Search results for "Text mining"

showing 10 items of 510 documents

Mutations in theERCC2(XPD) gene associated with severe fetal ichthyosis and dysmorphic features

2016

0301 basic medicineGeneticsFetusbusiness.industryIchthyosisObstetrics and Gynecology030105 genetics & hereditymedicine.disease03 medical and health sciencesText miningMedicineERCC2businessGeneGenetics (clinical)Prenatal Diagnosis
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Modulation astrogliale de la stimulation cérébrale profonde dans la dépression

2016

0301 basic medicineGynecology03 medical and health sciencesmedicine.medical_specialty030104 developmental biology0302 clinical medicineText miningbusiness.industrymedicineGeneral Medicinebusiness030217 neurology & neurosurgeryGeneral Biochemistry Genetics and Molecular Biologymédecine/sciences
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HPV vaccine hesitancy among parents of female adolescents: a pre-post interventional study

2017

Human papillomavirus (HPV) is the most common sexually transmitted infection in female adolescents. The highest infection rate is found among individuals aged 15-24 years, and the HPV vaccine represents an opportunity to reduce the burden of cervical cancer caused by HPV types 16 and 18. The World Health Organization has defined girls aged 9e13 years as the priority target for HPV vaccination. In Italy, in accordance with international public health guidelines, HPV vaccination wasfree and actively offered to all girls during their 12th year of life (from the completion of 11 years until the age of 12 years) between 2007 and 2008, establishing a target vaccination coverage of 95% within 5 ye…

0301 basic medicineGynecologymedicine.medical_specialtybusiness.industry030106 microbiologyPublic Health Environmental and Occupational HealthGeneral MedicinePublic Health Human papillomavirus vaccination preventionSettore MED/42 - Igiene Generale E Applicata03 medical and health sciences0302 clinical medicineText miningFamily medicinemedicine030212 general & internal medicinebusiness
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mTOR inhibition in diffuse large B-cell lymphoma: new hope?

2016

0301 basic medicineLymphoma B-Cellbusiness.industryHematologymedicine.diseaseImmunohistochemistryLymphoma03 medical and health sciences030104 developmental biology0302 clinical medicineText miningmedicine.anatomical_structure030220 oncology & carcinogenesismedicineCancer researchImmunohistochemistryHumansLymphoma Large B-Cell DiffusebusinessDiffuse large B-cell lymphomaPI3K/AKT/mTOR pathwayB cellThe Lancet. Haematology
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Better together than alone: the cumulus benefits.

2018

0301 basic medicineMale030219 obstetrics & reproductive medicinebusiness.industryMEDLINEObstetrics and GynecologyBiologyBioinformaticsSpermatozoa03 medical and health sciences030104 developmental biology0302 clinical medicineText miningmedicine.anatomical_structureReproductive MedicineOvarian FolliclemedicineHumansFemaleSperm Injections IntracytoplasmicOvarian folliclebusinessFertility and sterility
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Would Kinetic Analyses of Plasma Cytomegalovirus DNA Load Help to Reach Consensus Criteria for Triggering the Initiation of Preemptive Antiviral Ther…

2016

0301 basic medicineMicrobiology (medical)business.industry030106 microbiologyAntiviral therapyConsensus criteriaBioinformaticsCytomegalovirus DNA03 medical and health sciences0302 clinical medicineInfectious DiseasesText miningMedicine030212 general & internal medicinebusinessClinical Infectious Diseases
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Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer: A Retrospective Analysis in the Neoadjuvant Setting

2021

The neutrophil to lymphocyte ratio (NLR) is a promising predictive and prognostic factor in breast cancer. We investigated its ability to predict disease-free survival (DFS) and overall survival (OS) in patients with luminal A- or luminal B-HER2-negative breast cancer who received neoadjuvant chemotherapy (NACT). Pre-treatment complete blood cell counts from 168 consecutive patients with luminal breast cancer were evaluated to assess NLR. The study population was stratified into NLRlow or NLRhigh according to a cut-off value established by receiving operator curve (ROC) analysis. Data on additional pre- and post-treatment clinical-pathological characteristics were also collected. Kaplan–Mei…

