Search results for "Theoretical Chemistry"

showing 10 items of 8456 documents

Synthesis and Structure Elucidation of Novel Spirooxindole Linked to Ferrocene and Triazole Systems via [3 + 2] Cycloaddition Reaction

2022

In the present work, a novel heterocyclic hybrid of a spirooxindole system was synthesized via the attachment of ferrocene and triazole motifs into an azomethine ylide by [3 + 2] cycloaddition reaction protocol. The X-ray structure of the heterocyclic hybrid (1″R,2″S,3R)-2″-(1-(3-chloro-4-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carbonyl)-5-methyl-1″-(ferrocin-2-yl)-1″,2″,5″,6″,7″,7a″-hexahydrospiro[indoline-3,3″-pyrrolizin]-2-one revealed very well the expected structure, by using different analytical tools (FTIR and NMR spectroscopy). It crystallized in the triclinic-crystal system and the P-1-space group. The unit cell p…

spirooxindole; ferrocene; triazole; azomethine ylide; [3 + 2] cycloaddition (32CA) reactiontriazoleazomethine ylideChemistry (miscellaneous)Organic ChemistryDrug DiscoveryferroceneMolecular MedicinePharmaceutical Sciencespirooxindole[3 + 2] cycloaddition (32CA) reactionPhysical and Theoretical ChemistryAnalytical ChemistryMolecules; Volume 27; Issue 13; Pages: 4095
researchProduct

Compared Binding Properties between Resveratrol and Other Polyphenols to Plasmatic Albumin: Consequences for the Health Protecting Effect of Dietary …

2014

International audience; Phytophenols are considered to have beneficial effects towards human physiology. They are food microcomponents with potent chemopreventive properties towards the most three frequent contemporary human diseases, e.g., cardiovascular alterations, cancer and neurodegenerative pathologies. Related to this, the plasmatic form and plasmatic level of plant polyphenols in the body circulation are crucial for their efficiency. Thus, determinations of the binding process of resveratrol and of common flavonoids produced by major edible plants, berries and fruits to plasma proteins are essential. The interactions between resveratrol and albumin, a major plasma protein, were comp…

structural changes[SDV]Life Sciences [q-bio]Pharmaceutical ScienceReviewResveratrolresveratrol01 natural sciencesAnalytical Chemistryquercetinchemistry.chemical_compound[ SDV.BBM.BC ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Resveratrol bindingDrug DiscoveryStilbenesBovine serum albuminComputingMilieux_MISCELLANEOUS0303 health sciencesbiologyfood and beveragesBlood proteins[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]3. Good healthBiochemistryChemistry (miscellaneous)HealthMolecular MedicinefluorescencePlants EdibleQuercetinSerum albuminlcsh:QD241-44103 medical and health scienceslcsh:Organic chemistryHumans[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Physical and Theoretical ChemistryBinding siteSerum Albumin030304 developmental biologyFlavonoidsBinding Sites010405 organic chemistryOrganic ChemistryAlbuminPolyphenols0104 chemical sciencesDietchemistryFoodbiology.proteinaffinityMolecules
researchProduct

Crystal structure and Hirshfeld surface analysis of [N(CH3)4][2,2′-Fe(1,7-closo-C2B9H11)2]

2017

Abstract This work investigates the meta -ferrabis(dicarbollide) anion that was isolated as salt of tetramethylammonium. The structure of the obtained crystal consisted of discrete [2,2′-Fe(1,7- closo -C 2 B 9 H 11 ) 2 ] − anions and disordered [N(CH 3 ) 4 ] + cations. The anion had a considerable chemical stability ensured by ionic and Van der Waals interactions. Thus, Hirshfeld surfaces and fingerprint plot were used to visualize, explore, and quantify intermolecular interactions in the crystal lattice of the title compound. This investigation proved that close contacts were dominated by H⋯H interactions.

