Search results for "Terpene"

showing 10 items of 816 documents

Anti-inflammatory glycoterpenoids from Scrophularia auriculata.

2000

The activity of the four glycoterpenoids: two saponins, verbascosaponin A and verbascosaponin, and two iridoids, scropolioside A and scrovalentinoside, isolated from Scrophularia auriculata ssp. pseudoauriculata, were studied in different models of acute and chronic inflammation. Both saponins significantly inhibited the mouse paw edema induced by carrageenan and ear edema induced by single and multiple doses of 12-O-tetradecanoylphorbol 13-acetate (TPA). Verbascosaponin A showed a potency twice as high as that of indomethacin in the acute TPA model. Verbascosaponin A and scropolioside A were active after a long latency period against ethyl phenylpropiolate edema, as are glucocorticoids. Wh…

Serotoninmedicine.drug_classAnti-Inflammatory AgentsInflammationPharmacognosyPharmacologyAnti-inflammatoryCapillary Permeabilitychemistry.chemical_compoundMiceGlucosidesEdemaMedicineAnimalsEdemaHypersensitivity DelayedIridoidsGlycosidesPyransPharmacologyPlants Medicinalbiologybusiness.industryTerpenesBiological activityEarScrophularia auriculataSaponinsbiology.organism_classificationTriterpenesCarrageenanMechanism of actionchemistryImmunologyIridoid GlycosidesTetradecanoylphorbol AcetateFemalemedicine.symptombusinessEuropean journal of pharmacology
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Two new sesquiterpene lactones from Montanoa tomentosa ssp. microcephala

2001

Sesquiterpene lactones Antiproliferative activitySettore BIO/14 - Farmacologia
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Inhibitory Activity and Chemical Characterization ofDaucus carotasubsp.maximusEssential Oils

2017

The essential oils (EOs) of green seeds from Daucus carota subsp. maximus growing wild in Pantelleria Island (Sicily, Italy) were characterized. EOs were extracted by steam distillation, examined for their inhibitory properties against food-borne Gram-positive and Gram-negative bacteria and analyzed for the chemical composition by gas chromatography (GC) and mass spectrometry (MS). Undiluted EOs showed a large inhibition spectrum against Gram-positive strains and also vs. Acinetobacter spp. and Stenotrophomonas maltophilia. The minimum inhibition concentration (MIC) was in the range 1.25 – 2.50 μl/ml for the most sensitive strains. The chemical analysis indicated that D. carota subsp…

Sesquiterpene0301 basic medicineSettore AGR/05 - Assestamento Forestale E SelvicolturaMonoterpeneChemical compositionMonoterpeneSettore MED/42 - Igiene Generale E Applicata01 natural sciencesBiochemistryEssential oilCarotollaw.inventionchemistry.chemical_compoundlawFood scienceChemical compositionInhibitory activitiebiologyChemistry (all)General MedicineAnti-Bacterial AgentsDaucus carotaStenotrophomonas maltophiliaSeedsMolecular MedicineSesquiterpenes030106 microbiologyBioengineeringPyrogallolGram-Positive BacteriaSesquiterpeneSteam distillation03 medical and health sciencesAnti-Bacterial AgentGram-Negative BacteriaBotanyChemical composition; Daucus carota; Essential oils; Foodborne bacteria; Inhibitory activities; Anti-Bacterial Agents; Daucus carota; Gram-Negative Bacteria; Gram-Positive Bacteria; Monoterpenes; Oils Volatile; Pyrogallol; Seeds; Sesquiterpenes; Bioengineering; Chemistry (all); Biochemistry; Molecular Medicine; Molecular BiologyOils VolatileMolecular BiologySeed010405 organic chemistryGeneral ChemistryFoodborne bacteriabiology.organism_classification0104 chemical sciencesMonocyclic SesquiterpeneschemistryMonoterpenesGas chromatographySettore AGR/16 - Microbiologia AgrariaDaucus carotaChemistry & Biodiversity
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Chemical composition of the essential oil of Moluccella spinosa L. (Lamiaceae) collected wild in Sicily and its activity on microorganisms affecting …

2015

In this study the chemical composition of the essential oil from aerial parts of Moluccella spinosa L. collected in Sicily was evaluated by GC and GC-MS. The main components of M. spinosa L. were α-pinene (26.6%), caryophyllene oxide (16.8%) and β-caryophyllene (8.6%). A comparison with other studied oils of genus Moluccella is made. Antibacterial and antifungal activities against some microorganisms infesting historical textiles were also determined.

