Search results for "TetR"
showing 10 items of 8965 documents
Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.
2003
Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…
1,1,4,4-Tetramethylpiperazinediium dibromide
2009
A small quantity of the title compound, C8H20N22+·2Br−, was formed as a by-product in a reaction between a diamine and an alkyl bromide. The asymmetric unit contains half of a centrosymmetric dication and a bromide anion. In the crystal, weak intermolecular C—H...Br hydrogen bonds consolidate the crystal packing.
Ultrasound bioeffects in rats: quantification of cellular damage in the fetal liver after pulsed Doppler imaging
2011
Objective To determine whether pulsed Doppler examination of the ductus venosus in rat fetuses could damage exposed tissue. Methods On gestational day 18, the livers of a mean of approximately five fetuses per mother (n = 5.14, SD = 1.6), in a cohort of 35 pregnant female rats, were exposed individually to pulsed Doppler and these were considered the 'exposed group'. The remaining fetuses in each pregnant rat (n = 5.16, SD = 2.1) formed the 'control group'. We tested for 600, 300, 60, 20, 15, 10 and 3 s of exposure of the fetal ductus venosus and the damage was evaluated measuring a cell death index of apoptotic activity at 7 h post-exposure (n = 16). In addition, subgroups of mothers were …
Estrategias y líneas de acción para la concreción de un método de praxis para el desarrollo de la técnica de base del saxofón u otros instrumentos de…
2022
El estudio de diversas tendencias o estilos musicales de manera simultánea crea ambigüedad y en cierto modo controversia, tanto para estudiantes, como para profesionales y aficionados de la música, en lo que se refiere a abordar distintos estilos musicales con diferentes fundamentos musicales y con cualidades desiguales en cuanto a carácter, expresión y forma. Este trabajo es la consecuencia de un profundo estudio de investigación con el objetivo de poder determinar estrategias y líneas de acción para la concreción de un método de praxis para el desarrollo de la técnica de base en el saxofón y otros instrumentos de viento en todos los estilos. La investigación se fundamenta en la creación, …
Being active in pregnancy: Theory-based factors associated with physical activity among pregnant women.
2018
ABSTRACTAlthough regular physical activity is recommended for pregnant women, compared to pre-pregnancy, antenatal physical activity often reduces or ceases completely. Drawing from the theory of planned behavior, self-determination theory, and theory on self-control, we aimed to test an integrative model of physical activity in a sample of pregnant women. The current study was conducted in Brisbane, Australia, in 2014–2015 using a prospective-correlational design with a one-week follow-up. Participants (N = 207, Time 1; Meanage = 30.03 years, SDage = 4.49 years) completed an initial survey measuring: intrinsic motivation from the self-determination theory, social cognitive constructs from …
The role of self-esteem on fear of childbirth and birth experience
2022
Objective: Fear of childbirth (FOC), also referred to as tokophobia, can have detrimental consequences for a woman’s well-being during pregnancy and for their subjective birth experience. However, it is unknown what role self-esteem plays in the relationship between FOC and the experience of childbirth. This study investigates the relation between FOC and the birth experience, and the role of selfesteem in that relation. Methods: We studied 125 nulliparous and parous Finnish women from their third trimester of pregnancy to 4–8 weeks postpartum. Path analysis with MLR estimation was conducted using MPlus to predict the childbirth experience according to prior self-esteem and fear of childbir…
Endoluminal stent-graft relining of visceral artery bypass grafts to treat perigraft seroma.
2013
Purpose: To describe the endovascular treatment of intra-abdominal perigraft seromas associated with small-caliber expanded polytetrafluoroethylene (ePTFE) grafts. Case Reports: Two patients who underwent hybrid repair of thoracoabdominal aortic aneurysms in which renovisceral bypass grafts were implanted presented with large, symptomatic perigraft seromas. The 5- to 8-mm-diameter ePTFE bypass grafts believed to be involved in the seromas were successfully relined with self-expanding Viabahn stentgrafts in percutaneous procedures. The patients’ symptoms were relieved, and imaging follow-up (18 and 10 months, respectively) has shown near complete resorption of the seromas. Conclusion: It is …
Potential combined effects of maternal smoking and coffee intake on foetal death within the Danish National Birth Cohort
2018
Background: Several studies have linked coffee intake and smoking to foetal death, but a possible interaction between both exposures remains unknown.Methods: We studied, within the Danish National Birth Cohort, the potential interaction between smoking and coffee drinking while pregnant on the risk of foetal (early and late) death. The study included 90 086 pregnant women, with information about their smoking habit and coffee intake in early pregnancy, and several potential confounding factors. Interaction was studied by calculating both the hazard ratio (HR) in Cox's regression (linear and smoothed restricted cubic spline) and the interaction contrast ratio (ICR).Results: Women who neither…
Negatīvu interneta komentāru atkarība no komentētāja tumšās tetrādes personības iezīmēm un komentāru mērķa daļējas sociālās klātbūtnes
2017
Pētījuma mērķis – pētīt, kā sociālo klātbūtni raksturojošie faktori, tumšās tetrādes iezīmes un diskusijas tēma paredz tendenci atstāt negatīvus komentārus, un to, vai sociālās klātbūtnes faktorus ietekmē teksta modifikācija ar cilvēka fotogrāfiju vai neverbālajiem signāliem. 200 respondenti atbildēja uz komentāru un aizpildīja īso tumšās triādes skalu, sadistiskās personības novērtējumu un tiešsaistīto prātu sociālās klātbūtnes aptaujas divus faktorus. Statistiski nozīmīgā līmenī neverbālo signālu pievienošana tekstam ietekmēja uztverto emocionālo izpratni (UEI). Tendenci atstāt negatīvus komentārus statistiski nozīmīgi izlasē skaidroja psihopātija, abi sociālās klātbūtnes faktori un disku…