structures: crystalsIonic bondingCrystal structure010402 general chemistrychemistry01 natural sciencesBiochemistryIonInorganic ChemistryCrystalchemistry.chemical_compoundsymbols.namesakeComputational chemistrymeta-carboraneMaterials ChemistryPhysical and Theoretical Chemistryta116x-ray crystallographyTetramethylammoniummetallabis(dicarbollide)010405 organic chemistryOrganic ChemistryIntermolecular forcex-ray technology0104 chemical sciencesCrystallographydihydrogen bondschemistrysymbolsChemical stabilityvan der Waals forceHirshfeld studyJournal of Organometallic Chemistry
researchProduct

Classical and reverse substituent effects in meta- and para-substituted nitrobenzene derivatives

2017

Electron-accepting properties of the nitro group were studied in a series of meta- and para-X-substituted nitrobenzene derivatives (X = NMe2, NH2, OH, OMe, CH3, H, F, Cl, CF3, CN, CHO, COMe, CONH2, COOH, COCl, NO2, NO). For this purpose Hammett-like approaches were applied based on quantum chemistry modeling; the B3LYP/6-311++ G(d,p) method was used. The substituent effect (SE) was characterized by the mutually interrelated descriptors: the charge of the substituent active region, cSAR(X), and substituent effect stabilization energy, SESE, as well as substituent constants, σ. Classical SE is realized by dependences of the structural parameters of the nitro group (ONO angle and NO bond lengt…

substituent effectsMolecular modelmolecular modeling010405 organic chemistryDinitrobenzeneStereochemistrySubstituentelectronic structure010402 general chemistryCondensed Matter Physics01 natural sciencesQuantum chemistry0104 chemical sciencesNitroanilineBond lengthNitrobenzenechemistry.chemical_compoundchemistrysubstituent effect stabilization energyNitroPhysical and Theoretical Chemistrycharge of the substituent active regionStructural Chemistry
researchProduct

Titanocene Selenide Sulfides Revisited: Formation, Stabilities, and NMR Spectroscopic Properties

2019

[TiCp2S5] (phase A), [TiCp2Se5] (phase F), and five solid solutions of mixed titanocene selenide sulfides [TiCp2SexS5−x] (Cp = C5H5−) with the initial Se:S ranging from 1:4 to 4:1 (phases B–E) were prepared by reduction of elemental sulfur or selenium or their mixtures by lithium triethylhydridoborate in thf followed by the treatment with titanocene dichloride [TiCp2Cl2]. Their 77Se and 13C NMR spectra were recorded from the CS2 solution. The definite assignment of the 77Se NMR spectra was based on the PBE0/def2-TZVPP calculations of the 77Se chemical shifts and is supported by 13C NMR spectra of the samples. The following complexes in varying ratios were identified in the CS2 solutions of …

sulfidit77Se-NMR spectroscopyPharmaceutical ScienceCrystal structureSulfidesorganometalliyhdisteet010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Seleniumcrystal structureschemistry.chemical_compoundChalcogenlcsh:Organic chemistrytitanocene selenide sulfidesSelenide0103 physical sciencesDrug DiscoveryOrganometallic CompoundsCarbon-13 Magnetic Resonance SpectroscopyNMR-spektroskopiaPhysical and Theoretical Chemistryta116DLPNO-CCSD(T) calculations13C-NMR spectroscopyCrystallographyMolecular Structure010304 chemical physics<sup>13</sup>C-NMR spectroscopyChemistryChemical shiftOrganic ChemistryTitanocene dichlorideCarbon-13 NMRkiteetStandard enthalpy of formation0104 chemical sciencesNMR spectra databasetitaani<sup>77</sup>Se-NMR spectroscopyChemistry (miscellaneous)Carbon DisulfideseleeniQuantum TheoryMolecular MedicinePhysical chemistryMolecules
researchProduct

1,2,6-Thiadiazine 1-Oxides: Unsaturated Three-Dimensional S,N-Heterocycles from Sulfonimidamides.

