Search results for "Thiomersal"

showing 2 items of 2 documents

Piroxicam-induced photosensitivity and contact sensitivity to thiosalicylic acid

1990

A photocontact dermatitis developed in three patients after the application of gel containing 0.5% piroxicam. Patch tests were positive to thiomersal and thiosalicylic acid. Photopatch tests with piroxicam at several concentrations were positive in the three patients but negative in 62 normal volunteer subjects. Patch tests performed on 14 patients with proved systemic photosensitivity to piroxicam were positive for thiomersal and thiosalicylic acid. Nine of 12 patients previously sensitized to thiosalicylic acid and with no history of exposure to piroxicam showed positive photopatch test reactions to this chemical. These results support a relation between piroxicam-induced photosensitivity…

AdultMaleThiosalicylic acidmedicine.medical_specialtyDermatologyPiroxicamDermatitis ContactBenzoateschemistry.chemical_compoundPiroxicamPhotosensitivityMedicineHumansPhotosensitivity DisordersSulfhydryl CompoundsVolunteerbusiness.industryThimerosalPhotosensitivity reactionsPhotocontact DermatitisMiddle AgedPatch TestsContact sensitivityDermatologychemistryFemaleThiomersalbusinessGelsmedicine.drug
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Neuropsychological performance 10 years after immunization in infancy with thimerosal-containing vaccines

2009

OBJECTIVE. Thimerosal, a mercury compound used as a preservative in vaccines administered during infancy, has been suspected to affect neuropsychological development. We compared the neuropsychological performance, 10 years after vaccination, of 2 groups of children exposed randomly to different amounts of thimerosal through immunization. METHODS. Children who were enrolled in an efficacy trial of pertussis vaccines in 1992–1993 were contacted in 2003. Two groups of children were identified, according to thimerosal content in vaccines assigned randomly in the first year of life (cumulative ethylmercury intake of 62.5 or 137.5 μg), and were compared with respect to neuropsychological outcome…

MalePediatricsmedicine.medical_specialtyTime FactorsEthylmercury compoundTime FactorDevelopmental DisabilitiesDevelopmental DisabilitieControlled trialRandomizedNeuropsychological Testslaw.inventionchemistry.chemical_compoundEthylmercurySettore MED/38 - Pediatria Generale E SpecialisticaRandomized controlled triallawHumansMedicineNeuropsychological assessmentChildVaccinesmedicine.diagnostic_testSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryThimerosalPreservatives PharmaceuticalInfantThimerosalNeuropsychological testExecutive functionsBoston Naming TestchemistryPediatrics Perinatology and Child HealthImmunizationFemaleNeuropsychological TestThiomersalbusinessVaccineHuman
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