Search results for "Terpene"

showing 10 items of 816 documents

Retinoids induce MMP-9 expression through RARalpha during mammary gland remodeling.

2007

Retinoic acid (RA) is a signaling molecule in the morphogenesis of the mammary gland, modulating the expression of matrix metalloproteinases (MMPs). The aim of this paper was to study the role of RA during weaning, which consists of three events: apoptosis of the secretory cells, degradation of the extracellular matrix, and adipogenesis. CRABP II and CRBP-1 carrier proteins increased significantly during weaning compared with lactating glands but reverted to control values after the litter resuckled. The effects of RA are mediated by the nuclear receptors RARalpha, RARbeta, RARgamma, and RXRalpha, which underwent an increase in protein levels during weaning. In an attempt to elucidate the R…

medicine.medical_specialtyRetinyl EstersTime FactorsPhysiologymedicine.drug_classReceptors Retinoic AcidEndocrinology Diabetes and MetabolismMammary glandMorphogenesisRetinoic acidApoptosisTretinoinWeaningMatrix metalloproteinaseBiologyStromelysin 1chemistry.chemical_compoundRetinoidsMammary Glands AnimalPregnancyPhysiology (medical)Internal medicinemedicineAnimalsLactationInvolution (medicine)RetinoidRNA MessengerRats WistarVitamin AMammary gland involutionAdipogenesisRetinoic Acid Receptor alphaRetinol-Binding Proteins CellularMatrix MetalloproteinasesExtracellular MatrixRatsRetinol-Binding Proteinsmedicine.anatomical_structureEndocrinologychemistryMatrix Metalloproteinase 9Matrix Metalloproteinase 2FemaleDiterpenesSignal TransductionAmerican journal of physiology. Endocrinology and metabolism
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Reuse of Food Waste: The Chemical Composition and Health Properties of Pomelo (Citrus maxima) Cultivar Essential Oils

2022

The aim of the present study is to investigate the chemical profile, antioxidant activity, carbohydrate-hydrolysing enzyme inhibition, and hypolipidemic effect of essential oils (EOs) extracted from Sicilian Citrus maxima (pomelo) flavedo. Using gas-chromatography-mass spectrometry analysis (GC-MS) we analysed the Eos of five cultivars of C. maxima, namely, ‘Chadock’, ‘Maxima’, ‘Pyriformis’, ‘Terracciani’, and ‘Todarii’, and their blends. The antioxidant activity was performed by using a multi-target approach using 2,2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS), 2,2-Diphenyl-1-picrylhydrazyl (DPPH), ferric reduc…

monoterpene hydrocarbonscarbohydrate-hydrolysing enzymesOrganic ChemistryPharmaceutical SciencePCA and HCA analyses‘recirculate’gas chromatography-mass spectrometryAnalytical ChemistryCitrus maxima (Burm.) Merr<i>Citrus maxima</i> (Burm.) Merr.; gas chromatography-mass spectrometry; monoterpene hydrocarbons; ‘recirculate’; PCA and HCA analyses; carbohydrate-hydrolysing enzymes; lipaseChemistry (miscellaneous)Drug DiscoverylipaseMolecular MedicinePhysical and Theoretical Chemistry
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Effect of Germacrene-Rich Essential Oil of Parentucellia latifolia (L.) Caruel Collected in Central Sicily on the Growth of Microorganisms Inhabiting…

2022

In the present study, the chemical composition of the essential oil from aerial parts of Parentucellia latifolia (L.) Caruel collected in Central Sicily was analyzed by gas chromatography and gas chromatography–mass spectrometry. The results showed the presence of sesquiterpene hydrocarbons, with germacrene D and germacrene B accounting, respectively, for 59.2% and 24.3% of the total oil. Different colonies of bacteria and fungi frequently affect cellulosic objects such as books stored in libraries and museums. The antibacterial and antifungal activity against some microorganisms infesting historical-artistic craftsmanship was determined, demonstrating that the essential oil was particular…

orobanchaceaePharmacologyantibacterial and antifungal activitiesComplementary and alternative medicinesesquiterpene hydrocarbonsDrug Discoveryantibacterial and antifungal activitiePlant ScienceGeneral MedicineParentucellia latifoliagermacreneessential oilNatural Product Communications
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Identification of Brassicadiene, a Diterpene Hydrocarbon Attractive to the Invasive Stink Bug Bagrada hilaris, from Volatiles of Cauliflower Seedling…

2020

Brassicadiene, a novel tricyclic diterpene hydrocarbon, was identified by a combination of mass spectrometry, microchemical tests, and analysis of NMR spectra. The compound constitutes &gt;90% of the volatile organic compounds produced by cauliflower seedlings, Brassica oleracea var. botrytis. The invasive stink bug Bagrada hilaris is strongly attracted to brassicadiene, providing a mechanism for this herbivore, which specializes on cruciferous plants, to locate its hosts in a nutrient-rich and vulnerable stage.

painted bugchemistry.chemical_classificationmass spectrometry microchemical tests NMR analysis Y-olfactometer bioassaysBagrada hilarisfood.ingredientbiologyChemistrykairomoneOrganic ChemistryBrassica oleracea var botrytisbiology.organism_classificationBiochemistryditerpene hydrocarbonchemistry.chemical_compoundfoodHydrocarbonSettore AGR/11 - Entomologia Generale E ApplicataBotanyBrassica oleraceaPhysical and Theoretical ChemistryDiterpeneBotrytis
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Natural Ingredients of Transdermal Drug Delivery Systems as Permeation Enhancers of Active Substances through the Stratum Corneum

