Search results for "TRES"

showing 10 items of 6927 documents

Antioxidant Therapies and Oxidative Stress in Friedreich´s Ataxia: The Right Path or Just a Diversion?

2020

Friedreich's ataxia is the commonest autosomal recessive ataxia among population of European descent. Despite the huge advances performed in the last decades, a cure still remains elusive. One of the most studied hallmarks of the disease is the increased production of oxidative stress markers in patients and models. This feature has been the motivation to develop treatments that aim to counteract such boost of free radicals and to enhance the production of antioxidant defenses. In this work, we present and critically review those 'antioxidant' drugs that went beyond the disease's models and were approved for its application in clinical trials. The evaluation of these trials highlights some …

reactive oxygen speciesFriedreich’s ataxia; clinical trials; oxidative stress; antioxidant therapies; reactive oxygenspecies; scavengers; antioxidant response; mitochondrial metabolism; ferroptosisclinical trialsmitochondrial metabolismantioxidant responseEstrès oxidatiulcsh:RM1-950Friedreich’s ataxiaReviewFriedreich´s ataxia590 Tiere (Zoologie)Antioxidantsferroptosisscavengerslcsh:Therapeutics. Pharmacology570 Biowissenschaften Biologieddc:590oxidative stressantioxidant therapiesddc:570Antioxidants
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The Role of Work-Nonwork Boundary Management in Work Stress Recovery

2016

The aim of the present study conducted among 1,106 Finnish employees was to identify boundary management profiles based on cross-role interruption behaviors from work to nonwork and from nonwork to work. Adopting a person-oriented approach through latent profile analysis, 5 profiles were identified: Work Guardians (21% of the employees), Nonwork Guardians (14%), Integrators (25%), Separators (18%), and an Intermediate Group (22%). We then examined differences between these profiles with respect to recovery experiences (psychological detachment from work, relaxation, mastery experiences, and control during off-job time) and recovery outcomes (vigor and exhaustion). Work Guardians had the poo…

recovery experiencesstressiwork stresstyöstressiwork-nonwork boundariesuupumus
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Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women.

2017

It is known amateur female athletes show an altered redox status [1] and the consumption of Opuntia Ficus Indica (OFI) decreases oxidative stress (OS) in healthy humans [2]. Therefore, the aim of this study was to investigate whether the supplementation with Sicilian OFI juice affected plasma redox balance following a maximal effort test in young physically active women
 . This study was randomized, double blind, placebo controlled and crossover design. Eight women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm and BMI of 21.69±0.66 kg/m2) were randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml …

redox balanceSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' Sportiveoxidative stressindicaxanthinSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieAntioxidant supplementationAntioxidant supplementation; oxidative stress; redox balance; indicaxanthin
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Moderate overexpression of glucose-6-phosphate dehydrogenase improves healthspan in mice. Implications in skeletal muscle regeneration

2019

An enormous increment in the average lifespan of diverse populations occurred worldwide in the 20th century. In the last 10–15 years, the importance has changed from extending average and even maximal longevity to favoring healthy aging, and many researchers have focused their studies on the aim at extending healthspan. Prolonging lifespan without taking care of improving healthspan can derive in a long time of living with disabilities and constitutes a risk factor for the old population to suffer a higher prevalence of aging-related diseases. Indeed, modern disease treatments frequently diminish mortality without any effect on the deterioration of overall health. Understanding the mechanis…

regenerationagingUNESCO::CIENCIAS MÉDICASoxidative stresshealthspanskeletal muscle:CIENCIAS MÉDICAS [UNESCO]g6pd
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People buried in St Leger's chapel to Alise-Sainte-Reine ( Burgundy, France): reflections on the discrepancy between the archaeological data and the …

2003

As burial registers corresponding to a fully excavated funeral assemblage are rather rare, the present study endeavours toexamine both wrritten data and bone remains from a chape frequented during the 17th and 18th centuries. The disparity between thepopulatiom described by the two types of sources, particularly concerning the proportions of children in each, would encourage us toreconsider wiith caution the evaluation of burial groups based on bone assemblages which are not informed by written sources. Analysisof the latter will allow us to evaluate more accurately just how representative the archaeological evidence is with respect to the overalloccupation of a given site.

registres de décèsparish burial registerarchéologie funéraireÉpoque moderne[SHS.HIST] Humanities and Social Sciences/HistoryXVIII centuryArchaeological anthropologyanthropologie historique[SHS] Humanities and Social Sciences[SHS.HIST]Humanities and Social Sciences/Historyméthodologie[SHS]Humanities and Social Sciences
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Affect self-regulation through music

