Search results for "Thrombomodulin"

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Interaction of endothelial cells and neutrophilsin vitro: kinetics of thrombomodulin, intercellular adhesion molecule-1 (ICAM-1), E-selectin, and vas…

1999

SUMMARYRecently markers of endothelial cell activation or injury gained increasing interest as serological parameters of disease activation in vasculitides. Among these, soluble serum thrombomodulin, ICAM-1, VCAM-1 and E-selectin are of particular interest. However, only thrombomodulin showed the expected close correlation. The objective of this study was to investigate in vitro the kinetics of these endothelial cell receptors after interaction of unstimulated or cytokine-activated polymorphonuclear neutrophils (PMN) and endothelial cells in order to find evidence explaining these different clinical findings. Over the time period of up to 48 h of incubation the kinetics of thrombomodulin, I…

VasculitisNeutrophilsThrombomodulinImmunologyIntercellular Adhesion Molecule-1Vascular Cell Adhesion Molecule-1BiologyThrombomodulinAutoimmune Diseaseschemistry.chemical_compoundCell–cell interactionE-selectinHumansImmunology and AllergyVascular DiseasesVCAM-1ICAM-1Cell adhesion moleculeIntercellular Adhesion Molecule-1Coculture TechniquesEndothelial stem cellKineticsSolubilitychemistryImmunologycardiovascular systembiology.proteinEndothelium VascularE-SelectinBiomarkersClinical and Experimental Immunology

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