Search results for "TetR"
showing 10 items of 8965 documents
Role of laparoscopic hysterectomy in cervical and endometrial cancer: a narrative review
2022
Endometrial cancer is the most common carcinoma of the female genital organs and cervical cancer is the leading cause of cancer death in women worldwide. The aim of this review is to evaluate the role of laparoscopic hysterectomy in patients with endometrial and cervical cancer in this period, and analyze the outcome of hysterectomy in terms of survival. Moreover, we present the historical background, new techniques, the anatomical features, and surgical steps of radical hysterectomy. According to new evidence, minimally invasive surgery in patients with cervical cancer is associated with higher rates of recurrence and mortality compared to the open approach. Despite the numerous explanatio…
Randomized trial of primary debulking surgery versus neoadjuvant chemotherapy for advanced epithelial ovarian cancer (SCORPION-NCT01461850)
2020
ObjectiveTo investigate whether neoadjuvant chemotherapy followed by interval debulking surgery is superior to primary debulking surgery in terms of perioperative complications and progression-free survival, in advanced epithelial ovarian, fallopian tube or primary peritoneal cancer patients with high tumor load.MethodsPatients with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer (stage IIIC-IV) underwent laparoscopy. Patients with high tumor load assessed by a standardized laparoscopic predictive index were randomly assigned (1:1 ratio) to undergo either primary debulking surgery followed by adjuvant chemotherapy (arm A), or neoadjuvant chemotherapy followed by int…
New charge transfer salts of two organic π-donors of the tetrathiafulvalene type with the paramagnetic [Cr(NCS)6]3- anion
2003
cited By 9; International audience; The electrochemical combination of the paramagnetic anion [Cr(NCS)6]3- with the organic π-donors bis(ethylenedithio)tetrathiafulvalene (ET) and 4,5-bis(2-hydroxyethylthio) -4′,5′-ethylenedithiotetrathiafulvalene (DHET-EDTTTF) leads to two new radical cation salts, namely (ET)4 [Cr(NCS 6]·PhCN 1 and (DHET-EDTTTF)2 (NEt4)[Cr(NCS)6] 2. Both have been characterized by X-ray crystallography, magnetic and resistivity measurements. The structure of 1 consists of alternating inorganic layers generated by the anions and organic layers in which the PhCN molecules are inserted; the organic sub-lattice is built up from four different ET units, three of them with a ch…
Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells
2009
The aryl hydrocarbon receptor (AhR) mediates toxicity of a variety of environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) and dioxins. However, the underlying mechanisms and genetic programmes regulated by AhR to cause adverse effects but also to counteract poisoning are still poorly understood. Here we analysed the effects of two AhR ligands, benzo[a]pyrene (B[a]P), a DNA damaging tumour initiator and promotor and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a pure tumour promoter, on cell survival and on nucleotide excision repair (NER) gene expression. NER deals with so called "bulky" DNA adducts including those generated by enzymatically activated B[a]P. Therefore, t…
Effetti del Papillomavirus genitale sulla riproduzione umana
2009
Human papillomaviruses (HPVs) are agents of the most common sexually transmitted disease that can infect both females and males. More than 100 HPV-genotypes are known, of these, 40 genotypes infect the low genital tract. Based on their association with cervical cancer and precursor lesions, genital HPVs can also be grouped to high-risk and low-risk HPV-types. Diagnosis of HPV infection is sometime difficult because the infection is often transient and asymptomatic. High-risk HPV types are more likely to persist than are low-risk HPV types. It’s the inability of the immune system to spontaneously clear HPV that leads to development of precancerous cervical lesions. It is generally assumed th…
The effect of musical tempo on video game performance
2012
There is little research on music and audio in video games. What theory exists relies heavily upon borrowing concepts from similar fields such as film music. The empirical research conducted has been varied in scope, but small in number. This thesis explores the current state of theory and research in video game music and audio. In order to investigate if music can affect performance in a video game, an experiment was conducted. Participants were asked to play the popular video game Tetris multiple times to music of varying tempi. The performance of each participant for every game played was recorded and compared across the conditions. Although no statistically significant differences in pe…
An Extremely Rare Case of Disseminated Peritoneal Leiomyomatosis with a Pelvic Leiomyosarcoma and Omental Metastasis after Laparoscopic Morcellation:…
2022
Minimally invasive treatment of uterine fibroids usually requires a power morcellation, which could be associated with several complications. A rare sequela is disseminated peritoneal leiomyomatosis. Indeed, recurrence or metastasis in these cases could be attributed to iatrogenic or under-evaluation of primary tumors, although a subset of cases is a sporadic sample of biological progression. We present an extremely rare case of a patient who underwent laparoscopic morcellation and after 12 years developed a pelvic leiomyosarcoma with two omental metastases, disseminated peritoneal leiomyomatosis with a parasite leiomyoma with bizarre nuclei and a parasite cellular leiomyoma simultaneously.…
CCDC 294531: Experimental Crystal Structure Determination
2007
Related Article: C.J.Gomez-Garcia, E.Coronado, S.Curreli, C.Gimemez-Saiz, P.Deplano, M.L.Mercuri, L.Pilia, A.Serpe, C.Faulmann, E.Canadell|2006|Chem.Commun.||4931|doi:10.1039/b610408h
CCDC 1945945: Experimental Crystal Structure Determination
2019
Related Article: Suchithra Ashoka Sahadevan, Alexandre Abhervé, Noemi Monni, Pascale Auban-Senzier, Joan Cano, Francesc Lloret, Miguel Julve, Hengbo Cui, Reizo Kato, Enric Canadell, Maria Laura Mercuri, Narcis Avarvari|2019|Inorg.Chem.|58|15359|doi:10.1021/acs.inorgchem.9b02404
CCDC 1455868: Experimental Crystal Structure Determination
2016
Related Article: Philipp Benrath, Maximilian Kaiser, Thomas Limbach, Mihail Mondeshki and Jan Klett|2016|Angew.Chem.,Int.Ed.|55|10886|doi:10.1002/anie.201602792