0301 basic medicineOncologyAdultmedicine.medical_specialtyMultivariate analysisNeutrophilsQH301-705.5medicine.medical_treatmentBreast NeoplasmsArticleDisease-Free Survivalpredictive/prognostic biomarkers03 medical and health sciences0302 clinical medicineText miningBreast cancerluminal breast cancerInternal medicineMedicineHumansLymphocytesNeutrophil to lymphocyte ratioBiology (General)Neoadjuvant therapyAgedRetrospective StudiesChemotherapybusiness.industryProportional hazards modelallergologyfungiLuminal breast cancer; Neoadjuvant chemotherapy; Neutrophil to lymphocyte ratio (NLR); Predictive/prognostic biomarkers; Adult; Aged; Breast Neoplasms; Disease-Free Survival; Female; Humans; Ki-67 Antigen; Lymphocytes; Middle Aged; Multivariate Analysis; Neutrophils; Prognosis; Retrospective Studies; Treatment Outcome; Neoadjuvant TherapyHistologyGeneral MedicineMiddle Agedmedicine.diseasePrognosisneutrophil to lymphocyte ratio (NLR)Neoadjuvant Therapy030104 developmental biologyKi-67 AntigenTreatment Outcome030220 oncology & carcinogenesisMultivariate AnalysisPopulation studyFemalebusinessneoadjuvant chemotherapy
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Neoadjuvant score in locally advanced rectal cancer: integrating downstaging in risk assessment and looking for new valuable end points

2018

0301 basic medicineOncologyDisease free survivalmedicine.medical_specialtyColorectal cancermedicine.medical_treatmentLocally advancedMEDLINERectumRisk AssessmentDisease-Free Survival03 medical and health sciences0302 clinical medicineText miningInternal medicineHumansMedicineNeoadjuvant therapyRectal Neoplasmsbusiness.industryRectumHematologymedicine.diseaseNeoadjuvant Therapy030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisbusinessRisk assessmentAnnals of Oncology
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Schlafen-11 (SLFN11): a step forward towards personalized medicine in small-cell lung cancer?

2018

Purpose Both temozolomide (TMZ) and poly (ADP-ribose) polymerase (PARP) inhibitors are active in small-cell lung cancer (SCLC). This phase II, randomized, double-blind study evaluated whether addition of the PARP inhibitor veliparib to TMZ improves 4-month progression-free survival (PFS). Patients and Methods A total of 104 patients with recurrent SCLC were randomly assigned 1:1 to oral veliparib or placebo 40 mg twice daily, days 1 to 7, and oral TMZ 150 to 200 mg/m

0301 basic medicineOncologyMaleLung NeoplasmsDNA Mutational AnalysisPoly (ADP-Ribose) Polymerase-1Placebos0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsPromoter Regions GeneticDNA Modification MethylasesAged 80 and overStandard treatmentNuclear ProteinsMiddle AgedNeoplastic Cells CirculatingImmunohistochemistryhumanitiesEditorialOncology030220 oncology & carcinogenesisFemaleNon small cellAdultmedicine.medical_specialtyMEDLINEAggressive disease03 medical and health sciencesText miningDouble-Blind MethodInternal medicinemedicineBiomarkers TumorTemozolomideHumansLung cancerneoplasmsAntineoplastic Agents AlkylatingAgedbusiness.industryTumor Suppressor ProteinsDNA Methylationmedicine.diseaseSmall Cell Lung Carcinomarespiratory tract diseases030104 developmental biologyDNA Repair EnzymesBenzimidazolesPersonalized medicinebusiness
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Precision medicine in the adjuvant treatment of gastric cancer

2018

0301 basic medicineOncologymedicine.medical_specialtybusiness.industrymedicine.medical_treatmentCancermedicine.diseasePrecision medicine03 medical and health sciences030104 developmental biology0302 clinical medicineText miningOncologyChemotherapy AdjuvantGastrectomyStomach Neoplasms030220 oncology & carcinogenesisInternal medicinemedicineHumansPrecision MedicinebusinessAdjuvantRetrospective StudiesThe Lancet Oncology
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