Search results for "TRES"

Screw‐in‐screw fixation of fragility sacrum fractures provides high stability without loosening—biomechanical evaluation of a new concept

2020

Surgical treatment of fragility sacrum fractures with percutaneous sacroiliac (SI) screw fixation is associated with high failure rates. Turn-out is detected in up to 20% of the patients. The aim of this study was to evaluate a new screw-in-screw implant prototype for fragility sacrum fracture fixation. Twenty-seven artificial hemipelvises were assigned to three groups (n = 9) for instrumentation of an SI screw, the new screw-in-screw implant prototype, ora transsacral screw. Before implantation, a vertical osteotomy was set in zone 1 after Denis. All specimens were biomechanically tested to failure in upright position. Validated setup and test protocol were used for complex axial and torsi…

An update on the relationships between rheumatoid arthritis and atherosclerosis

2010

Rheumatoid arthritis is a chronic inflammatory disease. Cardiovascular events are the most important cause of mortality and morbidity in patients with rheumatoid arthritis. Beyond the traditional cardiovascular risk factors, chronic systemic inflammation has been shown to be a crucial factor in atherosclerosis development and progression from endothelial dysfunction to plaque rupture and thrombosis. Many studies have shown that atherosclerosis is not a passive event like accumulation of lipids in the vessel walls; by contrast, it represents an active inflammation of the vessels. Inflammatory cells such as macrophages, monocytes and T cells play important roles in the development of both rhe…

Enhanced prolylhydroxylase activity in the posterior annulus fibrosus of canine intervertebral discs following long-term running exercise

2010

The effect of long-term excercise on the intervertebral disc collagen concentration (hydroxyproline), collagen-synthesizing enzymes (prolyl-4-hydroxylase, PH, and galactosyl-hydroxylysyl glucosyltransferase, GGT) and hydroxypyridinium crosslinks was studied in ten female beagle dogs. The dogs were run on a treadmill for 1 year starting at the age of 15 weeks. The daily running distance was gradually increased to 40km, which distance the dogs ran for the final 15 weeks. Ten untrained dogs from the same breeding colony served as controls. The nucleus pulposus and anterior and posterior halves of the annulus fibrosus of C2-3, T10-12, L4-5 disc segments were analysed. Crosslinks were measured f…

A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA b…

2002

The Cockayne syndrome B (CSB) gene product is involved in the repair of various types of base modifications in actively transcribed DNA sequences. To investigate its significance for the repair of endogenous oxidative DNA damage, homozygous csb(-/-)/ogg1(-/-) double knockout mice were generated. These combine the deficiency of CSB with that of OGG1, a gene coding for the mammalian repair glycosylase that initiates the base excision repair of 7,8-dihydro-8-oxoguanine (8-oxoG). Compared to ogg1(-/-) mice, csb(-/-)/ogg1(-/-) mice were found to accumulate with age severalfold higher levels of oxidited purine modifications in hepatocytes, splenocytes and kidney cells. In contrast, the basal (ste…

Patient-specific computational evaluation of stiffness distribution in ascending thoracic aortic aneurysm

2021

Quantifying local aortic stiffness properties in vivo is acknowledged as essential to assess the severity of an ascending thoracic aortic aneurysm (ATAA). Recently, the LESI (local extensional stiffness identification) methodology has been established to quantify non-invasively local stiffness properties of ATAAs using electrocardiographic-gated computed tomography (ECG-gated CT) scans. The aim of the current study was to determine the most sensitive markers of local ATAA stiffness estimation with the hypothesis that direct measures of local ATAA stiffness could better detect the high-risk patients. A cohort of 30 patients (12 BAV and 18 TAV) referred for aortic size evaluation by ECG-gated…

Musiikin kuuntelu itsehoidollisena menetelmänä stressin lievityksessä

2016

Tämän tutkielman tarkoituksena oli tarkastella musiikin kuuntelua stressin lievityksessä arkipäivässä. Musiikin kuuntelun on todettu lievittävän stressiä tehokkaasti mutta aiemmat tutkimukset aiheesta ovat olleet lähinnä määrällisiä. Tässä tutkimuksessa aihetta lähestyttiin laadullisin menetelmin, jossa pyrittiin stressin lievityksen osalta kartoittamaan musiikillisten piirteiden lisäksi myös ihmisten kokemuksia aiheesta. Tutkimus toteutettiin haastattelemalla neljää henkilöä, jotka kuuntelivat musiikkia arkipäivässään stressin lievitykseen. Haastatteluaineisto analysoitiin sisällönanalyysin keinoin. Tutkimustulosten myötä havaittiin, että stressin lievityksessä musiikin tärkeimmät piirteet…

Women's Emotions Towards the Mobile Phone

2012

The purpose of this study is to investigate whether women's emotions associate differently with the mobile phone depending on the type of family in which they live. James A. Russell's circumplex model of affect which explores four main emotional dimensions, excitement, distress, depression and contentment, was applied. The article is based on the female sub-sample (N = 3,704) of nationally representative survey data collected from Italy, France, the UK, Germany and Spain (N = 7,255) in 2009. The results show that it is women living in blended families who seem to associate more distress and less feelings of contentment with the mobile phone than women living in other types of family. peerRe…

Naisliikunnanopettajien kokemuksia työssä jaksamisesta

2002

Perfekcionisma saistība ar prokrastināciju un stresa pārvarēšanas stratēģijām

2015

Maģistra darba mērķis bija noskaidrot, vai adaptīvam perfekcionismam, salīdzinot ar neadaptīvo perfekcionismu, būs raksturīgs zemāks prokrastinācijas līmenis un augstāki rādītāji adaptīvajās stresa pārvarēšanas stratēģijās. Pētījumā piedalījās 116 respondentu, no kuriem 45 ir vīrieši un 71 - sievietes. Vecumā no 18 līdz 35 gadiem. Darbā tika izmantotas: perfekcionisma aptauja (APS-R SF; Almost Perfect Scales Revised Short Form) (Slaney, Rice, Mobley, Trippi, & Ashby, 2001), stresa pārvārēšanas stratēģiju aptauja (The COPE Inventory) (Carver, Scheier, & Weintraub, 1989) un prokrastinācijas aptauja (Procrastinatination Scale) (Lay, 1986). Pētījuma galvenie secinājumi ir, ka adaptīvajiem perfe…

A basic need theory approach to problematic Internet use and the mediating effect of psychological distress

2015

The Internet provides an easily accessible way to meet certain needs. Over-reliance on it leads to problematic use, which studies show can be predicted by psychological distress. Self-determination theory proposes that we all have the basic need for autonomy, competency, and relatedness. This has been shown to explain the motivations behind problematic Internet use. This study hypothesizes that individuals who are psychologically disturbed because their basic needs are not being met are more vulnerable to becoming reliant on the Internet when they seek such needs satisfaction from online activities, and tests a model in which basic needs predict problematic Internet use, fully mediated by p…