Search results for "Tetrad"
showing 7 items of 267 documents
Anti-inflammatory effects of zinc in PMA-treated human gingival fibroblast cells
2015
Objectives: Abnormal cellular immune response has been considered to be responsible for oral lesions in recurrent aphthous stomatitis. Zinc has been known to be an essential nutrient metal that is necessary for a broad range of biological activities including antioxidant, immune mediator, and anti-inflammatory drugs in oral mucosal disease. The objective of this study was to investigate the effects of zinc in a phorbol-12-myristate-13-acetate (PMA)-treated inflammatory model on human gingival fibroblast cells (hGFs). Study Design: Cells were pre-treated with zinc chloride, followed by PMA in hGFs. The effects were assessed on cell viability, cyclooxygenease-1,2(COX-1/2) protein expression, …
Oxygen Atom Transfer Catalysis by Dioxidomolybdenum(VI) Complexes of Pyridyl Aminophenolate Ligands
2021
A series of new cationic dioxidomolybdenum(VI) complexes [MoO2(Ln)]PF6 (2-5) with the tripodal tetradentate pyridyl aminophenolate ligands HL2-HL5 have been synthesized and characterized. Ligands HL2-HL4 carry substituents in the 4-position of the phenolate ring, viz. Cl, Br and NO2, respectively, whereas the ligand HL5, N-(2-hydroxy-3,5-di-tert-butylbenzyl)-N,N-bis(2-pyridylmethyl)amine, is a derivative of 3,5-di-tert-butylsalicylaldehyde. X-ray crystal structures of complexes 2, 3 and 5 reveal that they have a distorted octahedral geometry with the bonding parameters around the metal centres being practically similar. Stoichiometric oxygen atom transfer (OAT) properties of 5 with PPh3 wer…
CCDC 1864766: Experimental Crystal Structure Determination
2018
Related Article: Jasmin Krause, Dimitris I. Alexandropoulos, Luca M. Carrella, Eva Rentschler, Theocharis C. Stamatatos|2018|Chem.Commun.|54|12499|doi:10.1039/C8CC07722C
CCDC 1869182: Experimental Crystal Structure Determination
2018
Related Article: Jasmin Krause, Dimitris I. Alexandropoulos, Luca M. Carrella, Eva Rentschler, Theocharis C. Stamatatos|2018|Chem.Commun.|54|12499|doi:10.1039/C8CC07722C
Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.
2003
Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…
CCDC 1512900: Experimental Crystal Structure Determination
2017
Related Article: Shobhraj Haldar, Gonela Vijaykumar, Luca Carrella, Steven Batha, Ghezai T. Musie, Manindranath Bera|2017|ACS Omega|2|1535|doi:10.1021/acsomega.7b00189
CCDC 136825: Experimental Crystal Structure Determination
2001
Related Article: T.Schneppensieper, G.Liehr, R.van Eldik, J.Ensling, P.Gutlich|2000|Inorg.Chem.|39|5565|doi:10.1021/ic000108f