Search results for "TRIX"

Navi o pesci? Una nota a Seneca, Phaedra 472

2014

In f. 472 of Seneca's Phaedra (uacuum sine ullis classibus stabit mare) a brilliant conjecture of Richard Bentley, who proposed to read piscibus in place of classibus, has been adopted by the majority of later editions. By an analysis of both the discourses of the nurse and of Hippolytus, the paper attempts to prove the authenticity of the manuscript tradition

Collagen changes in the extracellular matrix of tumor-affected human breast: a tale of OF/LB and type V collagens

2010

It is widely acknowledged that the extracellular matrix (ECM) ofconnective tissues plays active roles in numerous biological processessuch as cell differentiation, life/death promotion and carcinogenesis.Ductal infiltrating carcinoma (DIC) of the breast is a highly metastatictumor histotype commonly associated with drastic massive alterations ofECM architecture and composition, especially concerning its collagenouscomponent. In particular, it was demonstrated that the stroma of DIC ofthe human breast contains a considerable amount of an embryo-foetalcollagen type (OF/LB), while type V collagen, which is a minorcomponent of normal human breast ECM, undergoes over-deposition inthe affected gl…

Close of a fistula between the nose and the oral cavity using a new collagen matrix

2016

Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinoma

2021

Aim: Type VI collagen, is emerging as a signaling collagen originating from different types of fibroblasts. A specific fragment of Type VI collagen, the pro-peptide, is also known as the hormone endotrophin. We hypothesized that this fibroblast hormone would be of particular relevance in cancer types with a high amount of fibrosis activity, namely for outcome in hepatocellular carcinoma (HCC) cirrhotic patients. Patients & methods: Plasma C6M, PRO-C6 and alphafeto-protein (AFP) were assessed in 309 patients with mixed etiologies (hepatitis C, hepatitis B, alcohol and nonalcoholic fatty liver) diagnosed as cirrhotics, cirrhotics with HCC, noncirrhotics and healthy controls. Progression-f…

Extracellular matrix fiber microarchitecture is region-specific in bicuspid aortic valve-associated ascending aortopathy

2016

Abstract Objective Ascending thoracic aortic aneurysm (ATAA) in patients with bicuspid aortic valve (BAV) commonly dilate asymmetrically compared with patients with tricuspid aortic valve (TAV). This discrepancy in aneurysm geometry led us to hypothesize that microarchitectural differences underlie the observed asymmetric dilatation pattern. The purpose of this study was to characterize the microarchitectural distinctions of the extracellular matrix of the 2 phenotypes with a focus on the proportion of radially oriented elastin and collagen fibers in different circumferential aortic regions. Methods Aortic tissue rings were obtained just distal to the sinotubular junction from patients with…

Zebrafish Fins as a Model System for Skeletal Human Studies

2007

Recent studies on the morphogenesis of the fins ofDanio rerio(zebrafish) during development and regeneration suggest that a number of inductive signals involved in the process are similar to some of those that affect bone and cartilage differentiation in mammals and humans. Akimenko et al. (2002) has shown that bone morphogenetic protein-2b (BMP2b) is involved in the induction of dermal bone differentiation during fin regeneration. Many other groups have also shown that molecules from the transforming growth factor-beta superfamily (TGFβ), including BMP2, are effective in promoting chondrogenesis and osteogenesisin vivoin higher vertebrates, including humans. In the present study, we review…

Sp1 transcription factor interaction with accumulated prelamin a impairs adipose lineage differentiation in human mesenchymal stem cells: essential r…

2012

Abstract Lamin A (LMNA)-linked lipodystrophies may be either genetic (associated with LMNA mutations) or acquired (associated with the use of human immunodeficiency virus protease inhibitors [PIs]), and in both cases they share clinical features such as anomalous distribution of body fat or generalized loss of adipose tissue, metabolic alterations, and early cardiovascular complications. Both LMNA-linked lipodystrophies are characterized by the accumulation of the lamin A precursor prelamin A. The pathological mechanism by which prelamin A accumulation induces the lipodystrophy associated phenotypes remains unclear. Since the affected tissues in these disorders are of mesenchymal origin, we…

Predictive control of convex polyhedron LPV systems with Markov jumping parameters

2012

The problem of receding horizon predictive control of stochastic linear parameter varying systems is discussed. First, constant coefficient matrices are obtained at each vertex in the interior of linear parameter varying system, and then, by considering semi-definite programming constraints, weight coefficients between each vertex are calculated, and the equal coefficients matrices for the time variable system are obtained. Second, in the given receding horizon, for each mode sequence of the stochastic convex polyhedron linear parameter varying systems, the optimal control input sequences are designed in order to make the states into a terminal invariant set. Outside of the receding horizon…

Exploratory remarks and discussion on a potential program for interlock even more the mathematics and physics

2021

These remarks are endowed with exploratory argumentation for disrupt further discussion and in favor of the in-depth consolidation of a mathematical and physics identification based on 2 key concepts: 1) finite support and 2) a notion of infinite intrinsic to the usage of the complex numbers. General relativity shows up linked to a kind of a Gelfand representation as an approximation of an analog of a hidden Markov Model. This has deep connections with the Stone–Weierstrass theorem and these discussion are an invitation to the physics community to study the physics x mathematics identification in the case of a holding true multiverse hypothesis. Photon in this setup stands to the analog of …

Active-passive decentralized H∞ control for adjacent buildings under seismic excitation

2011

Author's version of a chapter in the book: Proceedings of the 18th IFAC World Congress 2011. Also available from the publisher at: http://dx.doi.org/10.3182/20110828-6-IT-1002.01192 In this paper, a control strategy to reduce the vibrational response of adjacent buildings under seismic excitation is presented. The proposed strategy combines passive linking elements with an active decentralized H∞ control system. The overall active-passive control system admits decentralized design and operation, and achieves an excellent vibrational reduction when the active control system works; in case of a full or partial failure of the active control system, a remarkable reduction in the vibrational res…