Search results for "Thoma"

Autofluorescence Imaging of the Skin Is an Objective Non-Invasive Technique for Diagnosing Pseudoxanthoma Elasticum

2021

Pseudoxanthoma elasticum (PXE) is a rare multisystemic autosomal recessive connective tissue disease. In most cases, skin manifestations of PXE are the first to develop, followed later by severe ocular and cardiovascular complications. In our present study, in addition to dermoscopy, we introduced novel techniques, autofluorescence (AF) and diffuse reflectance (DR) imaging for the assessment of affected skin sites of five PXE patients. PXE-affected skin areas in most skin sites showed a previously observed pattern upon dermoscopic examination. With the novel imaging, PXE-affected skin lesions displayed high AF intensity. During our measurements, significantly higher mean, minimum and maximu…

Centrifugal necrotic keratoacanthoma

2007

Centrifugal necrotic keratoacanthoma is a quite rare variant of keratoacanthoma, with a locally aggressive behavior and no tendency to spontaneous involution. We report a typical case of the nasal-orbital region. Based on its clinical, histological and behavioral picture, centrifugal necrotic keratoacanthoma appears as variant of giant keratoacanthoma and can be regarded as an intermediate form in a spectrum where keratoacanthoma and overt squamous cell carcinoma represent the most benign and the most malignant end, respectively, as also highlighted by analogies between the two lesions recently reported in the field of molecular biology.

Pathogenesis and clinicohistopathological caractheristics of melanoacanthoma: A systematic review.

2015

Introduction: The melanoacanthoma is a rare benign pigmented tumor, characterized by a fast radial growth and clinical behavior similar to melanoma. Color changes in oral mucosa and dermis are consequence of increased melanocyte activity as response to an irritant factor. There is a vast phenotypic variety. It is difficult to distinguish between a benign pigmented lesion and a melanoma at its early stage. Due to its clinical relevance is crucial to diagnose possible malignancy of the lesions. Objectives: The aim of this article is to conduct a systematic review of all published articles, as well as update and evaluate etiologic factors and clinicopathological features. Material and Methods:…

Nonepithelial skin tumors with multinucleated giant cells

2013

Recognition of the different types of multinucleated giant cells in neoplastic and pseudotumoral lesions of the skin may be helpful in the differential diagnosis of these tumors. In this review, we will analyze the different types of multinucleated giant cells that can be found in nonepithelial cutaneous tumors and, more importantly, the clinicopathological context in which they are found. Touton giant cells are typically present in juvenile xanthogranuloma, necrobiotic xanthogranuloma, and some subtypes of xanthomas. Giant cells with a ground glass appearance are typically present in the solitary reticulohistiocytoma and multicentric reticulohistiocytosis. Osteoclast-like cells are found i…

Postsurgical Paracicatricial Cutaneous Satellitosis of Giant Cell Tumour of the Tendon Sheath, Localized Type

2011

Tenosynovial giant cell tumour (localized type) is a tumour of tendon sheaths and interphalangeal joints, affecting the digits and arising from the synovium. It is characterized by a proliferation of mononuclear cells and osteoclast-like polykaryocytes. Its propagation to the skin is an exceptional event, which can take place either in localized form in the fingertips (localized type) or in the rare diffuse form called giant cell tumour of the tendon sheath (diffuse type). We report here a case of giant cell tumour with cutaneous satellites, which appeared close to and around the surgical scar following the excision of the primary lesion, in a 9-year-old boy. In the cutaneous satellites, a …

089 Autofluorescence imaging for non-invasive visualization and quantification of skin lesions of patients with pseudoxanthoma elasticum

2021

Wer ist wer im Leben von Thomas Mann? : ein Personenlexikon / Heinz J. Armbrust ; Gert Heine. - Frankfurt am Main : Klostermann, 2008. - 345 S.

2008

Problematiche di un "Who is who nella vita di Thomas Mann?" e proposte

Orbital-free energy functional for electrons in two dimensions

2009

We derive a non-empirical, orbital-free density functional for the total energy of interacting electrons in two dimensions. The functional consists of a local formula for the interaction energy, where we follow the lines introduced by Parr for three-dimensional systems [R. G. Parr, J. Phys. Chem. 92, 3060 (1988)], and the Thomas-Fermi approximation for the kinetic energy. The freedom from orbitals and from the Hartree integral makes the proposed approximation numerically highly efficient. The total energies obtained for confined two-dimensional systems are in a good agreement with the standard local-density approximation within density-functional theory, and considerably more accurate than …

Comment on “Critique of the foundations of time-dependent density-functional theory”

2008

A recent paper [J. Schirmer and A. Dreuw, Phys. Rev A. 75, 022513 (2007)] challenges exact time-dependent density-functional theory (TDDFT) on several grounds. We explain why these criticisms are either irrelevant or incorrect, and that TDDFT is both formally exact and predictive.

Thomas S. Szasz, precursor de la psiquiatría crítica

2015

Thomas S. Szasz (1920-2012), profesor de psiquiatría de la State University of New York en Siracusa (EE. UU.), fue el mayor crítico del cientificismo y de las prácticas coercitivas de la psiquiatría. Con treinta y cinco libros publicados y centenares de artículos, no ha existido otro autor más prolífico en su campo. Fue un intelectual de primer orden que realizó uno de los más lúcidos análisis conceptuales y epistemológicos de la psiquiatría. Este le sirvió de base para sostener su crítica abierta a los abusos de poder de la psiquiatría (encierros involuntarios, tratamientos no consentidos, etc.). Su libro de 1961 El mito de la enfermedad mental es un clásico. En él Szasz sostuvo, contra el…