Search results for "Testing"

showing 10 items of 1769 documents

Mutation Analysis Identifies GUCY2D as the Major Gene Responsible for Autosomal Dominant Progressive Cone Degeneration

2008

PURPOSE. Heterozygous mutations in the GUCY2D gene, which encodes the membrane-bound retinal guanylyl cyclase-1 protein (RetGC-1), have been shown to cause autosomal dominant inherited cone degeneration and cone–rod degeneration (adCD, adCRD). The present study was a comprehensive screening of the GUCY2D gene in 27 adCD and adCRD unrelated families of these rare disorders. METHODS. Mutation analysis was performed by direct sequencing as well as PCR and subsequent restriction length polymorphism analysis (PCR/RFLP). Haplotype analysis was performed in selected patients by using microsatellite markers. RESULTS. GUCY2D gene mutations were identified in 11 (40%) of 27 patients, and all mutation…

Retinal degenerationMaleDNA Mutational AnalysisReceptors Cell SurfaceBiologyPolymerase Chain ReactionArticlemedicineElectroretinographyMissense mutationHumansGenetic Predisposition to DiseaseCodonGeneGeneticsHaplotypeRetinal DegenerationDNAmedicine.diseasePrognosisRod Cell Outer SegmentMajor geneMolecular biologyPedigreeHaplotypesGuanylate CyclaseMutationMutation testingDisease ProgressionGUCY2DFemaleRestriction fragment length polymorphism
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Commissioning and periodic tests of the Esteya® electronic brachytherapy system

2015

A new electronic brachytherapy unit from Elekta, called Esteya(®), has recently been introduced to the market. As a part of the standards in radiation oncology, an acceptance testing and commissioning must be performed prior to treatment of the first patient. In addition, a quality assurance program should be implemented. A complete commissioning and periodic testing of the Esteya(®) device using the American Association of Physicists in Medicine (AAPM), Groupe Europeen de Curietherapie and the European Society for Radiotherapy & Oncology (GEC-ESTRO) guidelines for linacs and brachytherapy units as well as our personal experience is described in this paper. In addition to the methodology, r…

Review Papermedicine.medical_specialtyTraceabilityPeriodic testingelectronic brachytherapybusiness.industryProject commissioningmedicine.medical_treatmentBrachytherapyquality assuranceTest (assessment)EsteyaOncologyAcceptance testingRadiation oncologyMedicinecommissioningRadiology Nuclear Medicine and imagingMedical physicsbusinessQuality assuranceJournal of Contemporary Brachytherapy
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Optimization of depth increment distribution in the ring-core method

1996

The integral equation method is the most suitable calculation procedure for the determination of non-uniform residual stresses by semi-destructive mechanical methods such as hole and ring-core drilling. However, the high sensitivity to strain measurement errors due to the ill-conditioning of the equation sets has prevented its practical use. Examination of the influence of the strain measurement error on the calculated stresses and its propagation has shown that, for given maximum groove depth and total steps number, the error sensitivity depends on the particular depth increment distribution used. By means of an alternative matrix formulation of the equation sets the depth increment distr…

Ring (mathematics)Applied MathematicsMechanical EngineeringNumerical analysisDrillingGeometryIntegral equationCore (optical fiber)Distribution (mathematics)Mechanics of MaterialsResidual stressModeling and SimulationDestructive testingMathematicsThe Journal of Strain Analysis for Engineering Design
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Experimental determination of viscous damper parameters in low velocity ranges

2017

In the last decades many strategies for seismic vulnerability mitigation of structures have been developed through analytical studies and experimental tests. Among these, energy dissipation by external devices assumes a great relevance for the relative design simplicity, even if applied to complex structures, and the effectiveness in reducing seismic demand. In particular, the use of fluid viscous dampers represents a very attractive solution because of their velocity-dependent behaviour and relatively low costs. The application on structures requires specific study under seismic excitation and a particular care of structural details. In this context the use of proper constitutive models fo…

