Search results for "Thoracic Surgical Procedures"

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Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protoc…

2019

Background: Postoperative pulmonary complications (PPC) may result in longer duration of in-hospital stay and even mortality. Both thoracic surgery and intraoperative mechanical ventilation settings add considerably to the risk of PPC. It is unclear if one-lung ventilation (OLV) for thoracic surgery with a strategy of intraoperative high positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM) reduces PPC, compared to low PEEP without RM. Methods: PROTHOR is an international, multicenter, randomized, controlled, assessor-blinded, two-arm trial initiated by investigators of the PROtective VEntilation NETwork. In total, 2378 patients will be randomly assigned to one of two diffe…

one-lung ventilationIntraoperative ComplicationMedicine (miscellaneous)Thoracic Surgical Procedurerecruitment maneuverOrvostudományokrespiratory systemThoracic Surgical ProceduresKlinikai orvostudományokthoracic surgeryrespiratory tract diseasesPositive-Pressure RespirationMechanical ventilation; one-lung ventilation; positive end-expiratory pressure; postoperative pulmonary complication; recruitment maneuver; thoracic surgery; Humans; Intraoperative Complications; One-Lung Ventilation; Positive-Pressure Respiration; Research Design; Sample Size; Thoracic Surgical Procedures; Randomized Controlled Trials as TopicMechanical ventilationResearch DesignSample SizeHumansPharmacology (medical)postoperative pulmonary complicationIntraoperative ComplicationsMechanical ventilation; one-lung ventilation; positive end-expiratory pressure; postoperative pulmonary complication; recruitment maneuver; thoracic surgery; Medicine (miscellaneous); Pharmacology (medical)Humanpositive end-expiratory pressureRandomized Controlled Trials as Topic
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