Search results for "TRANSFORMATION"

showing 10 items of 1634 documents

The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value

2021

AbstractIron is a fundamental nutrient utilized by living cells to support several key cellular processes. Despite its paramount role to sustain cell survival, excess of labile iron availability can inflict severe cell damage via reactive oxygen species generation which, in turn, can promote neoplastic transformation. The lung is particularly sensitive to iron-induced oxidative stress, given the high oxygen tensions herein present. Moreover, cigarette smoke as well as air pollution particulate can function as vehicles of iron supply, leading to an iron dysregulation condition shown to be crucial in the pathogenesis of several respiratory diseases including lung cancer. Hephaestin (HEPH) bel…

hephaestinCancer ResearchHephaestinSettore MED/08 - Anatomia Patologicamedicine.disease_causeironmedicineSettore MED/05 - Patologia ClinicaNeoplastic transformationLung cancerCell damageRC254-282Original ResearchTumor microenvironmentbiologybioinformaticCancerNeoplasms. Tumors. Oncology. Including cancer and carcinogensbioinformaticsmedicine.diseaseGene expression profilingbioinformatics; hephaestin; immunohistochemistry; iron; lung cancerlung cancerOncologyimmunohistochemistrybiology.proteinCancer researchAdenocarcinomaCeruloplasminCarcinogenesisOxidative stressFrontiers in Oncology
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Examples of UV–Vis profiles use as tool for evidence of the metallophthalocyanines transformation

2017

Abstract The UV–Vis spectra for a set of MPcs (Mmetal, Pc = phthalocyanine ligand), i.e.: In(III)PcI (1), Hf(IV)PcI2Pht (Pht = phthalonitrile) (2), Sn(II)Pc (3), Sn(IV)PcI2 (4), and Ge(IV)PcI2 (5) have been examined in two solvents, O-donative acetylacetone, and non-coordinative benzene. The UV–Vis spectra in Hacac solution of 1,2 and 4,5 shows that the axially ligated iodine atoms are replaced by (acac)− anions of the solvent, whereas in 3 the oxygen donors of the solvent causing the auto-oxidation of Sn(II) to Sn(IV) ions and as a result the Sn(II)Pc is transformed into the Sn(IV)Pc(acac)2. The chloride complexes of the 1–5 compounds are formed at Hacac solution after acidification by hyd…

hydrochloric acidAcetylacetoneInorganic chemistryHydrochloric acid010402 general chemistrydemetalation01 natural sciencesChlorideAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundUltraviolet visible spectroscopymedicineBenzeneSpectroscopyautooxidationAutoxidation010405 organic chemistryLigandtransformationOrganic Chemistry0104 chemical sciencesSolventchemistryPhysical chemistrymetallophthalocyaninesspectrum UV–Vismedicine.drugJournal of Molecular Structure
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Reflections on the human role in AI policy formulations : how do national AI strategies view people?

2022

Abstract Purpose There is no artificial intelligence (AI) without people. People design and develop AI; they modify and use it and they have to reorganize the ways they have carried out tasks in their work and everyday life. National strategies are documents made to describe how different nations foster AI and as human dimensions are such an important aspect of AI, this study sought to investigate major national strategy documents to determine how they view the human role in emerging AI societies. Approach Our method for analyzing the strategies was conceptual analysis since the development of technology is embedded with conceptual ideas of humanity, explicit or implicit, and in addition to…

ihmisen ja tietokoneen vuorovaikutushuman-technology interaction (HTI)social transformationteknologinen kehitysethical AItekoälyartificial intelligenceeettisyysinnovaatiothuman-computer interaction (HCI)strategiatAI strategiesihminen-konejärjestelmätyhteiskunnallinen muutostulevaisuusinhimillisyyshuman factorsAI policyinhimilliset tekijät
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Added Value of Intangibles for Organizational Innovation

2012

The purpose of this paper is to present the theoretical basis for a measurement and improvement system that will help organizations create a more innovative climate. The role of intangible assets in contributing to organizational innovativeness is clarified within six hypotheses on the basis of a cross-disciplinary literature review combining studies from psychology, human resources management, communication, information technology, and marketing. These factors range from the individual level to interaction with the environment surrounding the organization, and involve (a) individual psychological flexibility, (b) institutional and interpersonal trust, (c) diverse human resources, (d) strat…

intangiblesflexibilityorganizational trusttransformational leadershipinnovation
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Playing with Format (1)

2021

International audience; Le volume 45 de la revue Interfaces propose une réflexion sur la double nature du format, comme contrainte et condition de la créativité. Il aborde le rôle du format dans la création, développant une réflexion sur ses usages en art, en poésie, dans le théâtre, dans le domaine du livre, des périodiques et de productions telles que les carnets d’artistes. Il met en exergue la dimension expérimentale des variations de format dans les processus de création artistique et les stratégies éditoriales ou de conservation, ainsi que les pratiques hybrides (texte / image) et les transferts intermédiaux.

intermedialityreceptionintermédialité[SHS.LITT] Humanities and Social Sciences/Literatureépistémologie[SHS.LITT]Humanities and Social Sciences/LiteratureréceptiontransformationBook historyformatHistoire du livre[SHS.ART] Humanities and Social Sciences/Art and art history[SHS.ART]Humanities and Social Sciences/Art and art history
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Staging American Nights : Représentations de l’intime et mises en scène de la nuit aux Amériques

