Search results for "TSG"
showing 10 items of 38 documents
ESCRT Requirements for Murine Leukemia Virus Release
2016
The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding. To determine the minimal requirements for ESCRT factors in MLV viral and viral-like particles (VLP) release, an siRNA knockdown screen of ESCRT(-associated) proteins was performed in MLV-producing human cells. We found that MLV VLPs and virions primarily engage the ESCRT-I factor Tsg101 and marginally the ESCRT-associated adaptors Nedd4-1 and Alix to enter the ESCRT pathway. Conversely, the inactivation of ESCRT-II had no impact on VLP and virion egress. By analyzing the effects of individual ESCRT-III knockdowns, VLP and virion releas…
Echovirus 1 infection depends on biogenesis of novel multivesicular bodies
2011
Summary Non-enveloped picornavirus echovirus 1 (EV1) clusters its receptor α2β1 integrin and causes their internalization and accumulation in α2β1 integrin enriched multivesicular bodies (α2-MVBs). Our results here show that these α2-MVBs are distinct from acidic late endosomes/lysosomes by several criteria: (i) live intra-endosomal pH measurements show that α2-MVBs are not acidic, (ii) they are not positive for the late endosomal marker LBPA or Dil-LDL internalized to lysosomes, and (iii) simultaneous stimulation of epidermal growth factor receptor (EGFR) and α2β1 integrin clustering leads to their accumulation in separate endosomes. EGFR showed downregulation between 15 min and 2 h, where…
"Table 20" of "Observation of electroweak $W^{\pm}Z$ boson pair production in association with two jets in $pp$ collisions at $\sqrt{s} =$ 13 TeV wit…
2019
Measured $W^{pm}Zjj$ differential cross-section in the VBS fiducial phase space. The relative uncertainties are reported as percentages. The systematic uncertainties are in order of appearance: total uncorrelated systematic and correlated systematics related respectively to unfolding, electrons, muons, jets, reducible and irreducible backgrounds, pileup and luminosity. the last bin is a cross section for all events above the lower end of the bin.
"Table 21" of "Observation of electroweak $W^{\pm}Z$ boson pair production in association with two jets in $pp$ collisions at $\sqrt{s} =$ 13 TeV wit…
2019
Correlation matrix for the unfolded fiducial cross-section.
Das Buch der Güter Livlands und Oesels
1863
Walmeermahzitajmuischs Protokollgrahmata
1850
Livländische Process-Ordnung
1701
Der Königlichen Stadt Riga Gerichts-Ordnung und Statuta
1800
Vidzemes Lielais Zviedru Kadastrs kā saimniecības vēstures avots
1942
Kadastrs - sistematizēti kādu zemes vai ūdens nogabalu vai citu objektu dati; ar nodokļiem apliekamo zemju saraksts un novērtējums pilsētās un laukos. Zemes kadastru sāka ar zemes uzmērīšanu un vērtēšanu, vienlaikus veicot muižu redukciju, atsavinot lielāko daļu muižas zemju, kuras nodeva Zviedrijas valsts pārziņā. Tas bija labi izstrādāts kadastrs, un to izmantoja no 1691. līdz 1911. gadam, t. i., 220 gadus. Tas pasaulē ir samērā mazpazīstams, un tagadējās Latvijas un Igaunijas teritorijā tam bija tikai lokāla nozīme. Muižu redukcija .17. gs. 2. pusē, pieaugot absolūtisma tendencēm Eiropā, Zviedrijas karalis Kārlis XI (Karl XI) centās nostiprināt varu visā valstī. Viens no pasākumiem bija …