Search results for "TRANSFORMATION"
showing 10 items of 1634 documents
The Orchestra of Multiple Model Repositories
2013
This paper motivates and encourages the simultaneous use of multiple model repositories in model-driven software. A multi-repository mechanism is proposed for that. With this mechanism, multiple model repositories residing in the same or different technical spaces can be mounted into a single repository (in the same sense as file systems are mounted in UNIX) and accessed in a uniform way. Relations (including generalizations) between elements from the mounted repositories are supported. Some of the repositories may be “computable” (virtual), which leads to the on-the-fly model transformation concept.
Las grandes exposiciones del siglo XXI frente a la fragilidad del territorio
2019
Las exposiciones no son eventos autónomos ni homogéneos, al contrario, su desarrollo constituye la trama de una historia discontinua, el espejo de una sociedad en evolución que experimenta sus reglas y sus paradigmas, mostrándolos a la sociedad. A través de cartografía y bibliografía específica, además de las experiencias personales de los autores, se analizan los eventos de Hannover (2000) que marca el comienzo de las exposiciones del presente siglo, Shanghái (2010), y Milán (2015) para comprender los efectos que los eventos expositivos tienen sobre la transformación de la ciudad y del territorio, en un momento en el cual existe una renovada preocupación sobre el devenir de las ciudades, s…
enviPath - The environmental contaminant biotransformation pathway resource
2016
The University of Minnesota Biocatalysis/Biodegradation Database and Pathway Prediction System (UM-BBD/PPS) has been a unique resource covering microbial biotransformation pathways of primarily xenobiotic chemicals for over 15 years. This paper introduces the successor system, enviPath (The Environmental Contaminant Biotransformation Pathway Resource), which is a complete redesign and reimplementation of UM-BBD/PPS. enviPath uses the database from the UM-BBD/PPS as a basis, extends the use of this database, and allows users to include their own data to support multiple use cases. Relative reasoning is supported for the refinement of predictions and to allow its extensions in terms of previo…
Loss of virulence in Ustilago maydis by Umchs6 gene disruption
2003
A gene encoding a sixth chitin synthase (Umchs6, sequence GenBank accession No. AF030554) from the plant pathogenic hemibasidiomycete Ustilago maydis (DC.) Cda. was isolated and characterized. The predicted protein is 1103 amino acids in length with a calculated molecular mass of 123.5 kDa. a2b2 null mutants were obtained by substitution of a central fragment of the Umchs6 gene with the hygromycin resistance cassette, and a1b1 null mutants were obtained by genetic recombination in plants of an a2b2Δch6 and a wild-type a1b1 strain. The mutation had no effect on the dimorphic transition in vitro or on mating, and growth rate of the mutants was only slightly reduced. On the other hand, they di…
Human Papilloma Virus-Dependent HMGA1 Expression Is a Relevant Step in Cervical Carcinogenesis
2008
HMGA1 is a member of a small family of architectural transcription factors involved in the coordinate assembly of multiprotein complexes referred to as enhanceosomes. In addition to their role in cell proliferation, differentiation, and development, high-mobility group proteins of the A type (HMGA) family members behave as transforming protoncogenes either in vitro or in animal models. Recent reports indicated that HMGA1 might counteract p53 pathway and provided an interesting hint on the mechanisms determining HMGA's transforming potential. HMGA1 expression is deregulated in a very large array of human tumors, including cervical cancer, but very limited information is available on the mole…
Managing digital transformation: The view from the top
2022
Digital Transformation is upending businesses everywhere. While there is ample research on this topic, there is a clear gap when it comes to understanding the changing talent management role of senior executives in digital transformation processes and the demands of individual employees. This article relies on 23 in-depth interviews with senior managers who are leading all or some of the digital transformation efforts of their respective organizations. Our research, using a grounded theory approach, identifies four key activities (and 37 sub-activities or themes) stemming from the new managerial needs and talent management practices arising from DT processes. We branded these key activities…
Vampīrs un tā transformācija Annas Raisas romānā “Intervija ar vampīru” un tā ekranizācijā
2016
Vampīru tēma tiek plaši pētīta, un vampīra tēls ir kļuvis par nozīmīgu mūsdienu kultūras daļu. Šis maģistra darbs pēta vampīru Annas Raisas romānā un tā ekranizācijā, izmantojot tādus ar vampīrismu saistītus galvenos aspektus un elementus kā asinis, seksualitāte un eroticisms, nāve, identitāte un citādais, lai noteiktu, kādas vampīram raksturīgās iezīmes Raisa ir izmantojusi un kādas ir ieviesusi, tādējādi mainot priekšstatu par vampīru literatūrā un filmās. Iegūtie pētījuma rezultāti ļauj secināt, ka Raisas radītajam vampīram piemīt tādas agrīnajam vampīra tēlam raksturīgās pazīmes kā pievilcība, pārdabiskas spējas un nepieciešamība pēc asinīm, taču galvenā atšķirīgā iezīme ir tā cilvēcisk…
Bēgšana no realitātes Maikla Šabona darbā „Kavaliera un Kleja brīnumainie piedzīvojumi”
2017
Šajā darbā tiek pētīta terminu “bēgšana no realitātes” un “literatūra bēgšanai no realitātes” nozīme, un tiek parādīts, kā laika gaitā ir attīstījusies šo jēdzienu uztvere. Darba galvenā daļa ir veltīta tam, lai analizētu, vai Maikla Šabona darbs “Kavaliera un Kleja brīnumainie piedzīvojumi” var tikt kategorizēts kā literatūra bēgšanai no realitātes, izpētot dažādus bēgšanas no realitātes veidus, kas parādās šajā grāmatā, kā arī izpētot attiecības starp fantastikas literatūru un Holokausta literatūru. Darba galvenais secinājums ir tāds, ka bēgšana no realitātes ne vienmēr ir bezjēdzīga un “Kavaliera un Kleja brīnumainie piedzīvojumi” ir grāmata, kas parāda bēgšanas no realitātes transformēj…
New Business Models In-The-Making in Extant MNCs: Digital Transformation in a Telco
2017
In recent years, we can observe the emergence of firms, born both digital and global, that have disrupted existing industries. Deploying digital technologies, they have developed innovative value chains and business models that threaten established multinational companies (MNCs). In this chapter, we examine how MNCs can and do respond to the challenge digital technologies represent. We describe the main facets of digital technologies and discus the potential these have to undermine the value chains and business models of established MNCs. In order to illustrate this, we employ longitudinal data from Telenor, a leading multinational mobile telecom company. Telenor perceives digitalization as…
Relationships Between Personal Values and Leadership Behaviors in Basketball Coaches.
2018
Background: Based on the refined theory of basic individual values and transformational leadership theory, this study focuses on the associations between coaches' value priorities and their transformational leadership behaviors, exploring the potential mediation versus moderation effect of two alternative variables in this relationship: perceived club pressure or an autonomy supportive environment. Methods: Participants were 266 basketball coaches (85.7% men) from 17 to 66 years old (M = 32.82, SD = 9.2) from 119 different Spanish clubs. On average, they had worked for their current sport clubs for 5.02 years, and they had a mean of 11.10 years of experience. The coaches were all Spanish sp…