RiskDissipation; Experimental testing; Fluid viscous dampers; Low velocity; Seismic protection; Building and Construction; Safety Risk Reliability and Quality; Geotechnical Engineering and Engineering GeologyLow velocityFluid viscous damperDissipationReliability and QualityExperimental testingFluid viscous dampersBuilding and ConstructionSafetyGeotechnical Engineering and Engineering GeologySeismic protection
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Risk perception and knowledge of COVID-19 in patients with celiac disease

2021

BACKGROUND We recently demonstrated that the odds of contracting coronavirus disease 2019 (COVID-19) in patients with celiac disease (CeD) is similar to that of the general population. However, how patients with CeD perceive their COVID-19 risk may differ from their actual risk. AIM To investigate risk perceptions of contracting COVID-19 in patients with CeD and determine the factors that may influence their perception. METHODS We distributed a survey throughout 10 countries between March and June 2020 and collected data on demographics, diet, COVID-19 testing, and risk perceptions of COVID-19 in patients with CeD. Participants were recruited through various celiac associations, clinic visi…

RiskMalemedicine.medical_specialtyPopulationObservational StudyDiseaseLogistic regressionOdds03 medical and health sciences0302 clinical medicineCOVID-19 TestingCeliac diseaseMedicineHumansCOVID-19 Celiac disease Coronavirus Gluten Infection Knowledge Perception RiskeducationAgededucation.field_of_studyCOVID-19; Celiac disease; Coronavirus; Gluten; Infection; Knowledge; Perception; Risk; Aged; COVID-19 Testing; Humans; Male; Perception; SARS-CoV-2; COVID-19; Celiac Diseasebusiness.industrySARS-CoV-2Public healthfungiGastroenterologyCOVID-19General MedicineOdds ratioMental healthRisk perceptionCoronavirusCeliac DiseaseKnowledge030220 oncology & carcinogenesis030211 gastroenterology & hepatologyPerceptionbusinessInfectionGlutenDemography
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Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines.

2013

J. Balmana1, F. Balaguer2, A. Cervantes3 & D. Arnold4, on behalf of the ESMO Guidelines Working Group* Department of Medical Oncology, Hospital Vall d’Hebron, Vall d’Hebron Institute of Oncology (VHIO), Universitat Autonoma de Barcelona, Barcelona; Department of Gastroenterology, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Barcelona; Department of Hematology and Medical Oncology, INCLIVA, University of Valencia, Valencia, Spain; Department of Medical Oncology, Tumor Biology Clinic, Albert Ludwigs University, Freiburg, Germany;

Riskmedicine.medical_specialtyColorectal cancerChemopreventionDNA Mismatch RepairDNA GlycosylasesNeoplastic Syndromes Hereditaryhealth services administrationMedicineHumansGenetic Predisposition to DiseaseGenetic TestingMultiple PolypsSigmoidoscopyEarly Detection of CancerAgedTumor biologybusiness.industryBrain NeoplasmsGeneral surgeryHematologyColonoscopyFamilial riskMiddle Agedmedicine.diseaseColorectal Neoplasms Hereditary NonpolyposishumanitiesClinical PracticeEuropeOncologyAdenomatous Polyposis Colipopulation characteristicsFemaleMicrosatellite InstabilitybusinessColorectal NeoplasmsColorectal Surgerygeographic locationsAnnals of oncology : official journal of the European Society for Medical Oncology
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Introducing a new method for efficient visualization of complex shape 3D ultrasonic phased-array C-scans

2017

Automated robotic inspection systems allow the collection of large data volumes, compared to existing inspection systems. To maximize the throughput associated with the non-destructive evaluation phase, it is crucial that the reconstructed inspection data sets are generated and examined rapidly without a loss of detail. Data analysis often becomes the bottleneck of automated inspections. Therefore, new data visualization tools, suitable to screen the NDT information obtained through robotic systems, are urgently required. This paper presents a new approach, for the generation of three-dimensional ultrasonic C-scans of large and complex parts, suitable for application to high data throughput…

