Search results for "Tf"

showing 10 items of 1652 documents

Effects on α- and β-cell function of sequentially adding empagliflozin and linagliptin to therapy in people with type 2 diabetes previously receiving…

2017

Aims The aim of the study was to investigate the effect of sequential treatment escalation with empagliflozin and linagliptin on laboratory markers of alpha- and beta cell function in patients with type 2 diabetes mellitus (T2DM) insufficiently controlled on metformin monotherapy. Methods Forty-four patients with T2DM received 25 mg empagliflozin for a duration of one month in an open-label fashion (treatment period (TP 1). Thereafter, patients were randomised to a double-blind add-on therapy with linagliptin 5 mg or placebo (TP 2) for one additional month. Alpha- and beta cell function were assessed with a standardised liquid meal test (LMT) and an intravenous (iv.) glucose challenge. Effi…

Blood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatment030209 endocrinology & metabolismLinagliptinType 2 diabetes030204 cardiovascular system & hematologyLinagliptinGlucagon03 medical and health sciences0302 clinical medicineEndocrinologyDouble-Blind MethodGlucosidesInternal medicineInsulin-Secreting CellsInternal MedicinemedicineEmpagliflozinHumansHypoglycemic AgentsInsulinBenzhydryl CompoundsProinsulinAgedbusiness.industryInsulinMiddle Agedmedicine.diseaseGlucagonPostprandial PeriodMetforminEndocrinologyPostprandialTreatment OutcomeDiabetes Mellitus Type 2Glucagon-Secreting CellsGlucose Clamp TechniqueFemalebusinessmedicine.drugProinsulinDiabetes, obesitymetabolism
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Search for Multimessenger Sources of Gravitational Waves and High-energy Neutrinos with Advanced LIGO during Its First Observing Run, ANTARES, and Ic…

2019

[EN] Astrophysical sources of gravitational waves, such as binary neutron star and black hole mergers or core-collapse supernovae, can drive relativistic outflows, giving rise to non-thermal high-energy emission. High-energy neutrinos are signatures of such outflows. The detection of gravitational waves and high-energy neutrinos from common sources could help establish the connection between the dynamics of the progenitor and the properties of the out¿ow. We searched for associated emission of gravitational waves and high-energy neutrinos from astrophysical transients with minimal assumptions using data from Advanced LIGO from its first observing run O1, and data from the ANTARES and IceCub…

Astrofísicacollapse [supernova]neutron star: binaryEVENTS GW150914Gravitació010504 meteorology & atmospheric sciencesneutrino: energy: highAstronomyRAYBinary numberbinary [neutron star]Astrophysics7. Clean energy01 natural sciencesPhysical ChemistryAtomicIceCubeneutrinoParticle and Plasma PhysicsAstronomi astrofysik och kosmologiblack holeAstronomy Astrophysics and CosmologyLIGO010303 astronomy & astrophysicsgravitational waveELECTROMAGNETIC SIGNALSQCQBSettore FIS/01PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)astro-ph.HE[PHYS]Physics [physics]Astrophysics::Instrumentation and Methods for Astrophysicsneutrinosgravitational waves; neutrinos520 Astronomie und zugeordnete Wissenschaftenddc:observatorySupernovagravitational wavesastrophysics: densityPhysical SciencesNeutrinoAstrophysics - High Energy Astrophysical Phenomenagravitational waves; neutrinos; Astronomy and Astrophysics; Space and Planetary ScienceAstronomical and Space SciencessignaturePhysical Chemistry (incl. Structural)supernova: collapseAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstronomy & AstrophysicsGravitational wavesemission [gravitational radiation]Ones gravitacionalsCoincident0103 physical sciencesGravitational Waves Neutrinos LIGO Virgo Antares IceCubeNuclearddc:530Neutrinsenergy: high [neutrino]NeutrinosSTFCAstrophysiqueAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesScience & TechnologyANTARESGravitational waveVirgoOrganic ChemistryAstronomyRCUKMolecularAstronomy and AstrophysicsAstronomieAstronomy and Astrophysic530 PhysikLIGOSciences de l'espaceBlack holemessengerNeutron starAntaresPhysics and AstronomySpace and Planetary ScienceFISICA APLICADA:Física::Astronomia i astrofísica [Àrees temàtiques de la UPC]gravitational radiation: emissiondensity [astrophysics]ddc:520[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]EMISSION
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Segmental contribution to forces in vertical jump.

