Search results for "Tau"
showing 10 items of 4585 documents
Helping lecturers address and formulate teaching challenges: an exploratory study
2018
International audience; In this paper we present an exploratory study on the kind of questions or difficulties lecturers point out at the beginning of an educational course – to be addressed in it. These questions happen to be very general and are poorly connected to the knowledge to be taught. We suggest a twofold interpretation of this phenomenon. On the one hand, and in the line of the didactic transposition theory, teachers do not allow themselves to raise questions about the knowledge that is supposed to be their main field of expertise. On the other hand, the prevailing institutional pedagogy does not provide teachers with a fruitful enough conceptual frame to formulate this kind of q…
Old towns in “smart cities” between conservation and metamorphosis. Pending European Union guidelines
2014
In reflecting upon the role of environmental capital as represented by old towns in smart cities, the author reveals the consequences of re-plastering the facade of ancient buildings while emphasizing the resulting risk of globalization of historic districts. This is followed by a critical consideration concerning the active protection of old towns and their cultural typicality and geographical context, prerequisites for the development of specific guide-lines for the European Union. Explanation is also provided about how the restoration dynamics of the old towns are irreversibly changing the urban landscape in European cities. Strict regulations regarding the preservation of European old t…
Theoretical electronic spectra of 2-aminopurine in vapor and in water
2006
The accurate quantum chemical CASSCF and CASPT2 methods combined with a Monte Carlo procedure to mimic solvation effects have been used in the calculation of the spectroscopic properties of two tautomers of 2-aminopurine (2AP). Absorption and emission spectra have been simulated both in vacuum and in aqueous environment. State and transition energies and properties have been obtained with high accuracy, leading to the assignment of the most important spectroscopic features. The lowest-lying 1 (,*) ( 1 La) state has been determined as responsible for the first band in the absorption spectrum and also for the strong fluorescence observed for the system in water. The combined approach used in …
Obstructive sleep apnea and Alzheimer’s disease-related cerebrospinal fluid biomarkers in mild cognitive impairment
2020
Abstract Previous studies have demonstrated that sleep-breathing disorders, and especially obstructive sleep apnea (OSA), can be observed in patients with a higher risk of progression to Alzheimer’s disease (AD). Recent evidence indicates that cerebrospinal fluid (CSF) AD-biomarkers are associated with OSA. In this study, we investigated these associations in a sample of patients with mild cognitive impairment (MCI), a condition that is considered the first clinical phase of AD, when patients showed biomarkers consistent with AD pathology. A total of 57 patients (mean age = 66.19; SD = 7.13) with MCI were included in the study. An overnight polysomnography recording was used to assess objec…
Airborne birch pollen in Poland and Latvia in the light of data obtained from aerobiological monitoring and tauber traps in relation to mean air temp…
2012
Birch pollen contains allergens belonging to those with the strongest allergenic properties. In order to trace pollen season patterns of this taxon and pollen annual sums at a wider regional scale, cooperation was established with the University of Latvia in Riga (Latvia). A comparison of the results obtained in the years 2003-2008 in Lublin and in Riga, using volumetric samplers, shows that there was a similar trend in the abundance of birch pollen. The highest sums were noted at both sites in 2003. In all the study years, more birch pollen grains were recorded in Lublin than in Riga, on the average by 7110. The birch pollen seasons started earlier in Lublin than in Riga, on the average by…
REM sleep behavior disorder in a patient with frontotemporal dementia
2010
We describe a patient with frontotemporal dementia (FTD), a tauopathy, who also showed clinical and polysomnographic features of REM sleep behavior disorder (RBD). The patient is a 78-year-old male with a 1 year history of behavioral dysfunction involving emotion, character and social functioning. Brain imaging and the results of neuropsychological testing were consistent with a diagnosis of FTD. Sleep symptom onset occurred some years before the behavioral changes, and consisted of unpleasant dreams, vocalization, and prominent motor behaviors. A polysomnography confirmed the diagnosis of RBD. Our findings support the hypothesis that RBD, although more frequent in synucleinopathies, might …
Social Desirability Bias among Prejudice Instruments : An Integrated Threat
2019
A considerable amount of research has examined the extent to which members of dominant cultures perceive minority groups as threatening their way of life. While various instruments measure these perceptions of threat, few researchers have empirically analysed the statistical properties of these scales. Specifically, studies have not adequately explored social desirability of threat scales. The current study investigates the extent to which one set of threat scales is internally consistent or reliable (González et al., 2008), and explores social desirability within the González et al. (2008) integrated threat instruments by comparing self-reports to other reports (intimate other and friend r…
Combined effect of sauna bathing and cardiorespiratory fitness on the risk of sudden cardiac deaths in Caucasian men : a long-term prospective cohort…
2018
Both cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) are each strongly and independently associated with sudden cardiac death (SCD) risk. However, the combined effect of CRF and FSB on SCD risk has not been previously investigated. We evaluated the joint impact of CRF and FSB on the risk of SCD in the Kuopio Ischemic Heart Disease prospective cohort study of 2291 men aged 42–61 years at recruitment. Objectively measured CRF and self-reported sauna bathing habits were assessed at baseline. CRF was categorized as low and high (median cutoffs) and FSB as low and high (defined as ≤2 and 3–7 sessions/week respectively). Multivariable adjusted hazard ratios (HRs) with confide…
Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children : the PANIC study
2022
Objective: Cardiorespiratory fitness has been inversely associated with cardiovascular risk across the lifespan. Some studies in adults suggest that higher cardiorespiratory fitness is associated with cardioprotective metabolite profile, but the evidence in children is lacking. Therefore, we investigated the cross-sectional association of cardiorespiratory fitness with serum nuclear magnetic resonance derived metabolic biomarkers in children. Methods: A population sample of 450 children aged 6–8 years was examined. Cardiorespiratory fitness was assessed by a maximal exercise test on a cycle ergometer and quantified as maximal power output normalised for lean body mass assessed by dual-energ…