SesquiterpeneAntifungal AgentsTextileMoluccellaMicroorganismcaryophyllene oxideMoluccella spinosaMonoterpenePlant ScienceMicrobial Sensitivity TestsPlant OilBiochemistryAnalytical Chemistrylaw.inventionGenuslawAnti-Bacterial AgentBotanyOils VolatileAntifungal AgentPlant OilsMoluccella spinosaChemical compositionSicilyEssential oilBicyclic MonoterpenesPolycyclic SesquiterpenesLamiaceaebiologyMicrobial Sensitivity TestMedicine (all)Textilesβ-caryophylleneOrganic ChemistryPlant Components Aerialbiology.organism_classificationantibacterial and antifungal activityα-pineneAnti-Bacterial Agentsvolatile componentCaryophyllene oxideMonoterpenesLamiaceaeSesquiterpenesNatural product research
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Chemical composition of the essential oils of Centaurea tomentella Hand.-Mazz. and C. haussknechtii Boiss. (Asteraceae) collected wild in Turkey and …

2018

In the present study the chemical composition of the essential oils from aerial parts of Centaurea tomentella Hand.-Mazz. and C. haussknechtii Boiss. collected in Turkey was evaluated by GC and GC-MS. The main components of C. tomentella L. were hexadecanoic acid (19.7%), caryophyllene oxide (6.6%) and spathulenol (4.8%) whereas C. haussknechtii was rich in hexadecanoic acid (26.2%), (Z,Z)-9,12-octadecadienoic acid (19.3%), heptacosane (5.3%) and nonacosane (5.1%). Antibacterial and antifungal activities against some microorganisms infesting historical art craft, were also determined.

SesquiterpeneAntifungal AgentsTurkeyMicroorganismPharmacology toxicologycaryophyllene oxideAlkaneCentaureaPlant ScienceMicrobial Sensitivity Tests01 natural sciencesBiochemistryGas Chromatography-Mass SpectrometryAnalytical ChemistryBotanyAnti-Bacterial AgentAlkaneshexadecanoic acidOils VolatileAntifungal Agentantibacterial and Antifungal activityChemical compositionPolycyclic SesquiterpenesbiologyCentaurea tomentellaPolycyclic Sesquiterpene010405 organic chemistryMicrobial Sensitivity TestOrganic ChemistryCentaurea tomentellaSettore CHIM/06 - Chimica OrganicaAsteraceaebiology.organism_classification0104 chemical sciencesAnti-Bacterial Agents010404 medicinal & biomolecular chemistryvolatile componentCaryophyllene oxideCentaureaGas chromatography–mass spectrometry(ZZ)-912-octadecadienoic acidCentaurea haussknechtiiSesquiterpenesArtNatural product research
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Composition of the essential oil of allium neapolitanum cirillo growing wild in sicily and its activity on microorganisms affecting historical art cr…

2015

Essential oil of the aerial parts of Allium neapolitanum Cirillo collected in Sicily were analyzed by gas-chromatography-flame-ionization detection and gas-chromatography-mass spectrometry. Nineteen compounds were identified in the oil and the main components were found to be (E)-chrysanthenyl acetate (28.1%), (Z)-chrysanthenyl acetate (23.8%), (E)-β-farnesene (9.6%), dimethyl trisulfide (9.6%), camphor (7.4%), methyl allyl disulfide (6.8%) and 1-methyl-3-allyl trisulfide (5.8%). The essential oil showed good antimicrobial activity against 11 strains of test microorganisms, including several species infesting historical material.