1978

Performance of a vertical jump was analyzed with respect to the contribution of the different body segments to the forces acting on the whole body center of gravity. Both cinematograph and force-platform techniques were employed. The data disclosed that the take-off velocity in vertical jumps was caused by the different components as follows: knee extension 56%, plantar flexion 22%, trunk extension 10%, arm swing 10%, and head swing 2%. However, the average take-off velocity of the total performance (3.03 m/s) was only 76% from the theoretical maximum calculated from the segmental analyses. Optimal timing of the segmental performances was calculated to increase this “efficiency” to 84%. Gre…

MaleAnthropometryPhysiologyMovementPhysical ExertionPublic Health Environmental and Occupational HealthGeometryGeneral MedicineEfficiencySwingTrunkPlantar flexionBiomechanical PhenomenaVertical jumpCenter of gravityArm swingPhysiology (medical)HumansOrthopedics and Sports MedicineForce platformWhole bodyMathematicsEuropean journal of applied physiology and occupational physiology
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Metal concentrations and detoxification mechanisms in Solea solea and Solea senegalensis from NW Mediterranean fishing grounds

2013

10 pages, 5 figures, 4 tables

GillsCommon soleGillLipid peroxidationFisheriesZoologyAquatic ScienceBiologyOceanographyKidneyLipid peroxidationchemistry.chemical_compoundSeleniumMediterranean seaLactate dehydrogenaseMediterranean SeaAnimalsMetallothioneinL-Lactate DehydrogenaseSoleáMusclesLactate dehydrogenasebiology.organism_classificationPollutionchemistryBiochemistryMetalsInactivation MetabolicToxicityFlatfishesAcetylcholinesteraseMetallothioneinLipid PeroxidationBiomarkersWater Pollutants ChemicalEnvironmental Monitoring
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Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines

2021

Abstract Background Next Generation Sequencing (NGS) is the fundament of various studies, providing insights into questions from biology and medicine. Nevertheless, integrating data from different experimental backgrounds can introduce strong biases. In order to methodically investigate the magnitude of systematic errors in single nucleotide variant calls, we performed a cross-sectional observational study on a genomic cohort of 99 subjects each sequenced via (i) Illumina HiSeq X, (ii) Illumina HiSeq, and (iii) Complete Genomics and processed with the respective bioinformatic pipeline. We also repeated variant calling for the Illumina cohorts with GATK, which allowed us to investigate the e…

Aginglcsh:QH426-470lcsh:BiotechnologyLongevity610 MedizinGATK ; Next-generation sequencing (NGS) technologies ; Illumina ; Longevity ; Complete genomics ; Healthy aging ; Wellderly ; Aging ; Platform-biasesPlatform-biasesPolymorphism Single Nucleotide570 Life sciencesIlluminaNext-generation sequencing (NGS) technologieslcsh:TP248.13-248.65610 Medical sciences620 Engineering and allied operationsHumansComputational BiologyHigh-Throughput Nucleotide SequencingReproducibility of ResultsGATKGenomicsPhysik (inkl. Astronomie)620 Ingenieurwissenschaften und MaschinenbauWellderlylcsh:GeneticsCross-Sectional StudiesHealthy agingComplete genomics570 BiowissenschaftenResearch Article
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A Unified Approach to Portfolio Optimization with Linear Transaction Costs

2004

In this paper we study the continuous time optimal portfolio selection problem for an investor with a finite horizon who maximizes expected utility of terminal wealth and faces transaction costs in the capital market. It is well known that, depending on a particular structure of transaction costs, such a problem is formulated and solved within either stochastic singular control or stochastic impulse control framework. In this paper we propose a unified framework, which generalizes the contemporary approaches and is capable to deal with any problem where transaction costs are a linear/piecewise-linear function of the volume of trade. We also discuss some methods for solving numerically the p…

Structure (mathematical logic)Transaction costMathematical optimizationComputer sciencejel:C63General Mathematicsjel:C61Function (mathematics)Management Science and Operations ResearchSingular controljel:G11Merton's portfolio problemEconomicsPortfolioPortfolio optimizationportfolio choice transaction costs stochastic singular control stochastic impulse control computational methodsSoftwareExpected utility hypothesisSSRN Electronic Journal
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Integrating the Tumor Microenvironment into Cancer Therapy

2020

© 2020 by the authors.

