Search results for "TRES"
showing 10 items of 6927 documents
Hot water injection in relation to 1982-84 microseismic events at Campi Flegrei Caldera by thermo-hydro-mechanical simulation
2020
The repeated deformations and seismic unrests at Campi Flegrei caldera (southern Italy) have been identified due to a fluid injection source in volcano active area. We investigated the role of hot water injection in the seismic unrests of 1982-1984 with a view to gaining insights into the caldera’s dynamics, by applying coupled TOUGHREACT-FLAC3D simulator to our computational domain of 10 × 1 × 3 km with a single-phase steam isothermal (HM) and non-isothermal (THM) simulations comparison. The results indicated that the overlying caprock blocks the uprising hot water injection, leading to the building up of pore pressure and shear stress underneath over time. This process substantially modif…
Alzheimer's disease: new diagnostic and therapeutic tools.
2008
Abstract On March 19, 2008 a Symposium on Pathophysiology of Ageing and Age-Related diseases was held in Palermo, Italy. Here, the lectures of M. Racchi on History and future perspectives of Alzheimer Biomarkers and of G. Scapagnini on Cellular Stress Response and Brain Ageing are summarized. Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disease, which in Western society mainly accounts for clinica dementia. AD prevention is an important goal of ongoing research. Two objectives must be accomplished to make prevention feasible: i) individuals at high risk of AD need to be identified before the earliest symptoms become evident, by which time extensive neurodege…
Systemic inflammatory response in erderly patients following hernioplastical operation
2006
Abstract The number of old and oldest old patients undergoing surgery of varying severity is increasing. Ageing is a process that changes the performances of most physiological systems and increases susceptibility to diseases and death; accordingly, host responses to surgical stress are altered with ageing and the occurrence of age-related increase in susceptibility to post-operative complications has been claimed. Twenty-four male patients undergoing Lichtenstein (LH) hernioplasty for unilateral inguinal hernia were included in this study and divided in two groups (Young and Old respectively), according to their age. As expression of the acute phase response, we measured changes in concent…
Jocs de llenguatge en escena
2015
Resum: Aquest article gira a l’entorn de la presència, en l’escena catalana, del contrast de registres lingüístics en unes versions que van més enllà del marc estricte de la normativa oficial. A aquest efecte, s’utilitzen com a objectes d’anàlisi les versions de dues peces teatrals dutes a terme en contextos històrics i sociopolítics molt diferents —la de Joan Oliver de Pygmalion, de G.B. Shaw (1957), i la de Joan Sellent de Translations, de Brian Friel (2014)— i se’n ressalten les afinitats i diferències, tant pel que fa a la tria dels materials lingüístics com als objectius dramatúrgics i ideològics.Tant en una versió com en l’altra, la transgressió freqüent de les normes de la Secció Fil…
Is it me or the music? : Stress reduction and the role of regulation strategies and music
2019
Music is a common resource for the regulation of emotions, moods, and stress. This study aimed at determining the individual and relative impact on stress reduction of two of the main factors involved in musical affect regulation: regulation strategies and music itself. The current study took place in an experimental setting and followed a factorial within-subjects design. First, the participants ( n = 34) filled in an online survey where they identified their self-perceived “adequate”/“inadequate” music examples for the purpose of reducing stress and self-perceived “adequate”/“inadequate” strategies for the same purpose. In the lab they went through a stress induction procedure and then w…
The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2.
2015
The NG2 proteoglycan is characteristically expressed by oligodendrocyte progenitor cells (OPC) and also by aggressive brain tumours highly resistant to chemo- and radiation therapy. Oligodendrocyte-lineage cells are particularly sensitive to stress resulting in cell death in white matter after hypoxic or ischemic insults of premature infants and destruction of OPC in some types of Multiple Sclerosis lesions. Here we show that the NG2 proteoglycan binds OMI/HtrA2, a mitochondrial serine protease which is released from damaged mitochondria into the cytosol in response to stress. In the cytosol, OMI/HtrA2 initiates apoptosis by proteolytic degradation of anti-apoptotic factors. OPC in which NG…
Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues
2019
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia and insulin resistance in which oxidative stress is thought to be a primary cause. Considering that mitochondria are the main source of ROS, we have set out to provide a general overview on how oxidative stress is generated and related to T2D. Enhanced generation of reactive oxygen species (ROS) and oxidative stress occurs in mitochondria as a consequence of an overload of glucose and oxidative phosphorylation. Endoplasmic reticulum (ER) stress plays an important role in oxidative stress, as it is also a source of ROS. The tight interconnection between both organelles through mitochondrial-associated membranes (MAM…
La intervención cognitivo-conductual mejora la cognición de los cuidadores de personas con trastorno del espectro autista: estudio piloto
2017
Abstract As postulated by the stress process model, chronically stressed individuals, such as caregivers of people with chronic psychological disorders, have poorer cognitive performance and higher age-related cognitive decline than individuals not exposed to chronic stress. When analysing this topic in caregivers, the majority of research has been conducted in populations in which the care recipient has dementia and/or Alzheimer's disease, while relatively few studies have analysed cognition in caregivers of offspring with autism spectrum disorder (ASD). The main objective of this pilot study was to analyse the effect of a cognitive-behavioural intervention on cognition in caregivers of pe…
CANCER SURVIVORSHIP: THE NEED FOR COMPREHENSIVE CARE AND THE IMPORTANCE OF ASSUMING AN ACTIVE ROLE
2019
Advances in the early detection and treatment of cancer have led to an increase in the number of people who have overcome the disease, reaching 5% of the current population in our country. As indicated by the Sociedad Española de Oncología Médica [Spanish Society of Medical Oncology], this situation involves new challenges that require, among other things, the identification of and attention to the quality of life and the psychosocial needs of this growing population. The objective of this article is to reflect on the importance of comprehensive, specialized, and multidisciplinary care, in which the survivor has a more active participation. However, previously, the debate on the concept of …
Volitional components of consciousness vary across wakefulness, dreaming and lucid dreaming
2014
Contains fulltext : 136156.pdf (Publisher’s version ) (Open Access) Consciousness is a multifaceted concept; its different aspects vary across species, vigilance states, or health conditions. While basal aspects of consciousness like perceptions and emotions are present in many states and species, higher-order aspects like reflective or volitional capabilities seem to be most pronounced in awake humans. Here we assess the experience of volition across different states of consciousness: 10 frequent lucid dreamers rated different aspects of volition according to the Volitional Components Questionnaire for phases of normal dreaming, lucid dreaming, and wakefulness. Overall, experienced volitio…