Search results for "Time factor"

showing 10 items of 3219 documents

Urinary metabolites of histamine and leukotrienes before and after placebo-controlled challenge with ASA and food additives in chronic urticaria pati…

2002

Background: The recovery of mediator metabolites from urine has the potential to provide a rapid, safe, and easily available index of release of mediators. We aimed to determine urinary metabolites of both histamine and leukotrienes (LTs) in patients affected by chronic urticaria (CU). Methods: Twenty patients with CU were studied. They were selected on the basis of double-blind placebo-controlled challenge (DBPC) with acetyl salicylic acid (ASA) and food additives. Ten patients (group B) were negative to both challenges. Ten patients (group C) presented urticaria and/or the appearance of angioedema during or 24 h after challenge, with reactions to ASA (five patients) or food additives (fiv…

AdultMalemedicine.medical_specialtyTime FactorsUrticariaUrinary systemImmunologyMethylhistamineProvocation testAdministration OralUrinePlaceboGastroenterologyBronchoconstrictor AgentsDrug HypersensitivityExcretionchemistry.chemical_compoundDouble-Blind MethodSodium BenzoateInternal medicineSodium GlutamatemedicineHumansSulfitesImmunology and AllergyCyclooxygenase InhibitorsTartrazineLeukotriene E4CreatinineAspirinDose-Response Relationship DrugAngioedemabusiness.industryMethylhistaminesMiddle AgedEndocrinologyItalychemistryChronic DiseaseFemaleFood AdditivesControlled Clinical Trials as Topicmedicine.symptombusinessBiomarkersAllergy
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Iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis and the quality of life: a new therapeutic protocol

2006

Objectives: to evaluate the clinical efficacy and the effects on the quality of life of Iloprost, a prostacyclin analogue, used, according to a new protocol, in patients with Raynaud’s phenomenon secondary to Systemic Sclerosis. Methods: in this randomized study we treated 30 patients with Iloprost given by intravenous infusion, at progressively increasing doses (starting from 0.5 ng/Kg/min up 2 ng/Kg/min) over a period of 6 hours a day for ten days in two consecutive weeks, with repeated cycles at regular intervals of three months for 18 months. The results were compared with those obtained in 30 other patients, who had received the same drug but with different posologic schemes. Results: …

AdultMalemedicine.medical_specialtyTime FactorsVasodilator AgentsSeverity of Illness IndexDrug Administration ScheduleSclerodermalaw.inventionRheumatologyRandomized controlled trialQuality of lifelawSeverity of illnessmedicineHumansPharmacology (medical)IloprostProspective StudiesDosingInfusions IntravenousProspective cohort studySystemic Sclerosis Raynaud's phenomenon Iloprost Quality of lifeScleroderma SystemicDose-Response Relationship DrugVascular diseasebusiness.industryRaynaud DiseaseMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeAnesthesiaQuality of LifeFemalebusinessIloprostmedicine.drugRheumatology
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Evolution of electromyographic signal, running economy, and perceived exertion during different prolonged exercises

2000

International audience; The purpose of this study was to compare the electromyographic (EMG) signal of the vastus lateralis muscle obtained during a run section of a triathlon and at the end of a prolonged run performed at the same running velocity. Seven subjects were studied on three occasions: a 2 h 15 min triathlon (30 min swimming, 60 min cycling, and 45 min treadmill running at 75% of the maximal aerobic speed), a 2 h 15 min run, where the last 45 min (Prolonged Run, PR) were run at the same speed as the Triathlon Run (TR) on a motorized treadmill, and a 45 min Isolated Run (IR) performed at the same TR and PR velocity. The three experimental trials were randomised. Oxygen uptake (VO …

AdultMalemedicine.medical_specialtyTime FactorsVastus lateralis muscleprolonged run[SHS.SPORT.PS]Humanities and Social Sciences/Sport/Sport physiologyPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseElectromyography[SHS.SPORT.DS]Humanities and Social Sciences/Sport/SportsTriathlonRunning03 medical and health sciences0302 clinical medicineInternal medicineHeart ratemedicineHumansOrthopedics and Sports MedicineTreadmillMuscle SkeletalFatigueRating of perceived exertionMuscle fatiguemedicine.diagnostic_testElectromyographybusiness.industrymyoelectric power spectrum030229 sport sciencesoxygen uptakePhysical EndurancePhysical therapyCardiologyRunning economyPerceptionmuscle fatiguebusiness030217 neurology & neurosurgeryMuscle Contraction
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Evidence of neuromuscular fatigue after prolonged cycling exercise

2000

International audience; Purpose: The purpose of this study was to analyze the effects of prolonged cycling exercise on metabolic, neuromuscular, and biomechanical parameters. Methods: Eight well-trained male cyclists or triathletes performed a 2-h cycling exercise at a power output corresponding to 65% of their maximal aerobic power. Maximal concentric (CON; 60, 120, 240°s 1), isometric (ISO; 0°s 1), and eccentric (ECC; 120,-60°s 1) contractions, electromyographic (EMG) activity of vastus lateralis (VL) and vastus medialis (VM) muscles were recorded before and after the exercise. Neural (M-wave) and contractile (isometric muscular twitch) parameters of quadriceps muscle were also analyzed u…