0301 basic medicineCancer ResearchMechanotransductionReviewGut floralcsh:RC254-28203 medical and health sciences0302 clinical medicineImmune systemStromamedicineMechanotransductionStromal reprogrammingTumor microenvironmentbiologybusiness.industryMicrobiotaCancerlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseasebiology.organism_classificationPrognostic toolsMetforminMitochondria030104 developmental biologyMetabolismOncologyImmune therapyTumor progression030220 oncology & carcinogenesisCancer researchBiomarker discoverybusinessReprogrammingVitamin D3
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Populārāko e-komercijas platformu salīdzinājums un to analīze 2021.gadā

2022

Bakalaura darbā ir izpētītas un izanalizētas populārākās e-komercijas platformas – Shopify, WooCommerce un Magento. Ar reālu piemēru palīdzību lasītājam tiek dota iespēja iepazīties ar dažādām e-komercijas platformām, to iespējām un ar uzņēmumiem, kuri tās izmanto ikdienā.

E-COMMERCEE-KOMERCIJAS ANALĪZEE-KOMERCIJAS PLATFORMAEkonomika un uzņēmējdarbībaE-COMMERCE PLATFORME-KOMERCIJA
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Gratitude Questionnaire–20 Items (G20): A Cross-Cultural, Psychometric and Crowdsourcing Analysis

2020

The use in psychology of crowdsourcing platforms as a method of data collection has been increasing in popularity because of its relative ease and versatility. Our goal is to adapt the Gratitude Questionnaire–20 Items (G20) to the English language by using data collected through a crowdsourcing platform. The G20 is a comprehensive instrument that takes in consideration the different basic processes of gratitude and assesses the construct’s cognitive, evaluative, emotional, and behavioral processes. We test the psychometric properties of the English version of the G20 with a Prolific (ProA) user sample. We assess the adequacy of the G20 for the crowdsourcing population in its English version…

validitymedia_common.quotation_subjectPopulationApplied psychologypositive psychologylcsh:BF1-990050109 social psychologySample (statistics)Crowdsourcing050105 experimental psychologygratitude questionnairecross-culturalGratitudeEnglish adaptationPsychology0501 psychology and cognitive scienceseducationGeneral Psychologymedia_commonOriginal Researcheducation.field_of_studyData collectionreliabilitybusiness.industry05 social sciencesPopularityTest (assessment)lcsh:Psychologycrowdsourcing platformpsychometrybusinessConstruct (philosophy)PsychologyFrontiers in Psychology
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Global data on earthworm abundance, biomass, diversity and corresponding environmental properties

2021

Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ec…

Data DescriptorDistribuição GeográficaPlan_S-Compliant-OASoilBiomassbiodiversityDiversityEcologyBiodiversidadeQBiodiversityeliöyhteisötmaaperäeliöstöPE&RCComputer Science ApplicationsMultidisciplinary SciencesBiogeographyinternational1181 Ecology evolutionary biologyEcosystem engineersScience & Technology - Other TopicsStatistics Probability and UncertaintyInformation SystemsStatistics and ProbabilitylierotScienceInvertebradosLibrary and Information Sciences[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil studyEcology and EnvironmentEducationeliömaantiede[SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/EcosystemsMinhocaServiço ambientalBIODIVERSITY CHANGELife ScienceEcosystem servicesEarthwormsDatasetsAnimalsSpatial distributionCommunity ecologyOligochaetaLaboratorium voor NematologieEcosystem1172 Environmental sciencesbiogeographyScience & TechnologyLAND-USEBiology and Life SciencesPLATFORMBodemfysica en LandbeheerEcologíaEcossistemabiodiversiteettiSoil Physics and Land ManagementSoloBiologia do Solomaaperäeläimistö570 Life sciences; biologyeartworm ; abundance ; biomass ; diversityLaboratory of Nematology[SDE.BE]Environmental Sciences/Biodiversity and EcologyCOMMUNITIEScommunity ecology
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