Search results for "TOPSIS."

From microbial proteomics to synthetic biology: Amycolatopsis balhimycina case

2012

Actinomycetes, filamentous Gram-positive bacteria, are usually exploited as bio-farms naturally producing a wide range of small biologically active metabolites, such as antibiotics, extensively used in medicine, food-industry, chemistry and bio-remediation strategies. The development of high throughput technologies, like proteomics, allows functional genomic studies aimed at shedding light on molecular mechanisms controlling the production of useful compounds and macromolecules. Differential proteomic analyses, performed by using Two Dimensional PolyAcrylamide Gel Electrophoresis (2D-PAGE) coupled to mass spectrometry (MS) procedures, revealed novel links between balhimycin production (a va…

Sustainable vehicle routing based on firefly algorithm and TOPSIS methodology

2019

Abstract In a sustainable management of logistics, transportation plays a crucial role. Traditionally, the main purpose was to solve the Vehicle Routing Problem minimizing the cost associated with the travelled distances. Nowadays, the economic profit cannot be the only driver for achieving sustainability and environmental issues have to be also considered. In this paper, to satisfy the intricate limits involved in real vehicle routing problem, the study has been structured considering different types of vehicles in terms of maximum capacity, velocity and emissions, asymmetric paths, vehicle-client constraints and delivery time windows. The firefly algorithm has been implemented to solve th…

Decision-Making Tools to Manage the Microbiology of Drinking Water Distribution Systems

2020

[EN] This paper uses a two-fold multi-criteria decision-making (MCDM) approach applied for the first time to the field of microbial management of drinking water distribution systems (DWDS). Specifically, the decision-making trial and evaluation laboratory (DEMATEL) was applied removing the need for reliance on expert judgement, and analysed interdependencies among water quality parameters and microbiological characteristics of DWDS composed of different pipe materials. In addition, the fuzzy technique for order preference by similarity to ideal solution (FTOPSIS) ranked the most common bacteria identified during trials in a DWDS according to their relative abundance while managing vagueness…

A Multi-Criteria Group Decision To Support The Maintenance Service: A Case Study

2015

The present paper wants to propose a methodology to support a group of decision makers into the choice of actions, to implement on a multi-component system, regarding the maintenance service. The choice has to be made on the basis of several criteria, namely the total maintenance cost, the system unavailability and by considering the maintenance actions feasibility. In particular, with the aim to select the maintenance service that represents for the group the best comprise among the criteria to satisfy, the proposed methodology consists of two multi-criteria decisions methods to apply in two successive phases. The first one regards the application of the Analytic Hierarchy Process (AHP) to…

PROTEOMIC ANALYSIS OF AMYCOLATOPSIS BALHIMYCINA TO REVEAL NOVEL LINKS BETWEEN PRIMARY AND SECONDARY METABOLISM.

2007

Clean Agent Selection Approached by Fuzzy TOPSIS Decision-Making Method

2008

Abstract. It is well known that halons are ozone-depleting substances and their release into the atmosphere has contributed in the last decades to the reduction in the ozone layer. In consequence to the Montreal Protocol, an international agreement designed to gradually eliminate the use of such substances, fire protection industry researchers faced the challenge of finding effective solutions to replace halon extinguishers. This research aims to provide a method to support the decision maker in the selection of the most suitable extinguisher substance for a specific application. According to such framework, a set of quantitative and qualitative criteria has been established in the decision…