Search results for "Testing"
showing 10 items of 1769 documents
Granular chains for the assessment of thermal stress in slender structures
2015
Slender beams subjected to compressive stress are common in civil and mechanical engineering. The rapid in-situ measurement of this stress may prevent structural anomalies. In this paper, we describe the coupling mechanism between highly nonlinear solitary waves (HNSWs) propagating along an L-shaped granular system and a beam in contact with the granular medium. We evaluate the use of HNSWs as a tool to measure stress in thermally loaded structures and to estimate the neutral temperature, i.e. the temperature at which this stress is null. We investigated numerically and experimentally one and two L-shaped chains of spherical particles in contact with a prismatic beam subjected to heat. We f…
Influence of a Specific Aquatic Program on Social and Gross Motor Skills in Adolescents with Autism Spectrum Disorders: Three Case Reports
2019
Swimming pool activities revealed to be efficacious to train psychomotor skills and increase adaptive behaviors in children with Autism Spectrum Disorders (ASD). Therefore, the purpose of this study was to investigate the efficacy of a specific multi-systemic aquatic therapy (CI-MAT) on gross motor and social skills in three adolescents with Autism Spectrum Disorders (ASD). Methods: three adolescents with ASD of which two boys (M1 with a chronological age of 10.3 years and a mental age of 4.7 years; M2 with a chronological age of 14.6 and a mental age inferior to 4 years) and one girl (chronological age of 14.0 and a mental age inferior to 4 years). The study was divided into three phases: …
Is large-scale rapid CoV-2 testing a substitute for lockdowns?
2021
Background Various forms of contact restrictions have been adopted in response to the Covid-19 pandemic. Around February 2021, rapid testing appeared as a new policy instrument. Some claim it may serve as a substitute for contact restrictions. We study the strength of this argument by evaluating the effects of a unique policy experiment: In March and April 2021, the city of Tübingen set up a testing scheme while relaxing contact restrictions. Methods We compare case rates in Tübingen county to an appropriately identified control unit. We employ the synthetic control method. We base interpretations of our findings on an extended SEIR model. Findings The experiment led to an increase in the …
Ambient Temperature, Social Perception and Social Behavior
2020
The literature suggests that human perception and behavior vary with physical temperature. We provide an experimental test of how different ambient temperature conditions impact social behavior and social perception: Subjects went through a series of tasks measuring various aspects of social behavior and perception under three temperature conditions (cold vs. optimal vs. warm). Despite well-established findings on temperature effects, our data suggest that physical temperature has no relevant influence on social behavior and social perception. We corroborate our finding of a null effect by the use of equivalence testing and provide a discussion in the light of recent failed replication atte…
Time Series Momentum in the US Stock Market: Empirical Evidence and Theoretical Implications
2020
There is much controversy in the academic literature on the presence of short-term trends in financial markets and the trend-following strategy's profitability. This paper restricts its attention to the study of time-series momentum (TSMOM) in the US stock market. The paper aims to suggest answers to several important questions regarding TSMOM and to explain the existing controversy. Our answer to the question, whether short-term trends exist, is strongly affirmative. For the first time, we suppose that the returns follow a p-order autoregressive process with p>1 and evaluate this process's parameters. Fairly accurate knowledge of the momentum generating process allows us to provide analyti…
A new calculation procedure for non-uniform residual stress analysis by the hole-drilling method
1998
The hole-drilling method is one of the most used semi-destructive techniques for residual stress analysis in mechanical parts. In the presence of non-uniform residual stress, the stress field can be determined from the measured relaxed strains using several calculation methods, but the most used one is the so-called integral method. This method is characterized by some simplifications that lead to approximate results, especially when the residual stress varies abruptly. In this paper a new calculation procedure called the spline methods is proposed, which allows these drawbacks to be overcome. Numerical simulations and an experimental test have corroborated the best performance of the prop…
Thermoplastic Properties of Endodontic Gutta-percha: A Thermographic In Vitro Study
2014
Abstract Introduction Endodontic gutta-percha undergoes deformation at temperatures above 65°C. The temperature influence of heat carriers on gutta-percha cones was investigated in vitro. Methods Six single-rooted extracted teeth were embedded in resin and fixed. The root canals were prepared (ProFile; Dentsply Maillefer, Ballaiques, Switzerland) to different tapers and bisected. Thermographic images when heating the gutta-percha cones (Roeko, Langenau, Germany) with a heat carrier (ML .12; SybronEndo, Orange, CA) at 1 and 5 mm from the working length were made with an infrared thermal imaging camera (ThermaCam P640; Flir Systems, Taby, Sweden). The device temperature was preset at 200°C. T…
HPV-DNA Positive/p16 IHC Negative Oral Squamous Cell Carcinoma: A Case Report
2019
LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells
2015
Hepatotoxicity is the number one cause for agencies not approving and withdrawing drugs for the market. Drug-induced human hepatotoxicity frequently goes undetected in preclinical safety evaluations using animal models. Human-derived in vitro models represent a common alternative to in vivo tests to detect toxic effects during preclinical testing. Most current in vitro toxicity assays rely on the measurement of nonspecific or low sensitive endpoints, which result in poor concordance with human liver toxicity. Therefore, making more accurate predictions of the potential hepatotoxicity of new drugs remains a challenge. Metabolomics, whose aim is to globally assess all the metabolites present …