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologySurgeryFemalesense organsLaser TherapyCorneal ringbusinessJournal of cataract and refractive surgery
researchProduct

High incidence and increasing prevalence of MS in Enna (Sicily), southern Italy

2001

Twenty years after a first survey, a follow-up study was performed on the prevalence of MS in Enna (Sicily), southern Italy. The prevalence of definite MS rose from 53 to 120.2 per 100,000 population. The incidence of definite MS for the period 1986 to 1995 was 5.7 per 100,000 per year. The innermost part of Sicily shows an elevated prevalence of MS, second only to Sardinia in the Mediterranean area.

AdultMaleMultiple SclerosisAdolescentCross-sectional studyPopulationHumansChildeducationSicilyAgededucation.field_of_studyNeuroscience (all)IncidenceIncidence (epidemiology)Follow up studiesMiddle AgedHealth SurveysCross-Sectional StudiesGeographyMediterranean areaFemaleTopography MedicalSettore MED/26 - NeurologiaNeurology (clinical)High incidenceFollow-Up StudiesDemography
researchProduct

Iris-fixated toric phakic intraocular lens for myopic astigmatism

2011

Purpose To evaluate the efficacy, predictability, safety, stability, and complications of the Artiflex toric iris-fixated phakic intraocular lens (pIOL) for myopic astigmatism. Setting Private practice surgery centers, Valencia and Terrassa, Spain. Design Cohort study. Methods At 12 months, refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, complications, pIOL misalignment, and endothelial cell count (ECC) were evaluated. Indices of success and misalignment were calculated using vector analysis. Results The study enrolled 42 eyes in 25 patients aged 21 to 39 years. The mean spherical equivalent decreased from −8.85 diopters (D) ± 2.71 (SD) to −0.37 ± 0.46 D, with …

AdultMalePhakic Intraocular Lensesmedicine.medical_specialtyVisual acuitygenetic structuresVisual AcuityIrisAstigmatismRefraction OcularPhakic intraocular lensCohort StudiesMyopic astigmatismYoung AdultPostoperative ComplicationsLens Implantation IntraocularOphthalmologyMyopiamedicineHumansIris (anatomy)Dioptremedicine.diagnostic_testbusiness.industrySuture TechniquesAstigmatismCorneal TopographyCorneal topographymedicine.diseaseeye diseasesSensory SystemsOphthalmologyTreatment Outcomemedicine.anatomical_structurePrivate practiceFemaleSurgerymedicine.symptombusinessFollow-Up StudiesJournal of Cataract and Refractive Surgery
researchProduct

The applicability of SRTM in [18F]fallypride PET investigations: Impact of scan durations

2011

The high-affinity radioligand [18F]fallypride (FP) is frequently used for quantification of striatal/extrastriatal D2/3 receptors and the receptor occupancies of antipsychotics (APs). Its 110 minutes half-life allows long scan durations. However, the optimum scan duration is a matter of debate. This investigation focuses on scan-duration-related effects on simplified reference tissue model (SRTM) results and the time point of transient equilibrium in a large sample of dynamic FP positron emission tomography (PET) scans. Fifty drug-free and 50 AP-treated subjects underwent FP-PET scans (180 minutes scan duration). The binding potential ( BPND) of the putamen, thalamus, and temporal cortex w…

AdultMalePyrrolidinesTime FactorsMaterials scienceAdolescentShuttle Radar Topography MissionRadioligand AssayYoung AdultRadioligandmedicineHumansTemporal cortexTransient equilibriummedicine.diagnostic_testReceptors Dopamine D2business.industryMental DisordersPutamenReceptors Dopamine D3Binding potentialMiddle AgedCorpus StriatumNeurologyFallypridePositron emission tomographyPositron-Emission TomographyBenzamidesFemaleOriginal ArticleNeurology (clinical)Cardiology and Cardiovascular MedicineNuclear medicinebusinessAntipsychotic AgentsJournal of Cerebral Blood Flow & Metabolism
researchProduct

Characterization of the effect of intracorneal ring segment in corneal ectasia after laser refractive surgery

2018

Purpose: To evaluate the visual, refractive, topographic, pachymetric, and biomechanical outcomes after intracorneal ring segment implantation in corneas with post-LASIK ectasia. Methods: Retrospective longitudinal study enrolling 26 eyes of 22 patients with post-LASIK ectasia and undergoing intracorneal ring segment implantation (KeraRing®, Mediphacos) using a 60-kHz femtosecond laser (IntraLase®, IntraLase Corp.) for corneal tunnelization. Visual, refractive, anterior, and posterior corneal topographic (Pentacam HR, Oculus), pachymetric, and corneal biomechanical changes (Ocular response Analyzer, Reichert) were evaluated during a 12-month follow-up. Vector analysis of astigmatic changes …

AdultMaleReoperationmedicine.medical_specialtyCorneal ectasiagenetic structuresCorneal Surgery Lasermedicine.medical_treatmentVisual AcuityAstigmatismProsthesis DesignRefraction OcularCorneal Diseaseslaw.inventionCorneaCorneal ectasiaPostoperative ComplicationsLens Implantation IntraocularlawIntracorneal ring segmentEctasiaOphthalmologyRefractive surgerymedicineHumansPost-LASIK ectasiaPentacam hrIntracorneal ring segmentRetrospective StudiesÓpticaPost-LASIK ectasiabusiness.industryCorneal TopographyGeneral MedicineMiddle Agedmedicine.diseaseLasereye diseasesOphthalmologyFemalesense organsbusinessDilatation PathologicFollow-Up StudiesEuropean Journal of Ophthalmology
researchProduct

The anisotropy of personal space.

2019

Violations of personal space are associated with discomfort. However, the exact function linking the magnitude of discomfort to interpersonal distance has not yet been specified. In this study, we explore whether interpersonal distance and discomfort are isotropic with respect to uncomfortably far or close distances. We also extend previous findings with regard to intrusions into personal space as well as maintenance of distances outside of personal space. We presented subjects with 15 interpersonal distances ranging from 40 to 250 cm and obtained verbal and joystick-based ratings of discomfort. Whereas discomfort rose immediately when personal space was entered, the gradient was less steep…

AdultMaleResearch ValidityTopographyScienceMaterials ScienceMaterial PropertiesEmotionsSocial SciencesResearch and Analysis MethodsStatistical InferencePersonal SpaceYoung AdultMathematical and Statistical TechniquesTask Performance and AnalysisPsychologyHumansStatistical MethodsStatistical DataAnalysis of VarianceLandformsBehaviorPhysicsStatisticsQRBiology and Life SciencesReproducibility of ResultsGeomorphologyFearResearch AssessmentMiddle AgedCondensed Matter Physics150 PsychologiePhysical SciencesEarth SciencesAnisotropyMedicineFemale150 PsychologyMathematicsResearch ArticleValleysPLoS ONE
researchProduct