2018

The present dissertation focused on musical affect regulation, i.e. on the use of music to self-regulate affective states such as emotions, moods, and energy levels. In publication I, relevant findings from previous research were extracted and the field’s conceptual clarity and precision was assessed. Besides identifying weaknesses in conceptualization and providing recommendations for future studies, publication I found that not all the elements of affect regulation through music have been equally explored by research. Given the gap observed on the study of musical mechanisms underlying affect regulation, publication II placed a special focus on this component and its association with regu…

regulation strategiesmusiikkieveryday listeningmusical mechanismsstressiitsesäätelybehavioral disciplines and activitieshumanitiesstress responseskuunteleminennuorettunteetnuoruusmusicmekanismitaffect regulationhuman activities
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Validation of a Shear Model for RC and Hybrid Beams with Two Different Inclinations of Transversal Reinforcement

2016

The validation of an analytical model recently proposed for evaluation of the shear capacity in Reinforced Concrete (RC) beams containing multiple inclination of transverse stirrups is presented. The model is a suitable extension of that currently proposed in Eurocode 2 for the evaluation of the shear resistance, and it is derived by means of the the variable-inclination stressfield theory based on Nielsen’s plastic approach. Experimental and numerical data available in the literature on Hybrid Steel-Trussed Concrete Beams (HSTCBs) are used for model validation and result discussion. Finally, also the comparison with a different analytical approach for the assessment of the shear resistance…

reinforced concrete beamSettore ICAR/09 - Tecnica Delle Costruzionistress field approachprecast steel-concrete trussed beamstress field approach.analytical model; different inclined stirrups; precast steel-concrete trussed beams; reinforced concrete beams; shear strength; stress field approach.analytical modelshear strengthdifferent inclined stirrupdifferent inclined stirrupsprecast steel-concrete trussed beamsreinforced concrete beams
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A Path Model for Subjective Well-Being during the Second Wave of the COVID-19 Pandemic: A Comparative Study among Polish and Ukrainian University Stu…

2022

Background: Previous studies showed several associations between physical and mental health dimensions and well-being. This study aims to examine a complex path model explaining the life satisfaction of university students from Poland and Ukraine during the second wave of the COVID-19 pandemic. Methods: The cross-sectional web-based study was performed in November 2020 using Google Forms. The conventional sample of 3230 university students from Poland (n = 1581) and Ukraine (n = 1649), aged 18–59 (M = 21.40, SD = 3.46), with 59% women, participated in the study. We used standardized questionnaires to measure life satisfaction (SWLS), self-reported physical health (GSRH), perceived stress (P…

relationship statuswell-beingperceived stressanxiety; coronavirus-related PTSD; depression; gender; mental health; perceived stress; physical health; relationship status; university students; well-beingdepressiongenderGeneral Medicineuniversity studentsanxietycoronavirus-related PTSDphysical healthmental healthJournal of clinical medicine
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Bifactor analysis and construct validity of the five facet mindfulness questionnaire (FFMQ) in non-clinical Spanish samples

2015

The objective of the present study was to examine the dimensionality, reliability, and construct validity of the Five Facet Mindfulness Questionnaire (FFMQ) in three Spanish samples using structural equation modeling (SEM). Pooling the FFMQ data from 3 Spanish samples (n = 1191), we estimated the fit of two competing models (correlated five-factor vs. bifactor) via confirmatory factor analysis. The factorial invariance of the best fitting model across meditative practice was also addressed. The pattern of relationships between the FFMQ latent dimensions and anxiety, depression, and distress was analyzed using SEM. FFMQ reliability was examined by computing the omega and omega hierarchical c…

reliability and validityMindfulnessmindfulnesslcsh:BF1-990Bifactor modelFive Facet Mindfulness QuestionnaireLatent variablestructural equation modellingAnxietystructural equation modelingStructural equation modelingStructural equation modelingmedicinePsychologyGeneral PsychologyOriginal ResearchBifactor ModelDepressionCorrectionConstruct validityanxietystructural equation modeling (SEM)Confirmatory factor analysisDistressanxiety bifactor model depression five facet mindfulness questionnaire structural equation modelinglcsh:PsychologyFive facet mindfulness questionnairedepressionAnxietyPersonalitatmedicine.symptomfive facet mindfulness questionnairePsychologyFactor Analysis StatisticalSocial psychologyClinical psychology
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Finances II: Renda Fixa.

2016

El material explica com valorar tant els actius de renda fixa a curt plaç (lletres del Tresor i pagarés d'empresa, així com els actius de renda fixa a mig i llarg plaç (bons i obligacions).

renda fixaobligacionsUNESCO::CIENCIAS ECONÓMICASbonslletres del tresor
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