2020

Unprecedented three-dimensional 1,2,6-thiadiazine 1-oxides have been prepared by an aza-Michael-addition/cyclization/condensation reaction sequence starting from sulfonimidamides and propargyl ketones. The products have been further functionalized by standard cross-coupling reactions, selective bromination of the heterocyclic ring, and conversion into a β-hydroxy substituted derivative. A representative product was characterized by single-crystal X-ray structure analysis. peerReviewed

sulfonimidamidessingle-crystal X-raybioaktiiviset yhdisteet010405 organic chemistryStereochemistryChemistryOrganic ChemistryOxideHalogenation010402 general chemistryCondensation reaction01 natural sciencesBiochemistryCoupling reaction0104 chemical scienceschemistry.chemical_compoundPropargylPhysical and Theoretical ChemistrySequence (medicine)Organic letters
researchProduct

CO(2)-water supercritical mixtures: Test of a potential model against neutron diffraction data

2007

Abstract A neutron diffraction experiment on supercritical mixtures of water and CO 2 at two concentrations is presented. Data are analyzed within the EPSR framework and the water–water and water–CO 2 radial distribution functions are compared with those calculated by a Molecular Dynamics simulation performed by using the TIPS2 and EPM-M potential models for water and CO 2 respectively. It is found that the Molecular Dynamics simulation reproduces the overall shape of the site–site radial distribution functions, although missing a few subtle changes brought along when the CO 2 concentration is increased.

supercritical fluidChemistryNeutron diffractionAnalytical chemistryThermodynamicsRadial distributionCondensed Matter PhysicsAtomic and Molecular Physics and OpticsSupercritical fluidElectronic Optical and Magnetic MaterialsMolecular dynamicsneutron diffractionMaterials ChemistryAstrophysics::Earth and Planetary AstrophysicsPhysical and Theoretical ChemistryPhysics::Atmospheric and Oceanic PhysicsSpectroscopy
researchProduct

The Jäntti approach to adsorption with increasing gas pressure

2002

Jäntti introduced a method of calculating equilibrium adsorption from measurements where the pressure of the gas was varied in a stepwise manner. His aim was to shorten the time necessary for a given measurement. The method was applied to gas/solid systems in which simple adsorption processes occurred and where the number of adsorption sites was infinite. The present paper discusses the case where no adsorption is possible on an already occupied site (Langmuir isotherm) while the number of positions available for adsorption is considered limited. The advantages of using a gas pressure that increases linearly with time are evident for studies with this limitation. It is shown that such meas…

symbols.namesakeAdsorptionGas pressureChemistryGeneral Chemical Engineeringlcsh:QD450-801symbolsThermodynamicsLangmuir adsorption modellcsh:Physical and theoretical chemistrySurfaces and InterfacesGeneral ChemistryAdsorption Science & Technology
researchProduct

Improvement of Raman Spectra of SAPO-5 by Chromium(III)-Induced Luminescence Quenching

1995

symbols.namesakeChromiumQuenching (fluorescence)chemistryGeneral EngineeringAnalytical chemistrysymbolschemistry.chemical_elementPhysical and Theoretical ChemistryPhotochemistryLuminescenceRaman spectroscopyThe Journal of Physical Chemistry
researchProduct

Impulsive excitation of high vibrational states in I2–Xe complex on the electronic ground state

2010

Abstract High vibrational states, up to ν  = 22, are excited and investigated on the ground electronic state of a 1:1 I 2 –Xe complex isolated in solid Kr using femtosecond CARS technique and spontaneous resonant Raman measurements. The results show that this system is a promising candidate for investigations of coherent control of bimolecular reactions by using vibrational wavepackets on the ground electronic state.

symbols.namesakeCoherent controlChemistryExcited stateFemtosecondsymbolsGeneral Physics and AstronomyCoherent anti-Stokes Raman spectroscopyPhysical and Theoretical ChemistryAtomic physicsGround stateRaman spectroscopyExcitationChemical Physics Letters
researchProduct