AdultMalemedicine.medical_specialtyTime FactorsVastus medialis[SHS.SPORT.PS] Humanities and Social Sciences/Sport/Sport physiologyNeuromuscular Junction[SHS.SPORT.PS]Humanities and Social Sciences/Sport/Sport physiologyPhysical Therapy Sports Therapy and RehabilitationPhysical exerciseIsometric exerciseElectromyography[ SHS.SPORT ] Humanities and Social Sciences/SportNeuromuscular junctionContractilityElectrocardiographyOxygen ConsumptionPhysical medicine and rehabilitationHeart RateHumansMedicineEccentricOrthopedics and Sports MedicineTRIATHLETESPEDALING RATEM-WAVEMUSCULAR TWITCH[SHS.SPORT]Humanities and Social Sciences/Sportmedicine.diagnostic_testElectromyographybusiness.industry[ SHS.SPORT.PS ] Humanities and Social Sciences/Sport/Sport physiology[SHS.SPORT] Humanities and Social Sciences/SportMUSCULAR TORQUEBicyclingBiomechanical Phenomenamedicine.anatomical_structureMuscle FatigueRespiratory Physiological PhenomenaOXYGEN UPTAKEbusinessCyclingMuscle Contraction
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Short-Term Impact of FS-LASIK and SMILE on Dry Eye Metrics and Corneal Nerve Morphology

2020

PURPOSE To analyze the short-term (up to 1 month) clinical outcomes in patients undergoing corneal laser refractive surgery and the impact on dry eye disease (DED) metrics and corneal nerves using in vivo confocal microscopy (IVCM). METHODS The unaided distance visual acuity, corrected distance visual acuity, and spherical equivalent refraction (SEQ) were determined in 16 and 13 patients undergoing FS-LASIK and SMILE, respectively. DED metrics assessed were Ocular Surface Disease Index, Dry Eye Questionnaire 5-items (DEQ-5), tear film osmolarity, tear meniscus height, noninvasive keratograph breakup time (NIKBUT), ocular staining, and meibomian gland atrophy. An automated analysis of cornea…

AdultMalemedicine.medical_specialtyTime FactorsVisual acuitygenetic structuresCorneal nervemedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityMeibomian glandKeratomileusisRefraction OcularCornea03 medical and health sciencesNerve Fibers0302 clinical medicineAtrophyRefractive surgeryOphthalmologymedicineHumansOcular Surface Disease IndexProspective StudiesMicroscopy Confocalbusiness.industryLASIKmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryDry Eye SyndromesFemaleLasers Excimersense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesCornea
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Pain and swelling after periapical surgery related to the hemostatic agent used: anesthetic solution with vasoconstrictor or aluminum chloride.

2011

Objective: To assess pain and swelling in the first 7 days after periapical surgery and their relationship with the agent used for bleeding control. Study Design: A prospective study was conducted between October 2006 and March 2009. Patients subjected to root surgery, who completed the questionnaire and who consented to the postoperative instructions were included in the study. The subjects were divided into two groups according to the hemostatic agent used: A) gauze impregnated with anesthetic solution with vasoconstrictor; or B) aluminum chloride. The patients were administered a questionnaire, and were asked to record the severity of their pain and swelling on a plain horizontal visual …

AdultMalemedicine.medical_specialtyTime FactorsVisual analogue scaleAnalgesicChloridesEdemaMedicineAluminum ChlorideEdemaHumansVasoconstrictor AgentsProspective StudiesProspective cohort studyAluminum CompoundsGeneral DentistryAstringentsAnestheticsHemostatic AgentPain Postoperativebusiness.industryPeriapical Diseases:CIENCIAS MÉDICAS [UNESCO]SurgerySolutionsOtorhinolaryngologyHemostasisAnesthesiaAnestheticUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleSwellingmedicine.symptomOral Surgerybusinessmedicine.drugMedicina oral, patologia oral y cirugia bucal
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Effect of explosive type strength training on isometric force- and relaxation-time, electromyographic and muscle fibre characteristics of leg extenso…

1985

Eleven male subjects (20-32 years) accustomed to strength training went through progressive, high-load strength training for 24 weeks with intensities ranging variably between 70 and 120% during each month. This training was also followed by a 12-week detraining period. An increase of 26.8% (P less than 0.001) in maximal isometric strength took place during the training. The increase in strength correlated (P less than 0.05) with significant (P less than 0.05-0.01) increases in the neural activation (IEMG) of the leg extensor muscles during the most intensive training months. During the lower-intensity training, maximum IEMG decreased (P less than 0.05). Enlargements of muscle-fibre areas, …