2020

Aux rêveurs noctambules de tout temps, aux « dériveurs » nocturnes, la nuit est réservoir de symboles, éveil d’un monde intérieur, souvenirs et obsessions intimes, révélation de l’inconscient, autre jubilation dionysiaque. Rêve d’encre aussi, veille des créateurs dans la nuit théophanique quand mystique de la nature et mystique intime s’y lovent : c’est la nuit obscure de St-Jean de la Croix, ténèbres de l’âme abandonnée, et la Sainte pénombre des pré-romantiques et romantiques allemands (Goë...

intermédialiténight[SHS.LITT]Humanities and Social Sciences/Literaturelcsh:HM401-1281adaptationintimacy[SHS.LITT] Humanities and Social Sciences/Literature[SHS.PHIL] Humanities and Social Sciences/PhilosophyComputingMilieux_MISCELLANEOUS[SHS.MUSIQ]Humanities and Social Sciences/Musicology and performing artstransformationGeneral Engineering[SHS.PHIL]Humanities and Social Sciences/Philosophystagingspace[SHS.ART]Humanities and Social Sciences/Art and art historymise en scène[SHS.MUSIQ] Humanities and Social Sciences/Musicology and performing artsimageslcsh:Sociology (General)espaceintimesilence[SHS.ART] Humanities and Social Sciences/Art and art historyAmériquesAmericasnuit
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The transformation of the Horatian Sabine farm in Persius? Satire 6

2020

The purpose of this article is to focus on the motif of the countryside in Roman satire. In particular, it aspires to study the way the Sabine farm is delineated in Horace's Satire 2.6 and later in his Epistles, in order to elucidate the evolution of this motif in Persius? 6th Satire. In this poem, Persius addresses Caesius Bassus, who retreats to Sabine to seek poetic inspiration, but seems trapped in the paths of earlier poetry and cannot attain bliss, while the poet achieves it in the port of Luna.

it aspires to study the way the Sabine farm is delineated in Horace's Satire 2.6 and later in his EpistlesUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASPersius addresses Caesius Bassusbut seems trapped in the paths of earlier poetry and cannot attain bliss:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]in order to elucidate the evolution of this motif in Persius? 6th Satire. In this poemwho retreats to Sabine to seek poetic inspirationwhile the poet achieves it in the port of Luna. 33 451135-9560 8276 Studia philologica valentina 567083 2020 22 7762312 The transformation of the Horatian Sabine farm in Persius? Satire 6 KallergiAnthofili The purpose of this article is to focus on the motif of the countryside in Roman satire. In particular
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Towards Sustaining Levels of Reflective Learning: How Do Transformational Leadership, Task Interdependence, and Self-Efficacy Shape Teacher Learning …

2015

Whereas cross-sectional research has shown that transformational leadership, task interdependence, and self-efficacy are positively related to teachers’ engagement in reflective learning activities, the causal direction of these relations needs further inquiry. At the same time, individual teacher learning might play a mutual role in strengthening school-level capacity for sustained improvement. Building on previous research, this longitudinal study therefore examines how transformational leadership, task interdependence, self-efficacy, and teachers’ engagement in self-reflection mutually affect each other over time. Questionnaire data gathered on three measurement occasions from 655 Dutch …

jel:Z1Longitudinal studymedia_common.quotation_subjectReflective practiceeducationjel:P0task interdependencejel:P1jel:P2Affect (psychology)jel:P3jel:P4jel:P5Task (project management)jel:P0502 economics and businesstransformational leadershiptransformational leadership; task interdependence; self-efficacy; self-reflection; latent difference score model; vocational education and traininglcsh:Social sciences (General)media_commonLatent difference score model; vocational education and trainingSelf-efficacyTeamworkvocational education and training4. Education05 social sciencesjel:A14050301 educationGeneral Social Sciencesjel:A13self-reflectionlatent difference score modelTransformational leadershipVocational educationlcsh:H1-99Psychology0503 educationSocial psychologyself-efficacy050203 business & managementSocieties
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Johtaminen on dialogia ja liikettä päiväkodin johtajien kokemuksia julkisen varhaiskasvatuksen organisaatiomuutoksista ja muutosjohtamisesta

2009

johtaminenvarhaiskasvatuspäiväkoditorganisaatiotransformational leadershipmuutosjohtaminen
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The transformation of R&D into neo open innovation- a new concept in R&D endeavor triggered by amazon

2019

Amazon was the world's top Research and Development (R&D) firm in 2017. Its R&D investment was double that of 2015, five times that of 2012, and ten times that of 2011. Such a rapid and notable increase in R&D investment has raised the question of a new R&D definition and focus in the digital economy, which Amazon insists includes both “routine or periodic alterations” (traditionally classified as non-R&D) and “significant improvement” (classified as R&D). Using an empirical analysis of Amazon's R&D model as a system, this paper attempts to provide a convincing answer to this question. It has been identified that Amazon, which is based on R&D as a culture, has been promoting companywide exp…

kansainväliset yrityksetSociology and Political Science020209 energymedia_common.quotation_subjectHuman Factors and Ergonomics02 engineering and technologyEducationresearch and developmentinnovaatiotoimintatutkimus- ja kehittämistoiminta0502 economics and business0202 electrical engineering electronic engineering information engineeringEconomicsDigital economyBusiness and International ManagementArchitectureuser-driven innovationFunction (engineering)AmazonIndustrial organizationneo open innovationOpen innovationmedia_commonbusiness.industryAmazon rainforesttransformation05 social sciencesuusi talousInvestment (macroeconomics)Virtuous circle and vicious circleinnovaatiotThe Internetbusiness050203 business & management
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