Search results for "TOPS"
showing 10 items of 398 documents
Hronotops un gotiskais šausmu kino
2017
Bakalaura darba „Hronotops un gotiskais šausmu kino” mērķis ir aplūkot laiktelpas dinamiku gotiskā šausmu kino žanrā un apkopot tā raksturiezīmes fiksētas telpas ietveros. Mērķa sasniegšanai tiek izmantota Mihaila Bahtina hronotopa teorija, kura aplūko laiktelpas dinamikas un funkcijas literāro darbu žanros. Pilnvērtīgai analīzei tiek izmantota arī Vladimira Propa tēlu funkciju teorija. Teorētiskā darba daļa sastāv no pētniecisko teoriju apskata, kā arī gotisko romānu un šausmu kino vēsturiskās attīstības aplūkošanas. Analītiskā darba daļa sevī iekļauj izvēlēto filmu hronotopu un tēlu analīzi, balstoties uz to, kā literārās hronotopu kategorijas tiek pielāgotas kino analīzei. Secinājumos ti…
CONGENITAL NEUROBLASTOMA: A RARE CASE OF PLURIVISCERAL METASTATIC DISSEMINATION
2021
Neuroblastoma is one of the most common neonatal tumors. It involves children in early infancy and originates from neural crest cells of the adrenal gland medulla or sympathetic glia. We report an unusual case of congenital poorly differentiated neuroblastoma with multiple metastases in the brain and cerebellum. The biophysical profile showed a prominent polyhydramnios at 25.3 weeks of gestation; meantime, the mother was diagnosed with gestational diabetes. The mass was detected during the third ultrasonographic examination at 31.4 weeks of gestation. The fetus lived only one day after birth and the postmortem examinations were performed subsequently. An autopsy was performed both to unders…
A revision of the Old World species of Leptopsilopa Cresson (Insecta: Diptera: Ephydridae)
2016
Diagnoses and illustrations of three Leptopsilopa species known in the Old World: L. africana Cresson, L. mutabilis Cresson and L. pollinosa (Kertesz) are provided. Three new synonyms are proposed: L. aurata (Canzoneri and Meneghini) and L. tibialis (Canzoneri and Meneghini) = L. africana; Psilopa confeteae Canzoneri and Munari = L. pollinosa. Three other species are removed from Leptopsilopa and combined with Athyroglossa, as A. leonensis (Canzoneri and Rampini), new combination, A. mianii (Canzoneri) new combination and A. rossii (Canzoneri and Raffone), new combination.
NOVEL NORTOPSENTIN ANALOGUES: PYRROLO[2,3-b]PYRIDINE,bis(PYRROLO[2,3-b]PYRIDINE AND 7 -CHLORO-PYRROLO[2,3-c]PYRIDINE ANALOGUES
2014
SYNTHESIS OF PYRROLO[2,3-b]PYRIDINE, BIS(PYRROLO[2,3-b]PYRIDINE) and 7-CHLORO-PYRROLO[2,3-c]PYRIDINE, ANALOGUES OF MARINE BIS(INDOLE)ALKALOID NORTOPS…
2014
Synthesis and biological activity of a new series of nortopsentin analogues
2015
Synthesis of Nortopsentin analogues
2014
Synthesis and antitumor activity of new 7-azaindole derivative nortopsentin analogues
2016
Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in…
2023
Pancreatic ductal adenocarcinoma (PDAC) is one of the main aggressive types of cancer, characterized by late prognosis and drug resistance. Among the main factors sustaining PDAC progression, the alteration of cell metabolism has emerged to have a key role in PDAC cell proliferation, invasion, and resistance to standard chemotherapeutic agents. Taking into account all these factors and the urgency in evaluating novel options to treat PDAC, in the present work we reported the synthesis of a new series of indolyl-7-azaindolyl triazine compounds inspired by marine bis-indolyl alkaloids. We first assessed the ability of the new triazine compounds to inhibit the enzymatic activity of pyruvate de…
Encoding specificity instead of online integration of real-world spatial regularities for objects in working memory
2022
Most objects show high degrees of spatial regularity (e.g. beach umbrellas appear above, not under, beach chairs). The spatial regularities of real-world objects benefit visual working memory (VWM), but the mechanisms behind this spatial regularity effect remain unclear. The "encoding specificity" hypothesis suggests that spatial regularity will enhance the visual encoding process but will not facilitate the integration of information online during VWM maintenance. The "perception-alike" hypothesis suggests that spatial regularity will function in both visual encoding and online integration during VWM maintenance. We investigated whether VWM integrates sequentially presented real-world obje…