SesquiterpeneGeneral Chemical EngineeringAllyl compoundMonoterpeneAntimicrobial activityPlant OilEssential oillaw.inventionCamphorchemistry.chemical_compoundlaw(E)-chrysanthenyl acetateChemical Engineering (all)DisulfidesFood scienceMedicinal plantsSicilyFlame IonizationbiologyChemistry (all)food and beveragesGeneral MedicineAntimicrobialAllyl CompoundsArtifactAlliumArtifactsSesquiterpenesArt(Z)-chrysanthenyl acetateSulfideAllium neapolitanumSulfidesGas Chromatography-Mass SpectrometryAlliumBridged Bicyclo CompoundsDisulfideDrug Resistance FungalBotanyDrug Resistance BacterialOils VolatilePlant OilsAllium neapolitanumEssential oilBacteriaFungiGeneral ChemistryPlant Components Aerialbiology.organism_classificationCamphorchemistryMonoterpenesBridged Bicyclo CompoundDimethyl trisulfideAllyl Compound
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Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer population from Spain

2012

[EN] The essential oil composition of Cistus ladanifer grown in central Spain was analysed by gas chromatography and gas chromatography/mass spectrometry, revealing it to be rich in oxygenated compounds, with trans-pinocarveol (20.00%), bornyl acetate (7.03%) and terpinen-4-ol (6.37%) as the main monoterpene compounds. Viridiflorol (13.59%) and ledol (4.36%) were the main constituents of the oxygenated sesquiterpene fraction. Large amounts of-pinene (4.70%) were found in the hydrocarbonated fractions. To study its possible use as a natural herbicide, the oil was tested invitro against Amaranthus hybridus, Portulaca oleracea, Chenopodium album, Conyza canadensis and Parietaria judaica, compl…

SesquiterpeneHerbicidal activityLedolUnclassified drugAmaranthus hybridusPineneTerpinen 4 olChemical compositionAmaranthus hybridusPlant ScienceBiochemistryCistus ladaniferEssential oilAnalytical Chemistrylaw.inventionChenopodium albumchemistry.chemical_compoundLedollawBornyl acetateBicyclic MonoterpenesBIOLOGIA VEGETALeducation.field_of_studyAmaranthusbiologyGC/MSCistusPortulacaceaeConyza canadensisGerminationCistus ladaniferPinocarveolHerbicideTerpene derivativeChromatography GasPopulationBOTANICAMass fragmentographyGerminationPortulacaArticleGas Chromatography-Mass SpectrometryChenopodiumCistusBotanyOils VolatileeducationEssential oilHerbicidesOrganic ChemistryTerpinen-4-olCistaceaebiology.organism_classificationWeedParietaria judaicaParietariachemistrySpainViridiflorolMonoterpenesWeedsConyza
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Chemical composition of the essential oil of Jacobaea maritima (L.) PelserMeijden and Jacobaea maritima subsp. bicolor (Willd.) B. Nord.Greuter (Aste…

2015

In this study, the chemical compositions of the essential oils from aerial parts (JmA) and radices (JmR) of Jacobaea maritima (L.) Pelser & Meijden, collected in Croatia, and of Jacobaea maritima subsp. bicolor (Willd.) B. Nord. & Greuter, collected in Sicily, were evaluated by using gas chromatography and gas chromatography–mass spectrometry. The main components of the essential oil from J. maritima, both in JmA and JmR, were pentacosane (15.7%), heptacosane (13.1%) and nonacosane (8.1%) whereas the essential oil from J. maritima subsp. bicolor was characterised by the presence of hexadecanoic acid (14.6%), caryophyllene oxide (9.3%) and hexahydrofarnesylacetone (6.5%). The comparison of t…