AdultMalemedicine.medical_specialtyTime FactorsWeight LiftingPhysiologyStrength trainingMuscle RelaxationeducationNeuromuscular JunctionIsometric exerciseElectromyographyMuscle hypertrophyPhysical medicine and rehabilitationInternal medicineIsometric ContractionmedicineHumansMuscle fibreLegPhysical Education and Trainingmedicine.diagnostic_testbusiness.industryElectromyographyMusclesSkeletal muscleMuscle relaxationmedicine.anatomical_structureCardiologymedicine.symptombusinessMuscle contractionMuscle ContractionActa physiologica Scandinavica
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Protein Ingestion Prior to Strength Exercise Affects Blood Hormones and Metabolism

2005

HULMI, J. J., J. S. VOLEK, H. SELANNE, and A. A. MERO. Protein Ingestion Prior to Strength Exercise Affects Blood Hormones and Metabolism. Med. Sci. Sports Exerc., Vol. 37, No. 11, pp. 1990 -1997, 2005. Purpose: The effects of protein consumption before strength training session on blood hormones, energy metabolites, RER, and excess postexercise oxygen consumption (EPOC) were examined. Methods: Ten resistance-trained young men consumed either a 25 g of whey and caseinate proteins (PROT) or a noncaloric placebo (P) in a liquid form 30 min before a heavy strength training session (STS) in a crossover design separated by at least 7 d. STS lasted 50 min and included 5 1 RM squats, 3 10 RM squat…

AdultMalemedicine.medical_specialtyTime FactorsWeight LiftingStrength trainingmedicine.medical_treatmentPhysical Therapy Sports Therapy and RehabilitationPhysical exercisePlacebosOxygen ConsumptionInternal medicinemedicineHumansInsulinIngestionTestosteroneOrthopedics and Sports MedicinePancreatic hormoneCross-Over StudiesHuman Growth HormoneChemistryInsulinFatty AcidsVenous bloodMilk ProteinsCrossover studyWhey ProteinsEndocrinologyArea Under CurveDietary ProteinsOxidation-ReductionHormoneMedicine & Science in Sports & Exercise
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Influence of somatosensory input on motor function in patients with chronic stroke.

2004

In healthy volunteers, reduction of somatosensory input from one hand leads to rapid performance improvements in the other hand. Thus, it is possible that reduction of somatosensory input from the healthy hand can influence motor function in the paretic hand of chronic stroke patients with unilateral hand weakness. To test this hypothesis, we had 13 chronic stroke patients perform motor tasks with the paretic hand and arm during cutaneous anesthesia of the healthy hand and healthy foot in separate sessions. Performance of a finger tapping task, but not a wrist flexion task, improved significantly with anesthesia of the hand, but not the foot. This effect progressed with the duration of anes…

AdultMalemedicine.medical_specialtyTime FactorsWristMotor ActivitySomatosensory systemFunctional LateralityCentral nervous system diseaseFingersPhysical medicine and rehabilitationmedicineReaction TimeHumansIn patientAnesthesiaChronic strokeStrokeAgedPain MeasurementAged 80 and overAnalysis of VarianceHand Strengthbusiness.industryFootSomatosensory CortexMiddle AgedWristmedicine.diseaseStrokemedicine.anatomical_structureNeurologyFinger tappingPhysical therapyFemaleNeurology (clinical)Analysis of varianceNeural Networks ComputerbusinessPsychomotor PerformanceAnnals of neurology
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Lower lip squamous cell carcinoma in patients with photosensitive disorders : analysis of cases treated at the Brazilian National Cancer Institute (I…

2017

Background Lower lip squamous cell carcinoma (LLSCC) is a common malignancy of the head and neck, being mainly a consequence of a chronic exposure to ultraviolet (UV) light solar radiation. Here, we evaluated the clinicopathological profile of patients with photosensitive disorders (xeroderma pigmentosum, lupus erythematosus and albinism) that developed LLSCC. Material and Methods Data from patients who had a diagnosed LLSCC with a prior xeroderma pigmentosum, lupus erythematosus or albinism diagnosis that were treated at INCA from 1999 to 2012 were collected from patients’ medical records (n=16). The control group was composed of 68 patients with LLSCC without a medical history of photosen…

AdultMalemedicine.medical_specialtyTime FactorsXeroderma pigmentosumAdolescentMalignancyYoung Adult030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinemedicineCarcinomaHumansPhotosensitivity Disordersskin and connective tissue diseasesChildGeneral DentistrySurvival analysisAgedRetrospective StudiesOral Medicine and PathologyLupus erythematosusSquamous Cell Carcinoma of Head and Neckbusiness.industryResearchAcademies and InstitutesMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyPrimary tumorExact testOtorhinolaryngologyHead and Neck Neoplasms030220 oncology & carcinogenesisLip NeoplasmsUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellPopulation studyFemaleSurgerybusinessBrazil
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