Search results for "Tact"
showing 10 items of 1313 documents
Monenkeskinen yhteistyö ja minilateralismi käytännössä : tapauksena Somalian rannikon merirosvous
2022
Artikkelissa pohditaan monenkeskisyyden ilmenemistä minilateraalin yhteistyön kautta. Historiallisesti merirosvous on ollut ajoittain ja alueellisesti esiin nouseva ilmiö, joka ponnistaa paikallisista olosuhteista ja erityisesti heikosta hallinnosta maa-alueilla. Merirosvoukseen liittyvä kansainvälinen sopimusyhteistyö painottaa valtioiden suvereniteetin merkitystä omilla aluevesillään. Käytännössä merten turvallisuuden ymmärtäminen laaja-alaisena ilmiönä sekä merirosvouksen tehokas torjuminen on vaatinut ja vaatii myös jatkossa tiivistä valtioiden välistä yhteistyötä, jossa yksittäisen valtion toimintakykyä kompensoidaan yhteistyön keinoin. Artikkelissa kuvataan kansainvälisen yhteisön pyr…
Suicide and depression in former contact sports participants: population-based cohort study, systematic review, and meta-analysis
2022
SummaryBackgroundTraumatic brain injury is associated with the future risk of depression and suicide, and this raises the possibility that former participants in sports characterised by low intensity repetitive head impact may also subsequently experience an increased burden of these mental health outcomes. Using new data from a cohort study integrated into a meta-analysis of the current evidence, we compared the occurrence of depression and suicide in former contact sports athletes against general population controls.MethodsThe cohort study comprised 2004 retired male athletes who had competed internationally on an amateur basis for Finland between 1920 and 1965, and 1385 age-equivalent ma…
Plasma membrane glycoproteins covalently bound to silica beads as a model for molecular studies of cell-cell interactions in culture.
1987
Abstract In previous studies, we have shown that plasma membrane glycoproteins are of major importance in the density-dependent regulation of growth of normal diploid fibroblasts. Due to the hydrophobic portions of these molecules, functional studies in cell culture are often diffucult to perform and to interpret. Specially, the addition of these molecules in soluble form to cell culture, after depletion of detergents needed for their solubilization, leads to aggregation and internalization. Therefore, we developed a method for the covalent immobilization of the solubilized plasma membrane proteins to derivatized silica beads for further investigations on the molecular nature of the active …
Where lol is: function and position of lol used as a discourse marker in YouTube comments
2020
Lol is probably one of the most popular words in computer-mediated communication. It is generally taken to be the acronym of “laughing out loud”, but it is not always used to indicate a humorous response; rather, it is multifunctional. Drawing on previous studies of the different functions of lol, this paper explores a possible correlation between the position and function of non-lexicalized lol in the specific context of YouTube comments. The hypothesis is that the function of lol largely depends on its position: clause-initial lol is not used with the same functions as clause-final lol. The data for the study come from the comment threads of three popular YouTube videos posted in 2017, 20…
Der Zerfall des Schriftdeutschen im Estado Novo?
2017
Zusammenfassung Der folgende Beitrag beschäftigt sich mit Sprechern des Hunsrückischen in Brasilien und deren Gebrauch des Schriftdeutschen im 20. Jahrhundert. Basis der Analyse ist ein Korpus von Privatbriefen, die während der ersten Diktatur geschrieben wurden. Der Fokus der Analyse ist die Frage nach einer uniformen Schriftnorm für diese Sprechergruppe, deren Muttersprache fast ausschließlich mündlich verwendet wurde. Es wird argumentiert, dass der Estado Novo nicht die einzige Ursache für den Dachsprachenwechsel vom Deutschen zum Portugiesischen war, jedoch entscheidend dazu beigetragen hat, dass die Etablierung einer brasilianischen Schriftnorm des Deutschen endgültig verhindert wurde.…
The global flood of COVID-19 contact tracing apps: sailing with human rights and data protection standards against the wind of mass surveillance
2021
Research background: Countries all around the world are rapidly introducing contact tracing apps and other surveillance technologies to tackle the spread of COVID-19 raising serious concerns about human rights and democratic principles. Purpose of the article: The article aims to analyse how human rights and data protection law regulate the COVID-19 contact tracing apps and reveal the biggest challenges that countries face in applying the essential requirements. Methods: The article will analyse the legal framework and compare many guidance documents issued by the international organisations, including the Council of Europe, the OECD and many EU institutions on the data protection requireme…
How shall we all live together?: Meta‐analytical review of the mutual intercultural relations in plural societies project
2021
Living together in culturally plural societies poses numerous challenges for members of ethnocultural groups and for the larger society. An important goal of these societies is to achieve positive intercultural relations among all their peoples. Successful management of these relations depends on many factors including a research-based understanding of the historical, political, economic, religious and psychological features of the groups that are in contact. The core question is ‘how we shall we all live together?’ In the project reported in this paper (Mutual Intercultural Relations in Plural Societies; MIRIPS), we seek to provide such research by reviewing three core psychological hypoth…
Data from: Evolution of alternative male morphotypes in oxyurid nematodes: a case of convergence?
2014
Male dimorphism has been reported across different taxa, and is usually expressed as the coexistence of a larger morph with exaggerated male traits and a smaller one with reduced traits. The evolution and maintenance of male dimorphism are still poorly understood for several of the species in which it has been observed. Here, we analyse male dimorphism in several species of reptile parasitic nematodes of the genus Spauligodon, in which a major male morph (exaggerated morph), which presents the traditional male morphological traits reported for this taxon, coexists with a minor morph with reduced morphological traits (i.e. reduced genital papillae) resembling more closely the males of the si…
Data from: Intralocus tactical conflict: genetic correlations between fighters and sneakers of the dung beetle Onthophagus taurus
2015
Males and females differ in their phenotypic optima for many traits, and since the majority of genes are expressed in both sexes, some alleles can be beneficial to one sex but harmful to the other (intralocus sexual conflict; ISC). ISC theory has recently been extended to intrasexual dimorphisms, where certain alleles may have opposite effects on the fitness of males of different morphs that employ alternative reproductive tactics (intralocus tactical conflict; ITC). Here we use a half-sib breeding design to investigate the genetic basis for ISC and ITC in the dung beetle Onthophagus taurus. We found positive heritabilities and intersexual genetic correlations for almost all traits investig…
Antithrombotics and new interventions for venous thromboembolism: Exploring possibilities beyond factor IIa and factor Xa inhibition.
2021
Abstract Direct oral anti–activated factor X and antithrombin agents have largely replaced vitamin K antagonists as the standard of care in treatment of venous thromboembolism. However, gaps in efficacy and safety persist, notably in end‐stage renal disease, implantable heart valves or assist devices, extracorporeal support of the circulation, and antiphospholipid syndrome. Inhibition of coagulation factor XI (FXI) emerges as a promising new therapeutic target. Antisense oligonucleotides offer potential advantages as a prophylactic or therapeutic modality, with one dose‐finding trial in orthopedic surgery already published. In addition, monoclonal antibodies blocking activation and/or activ…