SesquiterpeneJacobaea maritimaCroatiaNonacosanecaryophyllene oxideAlkanePalmitic AcidJacobaea maritima subsp. bicolorPlant ScienceAsteraceaePlant OilBiochemistryGas Chromatography-Mass Spectrometrylaw.inventionAnalytical Chemistrychemistry.chemical_compoundhydrocarbonGenuslawBotanyAlkaneshexadecanoic acidOils VolatilePlant OilsChemical compositionSicilyEssential oilPolycyclic SesquiterpenesbiologyJacobaeaOrganic ChemistryJacobaea maritimaAsteraceaebiology.organism_classificationJacobaea maritima; Jacobaea maritima subsp. bicolor; Asteraceae; volatile components; hydrocarbons; hexadecanoic acid; caryophyllene oxidevolatile componentchemistryCaryophyllene oxidebacteriaSesquiterpenesNatural product research
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Chemical composition of volatile and fixed oils from of Salvia argentea L. (Lamiaceae) growing wild in Sicily.

2015

The chemical compositions of the essential oil and of the non-polar extracts (petroleum ether, dichloromethane) of the aerial parts (flowers, leaves and stems) of Salvia argentea L. were determined by GC-FID and gas chromatography–mass spectrometry analysis. 14-Hydroxy-α-humulene (40.1%) was recognised as the main constituents of the essential oil of S. argentea, together with 1,3,8-p-menthatriene (12.1%), globulol (7.4%) and β-sesquiphellandrene (5.8%). Tritriacontane (9.9% and 14.1%), heptacosane (8.4% and 10.5%), hentriacontane (8.3% and 10.9%), tetradecanal (8.4% and 10.2%) and methyldotriacontane (7.9% and 7.6%) were recognised as the main constituents of the extracts in petroleum …

SesquiterpeneLinolenic AcidsPlant ScienceSalvia argentea01 natural sciencesBiochemistrylaw.inventionAnalytical ChemistryFatty Acids Monounsaturatedchemistry.chemical_compoundlawfixed oilPetroleum etherSettore BIO/15 - Biologia FarmaceuticaSalviaSicilyHentriacontanebiologyTraditional medicineChemistryvolatile componentPetroleumFlowerParaffinLinolenic AcidPlant LeaveSesquiterpenesLinolenic acidFlowersSalviaGas Chromatography-Mass Spectrometry14-hydroxy-α-humulenePlant ExtractBotanyOils VolatileEssential oilLamiaceae010405 organic chemistryPlant ExtractsOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classification0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistrySalvia argenteaSettore BIO/03 - Botanica Ambientale E ApplicataLamiaceaefatty acidGas chromatography–mass spectrometryNatural product research
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The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells

2014

Abstract: The sesquiterpene lactone Parthenolide (PN) exerted a cytotoxic effect on MDA-MB231 cells, a triple-negative breast cancer (TNBC) cell line, but its effectiveness was scarce when employed at low doses. This represents an obstacle for a therapeutic utilization of PN. In order to overcome this difficulty we associated to PN the suberoylanilide hydroxamic acid (SAHA), an histone deacetylase inhibitor. Our results show that SAHA synergistically sensitized MDA-MB231 cells to the cytotoxic effect of PN. It is noteworthy that treatment with PN alone stimulated the survival pathway Akt/mTOR and the consequent nuclear translocation of Nrf2, while treatment with SAHA alone induced autophagi…

SesquiterpenePhysiologyClinical BiochemistryDown-RegulationApoptosisBreast NeoplasmsApoptosis; Autophagy; Breast Neoplasms; Cell Line Tumor; Down-Regulation; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; NF-kappa B; Sesquiterpenes; Clinical Biochemistry; Cell Biology; Physiology; Medicine (all)Hydroxamic AcidsHydroxamic AcidSettore BIO/10 - BiochimicaCell Line TumorHistone Deacetylase InhibitorAutophagyHumansBiologyVorinostatMedicine (all)NF-kappa BApoptosiDrug SynergismCell BiologyHistone Deacetylase InhibitorsFemaleHuman medicineSesquiterpenesBreast NeoplasmHumanJournal of cellular physiology
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