2023

In recent years, significant progress has been made in transdermal drug delivery systems, but there is still a search for enhancers that can improve the absorption of active substances through the stratum corneum. Although permeation enhancers have been described in the scientific literature, the use of naturally occurring substances in this role is still of particular interest, because they can offer a high level of safety of use, with a low risk of skin irritation, and high efficiency. In addition, these ingredients are biodegradable, easily available, and widely accepted by consumers due to the growing trust in natural compounds. This article provides information on the role of naturally…

penetration enhancersraw materialspolysaccharidesskin barrierfatty acidsterpenesMolecular Pharmaceutics
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Amino acid-­deriving chiral polymers with potential for biotechnological applications

2017

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poly(amidoamine)s chiral polymers interpenetrating peptides
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Isolement et caractérisation de saponosides extraits de deux plantes médicinales : Cyclamen africanum, Zygophyllum cornutum et évalution de leur acti…

2014

The appearance of several diseases, such as cancer, diabetes, high blood pressure and spread of infections mutagenic virus type can be linked to the quality and lifestyle that we lead today. Indeed, several studies on the factors triggering these so-called "morbid" long-or short-term illnesses are related to stress and quality of food consumed, whether of plant and animal origin. These diseases are becoming a common occurrence, they affect different races and all classes of society. According ethnobotanical research, naturally occurring substances, allowed civilizations to survive deadly diseases. For example, we thus find references to periods of malarial fever in China and one of the symp…

protéines réponse inflammatoire (PRI)[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyMass spectrometry1D and 2D NMRZygophyllum cornutumMédiateurs pro-inflammatoire (COX-2)Anti-inflammatoires (AINS)INOSPro-inflammatory mediatorsProtein inflammatory response (PRI)Activité anti inflammatoireAnti inflammatory activitySaponins triterpeneCyclamen africanumCOX-2Spectrométrie de masseRMN 1DRMN 2DSaponines triterpéniques[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyAnti-inflammatory drugs (NSAIDs)TNF -αPGE2[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Pyrolytic formation of polycyclic aromatic hydrocarbons from sesquiterpenes

2012

Author's version of an article in the journal: Food Chemistry. Also available from the publisher at: http://dx.doi.org/10.1016/j.foodchem.2012.06.033 The products of the pyrolysis of four sesquiterpenes, β-caryophyllene, α-cedrene, longifolene and valencene, have been examined. Pyrolysis was carried out at 300, 400 and 500 °C, the products determined by GC–MS and then examined for similarities and differences using multivariate data analysis. Analysis showed that longifolene was most resistant and caryophyllene least resistant to pyrolysis with cedrene and valencene occupying intermediate positions. While the compounds were largely unchanged at 300 °C, polycyclic aromatic hydrocarbons (PAHs…

sesquiterpeneHot TemperatureCedrenePolycyclic aromatic hydrocarbonSesquiterpeneAnalytical Chemistrychemistry.chemical_compoundValencenepolycyclic aromatic hydrocarbonOrganic chemistryPyrolytic carbonPolycyclic Aromatic Hydrocarbonschemistry.chemical_classificationMolecular StructureVDP::Mathematics and natural science: 400::Chemistry: 440CaryophyllenelongifolenePAHGeneral Medicinepyrolysisα-Cedrenechemistryβ-CaryophylleneLongifoleneSesquiterpenesvalencenePyrolysisFood ScienceFood Chemistry
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Comparison of essential oil components and in vitro anticancer activity in wild and cultivated Salvia verbenaca.

2015

The objectives of our research were to study the chemical composition and the in vitro anticancer effect of the essential oil of Salvia verbenaca growing in natural sites in comparison with those of cultivated (Sc) plants. The oil from wild (Sw) S. verbenaca presented hexadecanoic acid (23.1%) as the main constituent, while the oil from Sc plants contained high quantities of hexahydrofarnesyl acetone (9.7%), scarce in the natural oil (0.7%). The growth-inhibitory and proapoptotic effects of the essential oils from Sw and Sc S. verbenaca were evaluated in the human melanoma cell line M14, testing cell vitality, cell membrane integrity, genomic DNA fragmentation and caspase-3 activity. Both t…

sesquiterpenePalmitic AcidApoptosisDNA FragmentationPlant ScienceSalviaPlant OilBiochemistryessential oillaw.inventionAnalytical ChemistryTerpenePalmitic acidchemistry.chemical_compoundfoodlawCell Line TumorBotanymelanomaOils VolatileHumansPlant OilsSalviaFragmentation (cell biology)Essential oilLamiaceaebiologyTraditional medicineSalvia verbenacaTerpenesCaspase 3Medicine (all)Organic ChemistryApoptosibiology.organism_classificationAntineoplastic Agents Phytogenicfood.foodchemistryTerpeneDNA fragmentationSalvia verbenacaLamiaceaeHuman
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Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp. siculum

2012

WOS: 000306752700042

sesquiterpeneeudesmanolidePharmaceutical ScienceFlowersSesquiterpeneArticleChinese hamsterCell LineAnalytical ChemistryHuman lungInhibitory Concentration 50Tanacetumchemistry.chemical_compoundsesquiterpenesDrug DiscoveryBotanymedicineAnimalsHumansCytotoxic T cellSettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryTanacetum vulgarecytotoxic activityCell ProliferationCell DeathbiologyTraditional medicine<em>Tanacetum vulgare</em>; sesquiterpenes; eudesmanolides; cytotoxic activityeudesmanolidesOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationIn vitroTanacetum vulgare; sesquiterpenes; eudesmanolides; cytotoxic activitymedicine.anatomical_structurechemistryPhytochemicalChemistry (miscellaneous)Molecular MedicineColorimetryFormazanMolecules; Volume 17; Issue 7; Pages: 8186-8195
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