Search results for "TOPS"
showing 10 items of 398 documents
District metered area design through multicriteria and multiobjective optimization
2022
[EN] The design of district metered areas (DMA) in potable water supply systems is of paramount importance for water utilities to properly manage their systems. Concomitant to their main objective, namely, to deliver quality water to consumers, the benefits include leakage reduction and prompt reaction in cases of natural or malicious contamination events. Given the structure of a water distribution network (WDN), graph theory is the basis for DMA design, and clustering algorithms can be applied to perform the partitioning. However, such sectorization entails a number of network modifications (installing cut-off valves and metering and control devices) involving costs and operation changes,…
COVID-19 Vaccine and Death: Causality Algorithm According to the WHO Eligibility Diagnosis
2021
The current challenge worldwide is the administration of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Even if rarely, severe vascular adverse reactions temporally related to vaccine administration have induced diffidence in the population at large. In particular, researchers worldwide are focusing on the so-called “thrombosis and thrombocytopenia after COVID-19 vaccination”. This study aims to establish a practical workflow to define the relationship between adverse events following immunization (AEFI) and COVID-19 vaccination, following the basic framework of the World Health Organization (WHO). Post-mortem investigation plays a pivotal role to support this c…
Role of virtopsy in the postmortem diagnosis of drowning
2014
Aims and objectives Methods and materials Results Conclusion Personal information References
Atopidae (Trilobita) in the upper Marianian (Cambrian Series 2, Stage 4) of Iberia
2020
AbstractNew atopid trilobites are described from the early Cambrian Cumbres beds and Herrerías shale of northern Huelva Province (Andalusia, Spain) and are dated as middle–late Marianian (Cambrian Series 2, Stage 4). New specimens ofAtops calanusRichter and Richter, 1941 are described and the Laurentian speciesPseudatops reticulatus(Walcott, 1890b) is recognized for the first time in the Mediterranean subprovince. The associated trilobite assemblage studied herein suggests an age close to the base of Cambrian Stage 4.
Rehabilitation of Mediterranean anthropogenic soils using symbiotic wild legume shrubs: Plant establishment and impact on the soil bacterial communit…
2010
Abstract Susceptibility to desertification in southern Europe is increasing and rehabilitation of desertification-threatened Mediterranean soils is a challenge due to the inhospitality of the environment. In particular, recovery of anthropogenic soils (mainly human-derived artefacts from housing construction and other inert materials or topsoil of terminal phase municipal landfills) cannot rely on spontaneous processes and low-cost/low-impact strategies are needed to prevent desertification. Mediterranean wild legume shrubs have great potential for soil recovery and conservation against desertification, thanks to drought resistance, and their symbiosis with N2-fixing rhizobia and arbuscular…
Effects of parent material on soil erosion within Mediterranean new vineyard plantations
2018
[EN] Parent material can determine specific physical and chemical soil properties and, therefore, soil erosion rates. However, for new vine plantations, there is not enough research on soil erosion assessment on different parent materials which could be helpful for agricultural management plans. The main aim of this research was to quantify soil erosion rates of two recent vineyard plantations under similar climate and land use management conditions, but on different parent materials, namely colluvium (2 years old) and marls (8 years old), located within the Les Alcusses valley vineyards in Eastern Spain. To achieve this goal, the ISUM (improved stock unearthing method) was applied. ISUM in…
Spatial relations of heavy metals in arable and greenhouse soils of a Mediterranean environment region (Spain)
2013
This study characterises and compares Cr, Ni, Pb, Cu, Zn and Cd (HMs) contents and the main edaphic parameters in arable soils (AS) from western areas of the Andalusian Autonomous Community (SE Spain) with greenhouse soils (GS) from the province of Almería, one of the most productive agricultural systems in Europe. We explored 199 GS and 142 AS, representing local and regional scales of variation in this important Mediterranean area. The hazardousness of HMs was particularly relevant in GS where agricultural practices, which centre on maximising production, end up with products that finally enter the human food chain directly. Despite their similar edaphic characteristics, the main differen…
Western Mediterranean Climate Response to Dansgaard/Oeschger Events: New Insights From Speleothem Records
2019
The climate of the western Mediterranean was characterized by a strong precipitation gradient during the Holocene driven by atmospheric circulation patterns. The scarcity of terrestrial paleoclimate archives has precluded exploring this hydroclimate pattern during Marine Isotope Stages 5 to 3. Here we present stable carbon and oxygen isotope records from three flowstones from southeast Iberia, which show that Dansgaard/Oeschger events were associated with more humid conditions. This is in agreement with other records from the Iberian Peninsula, the Mediterranean, and western Europe, which all responded in a similar way to millennial‐scale climate variability in Greenland. This general incre…
Minimizing membrane bioreactor environmental footprint by multiple objective optimization.
2020
This paper presents a modelling study aimed at minimizing the environmental foot print of a membrane bioreactor (MBR) for wastewater treatment. Specifically, an integrated model for MBR was employed in view of the management optimization of an MBR biological nutrient removal (BNR) pilot plant in terms of operational costs and direct greenhouse gases emissions. The influence of the operational parameters (OPs) on performance indicators (PIs) was investigated by adopting the Extended-FAST sensitivity analysis method. Further, a multi-objective analysis was performed by applying the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). The results show-up that the sludge …
3,5-bis(3'-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: synthesis and antitumor properties.
2007
A series of 10 bis-indolylpyrazoles of type 9, 10 were obtained by cyclization of diketones 8 using hydrazine monohydrate or methylhydrazine in refluxing acetic acid/THF. Derivatives 9a,c,d were selected, by the National Cancer Institute (NCI, Bethesda, USA), to be evaluated against the full panel of about 60 human tumor cell lines derived from nine human cancer cell types and showed antiproliferative activity in the micromolar range. In particular, 9d, the most active compound was effective against all the tested cell lines with a GI(50) mean value of 3.23 microM; TGI and LC(50) values were 14.5 and 58.9 microM having positive response on 91% and 41% of the tested cell lines, respectively.