Robot kinematicsbusiness.industryComputer sciencePhased arrayTK020207 software engineering02 engineering and technologyRoboticsPhased ArraysVisualizationData visualizationAutomated X-ray inspection020204 information systemsNondestructive testing0202 electrical engineering electronic engineering information engineeringComputer visionUltrasonic sensorArtificial intelligenceAutomated SystemsbusinessThroughput (business)Surface reconstructionC-ScansData Visualisation
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»Was ich am richtigen Leben nicht so schätze« Online-Rollenspielsucht eines Jugendlichen - Fallstudie/ “What I don‘t Appreciate in Real Life”: Online…

2015

The present article aims to provide an insight into the life story of a computer-game addicted adolescent. Here, the relationship between the symptom game addiction, the family as a reference framework, the game's characteristics, as well as the subjective emotional state of the adolescent are of particular interest. An emphasis is also laid on the psychodynamically approached question of the impact of infantile and current relationship experiences (both within a family environment as well as with peers) on personal development. Last, still within a psychodynamic framework, we hope to provide a better understanding of the role of online computer-game addiction in the process of experiences …

Role playing gamebusiness.industryAddictionmedia_common.quotation_subjectSocializationComputingMilieux_PERSONALCOMPUTINGPsychodynamicsReality testingInternal-External ControlPersonal developmentDevelopmental psychologyPsychoanalytic theoryPsychologybusinessmedia_commonPraxis der Kinderpsychologie und Kinderpsychiatrie
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Neoclassical Convergence Versus Technological Catch-Up : A Contribution for Reaching a Consensus.

2004

http://www.businessperspectives.org/files/ppm/PPM_EN_2004_03pp15_42.pdf; International audience; New macro empirical evidence is provided to assess the relative importance of object andidea gaps in explaining the world income distribution dynamics over a benchmark period of 1960-1985. Results are then extended through 1995. Formal statistical hypothesis tests allow us to discriminatebetween two competing growth models: (i) the standard neoclassical growth model similarto that employed by Mankiw, Romer, and Weil (1992), and (ii) an endogenous growth modelclosely related to the Nelson and Phelps' approach (1966) that emphasizes the importance of technologytransfer in addition to factor accumu…

RomerO40jel:C21WachstumstheorieTechnologietransferEconomicsEconometrics[ SHS.ECO ] Humanities and Social Sciences/Economies and financestechnological catch-upand income dynamicsC14income dynamics050207 economicsMacro10. No inequalityEmpirical evidence[SHS.ECO] Humanities and Social Sciences/Economics and FinanceC12050205 econometrics Public economicsO5005 social sciences1. No povertyjel:C12Convergence (economics)[SHS.ECO]Humanities and Social Sciences/Economics and Financeeconomic growthjel:C14jel:O50C21TheorieSchätzungWeltneoclassical convergenceSample (statistics)O5lcsh:BusinessSchumpeterian growthjel:O40Income distribution0502 economics and businessddc:330economic growthneoclassical convergencetechnological catch-upincome dynamicsNeue WachstumstheorieStatistical hypothesis testingO33Endogenous growth theoryendogenous growthjel:O33Entwicklungskonvergenzlcsh:HF5001-6182
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The Evaluation of Four Electronic Apex Locators in Teeth with Simulated Horizontal Oblique Root Fractures

2008

The accuracy of four electronic apex locators (EALs) to locate the apical limit in teeth with simulated horizontal oblique root fractures was investigated. A horizontal oblique incomplete root fracture was simulated on 20 freshly extracted maxillary anterior teeth by means of a notch made on the vestibular root plane 8 mm from the anatomic apex. The EALs investigated were the ProPex (Dentsply Maillefer, Ballaigues, Switzerland), the NovApex (Forum Technologies, Rishon Le-Zion, Israel), the Root ZX (J. Morita Corp, Kyoto, Japan), and the Elements Apex Locator (SybronEndo, Orange CA). The electronic measurements were compared with the real "working length." The accuracy obtained was of 80% (n…

Root planebusiness.industryOblique caseDentistryEquipment DesignMaterials testingTooth ApexElectronics MedicalTooth FracturesTooth rootTooth ApexMaterials TestingHumansOdontometryTooth RootbusinessGeneral DentistryRoot Canal PreparationAnterior teethMathematicsJournal of Endodontics
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