Search results for "Tissue"

Radiotherapy for Graves’ ophthalmopathy

2000

The interest in the treatment of benign diseases with radiation therapy has grown particularly in the Western part of the world. In 1996, a questionnaire was sent to 1348 institutes worldwide listed in the directory of the Society for Therapeutic Radiology and Oncology asking whether the respondents considered a list of 28 most common benign disorders as being a good indication for orbital radiotherapy.1 Questions concerned the frequency of such treatments and the treatment schedules used. The prevention of keloid formation was the most widely accepted indication, followed by Graves’ ophthalmopathy. Thus, radiotherapy for this orbital disorder is generally accepted and applied worldwide.

Inwazyjny rak piersi w ektopowej tkance gruczołowej zlokalizowanej w dole pachowym. Opis przypadku

2021

Breast cancer is the most commonly diagnosed malignancy in women in Poland. Rare, unusual forms of breast cancer remain a diagnostic problem. The incidence of ectopic breast glandular tissue in the general population varies between 0.4 and 6%. The same abnormalities and diseases as in the anatomical mammary gland may develop in this tissue. Breast cancer may develop as well. We present the case of a 36-year-old woman, who went to the doctor because of a nodule in the right armpit presented for 2 years. The patient was referred to a surgeon with suspicion of an epidermal cyst. The lesion was surgically removed and in the histopathological examination, the diagnose was: invasive breast cancer…

Heterogeneous Oxygenation of Rectal Carcinomas in Humans: A Critical Parameter for Preoperative Irradiation?

1984

The surgical treatment of rectal carcinoma in humans is often combined with irradiation. However, the efficacy of this latter treatment modality is crucially influenced by the oxygenation status of the tumor tissue to be treated. Therefore, the knowledge of the O2 supply to the tumor tissue is a decisive prerequisite for the assessment of the efficiency of radiotherapy.

Expanded forehead (Fricke) flap for large defect of lateral canthal area

1993

The use of an expanded forehead (Fricke) flap to repair large full thickness defects of the lateral canthus and/or of the upper eyelid is presented. The reconstruction is performed in two stages. In the first stage, a rectangular, 25 ml tissue expander (6 cm in width and 2 cm in length) is inserted under the skin lateral to and above the eyebrow; expansion is completed in about three weeks. At the second stage, the lesion is excised, and the laterally based expanded flap is elevated. Using the expanded Fricke flap, thinner, abundant skin is obtained, and the donor site is directly closed, without grafting and without distorting the eyebrow. If there is a shortage of conjunctiva, this can be…

Combined Epidural and General Anesthesia Prevents Excessive Oxygen Consumption Postoperatively

1994

In the postoperative period patients are at risk of excessive oxygen consumption (VO2). However, patients suffering from cardiovascular disease may be unable to increase their oxygen transport capacity sufficiently and may be especially vulnerable to tissue hypoxia as part of the reaction to intraoperative stress. During the last 10 years contradictory results concerning the benefits of a combined epidural and light general anesthesia have been published. Some of the results indicate that postoperative catabolism maybe depressed and that the neuroendocrine response to stress may be inhibited by such a combined technique1,2. We studied the effect of a combined epidural and light general anes…

Enzymatic Determination in Serum of Lathyritic and Prednisone-treated Lathyritic Rats

1966

WHILE a remarkably raised serum-level of transaminases and aldolase is found in dermatomyositis, such augmentation, as a rule, is not found in cases of severe muscular involvement of scleroderma and disseminated lupus erythematosus (acutus)1–3.

Survival of patients with gastric lymphoma in Germany and in the United States

2015

Background and Aim This study aims to examine survival for gastric lymphomas and its main subtypes, mucosa-associated lymphoid tissue lymphoma (MALT), and diffuse large B-cell lymphoma (DLBCL), in Germany and in the United States. Methods Data for patients diagnosed in 1997–2010 were used from 10 population-based German cancer registries and compared to the data from the US Surveillance, Epidemiology and End Results (SEER) 13 registries database. Patients age 15–74 diagnosed with gastric lymphomas were included in the analysis. Period analysis and modeled period analysis were used to estimate 5-year and 10-year relative survival (RS) in 2002–2010 and survival trends from 2002–2004 to 2008–2…

2021

Abstract Background Standard therapy for localised, resectable high risk soft tissue sarcomas consists of wide excision and radiotherapy over several weeks. This treatment schedule is hardly feasible in geriatric and frail patients. In order not to withhold radiotherapy from these patients, hypofractionated radiotherapy with 25 Gy in 5 fractions was evaluated in a geriatric patient population. Patients and methods A retrospective analysis was performed of 18 geriatric patients with resectable high risk soft tissue sarcomas of extremities and thoracic wall. Wound healing and short term oncologic outcome were analysed. In addition, dose constraints for radiotherapy of the extremities were tra…

Obesity, Adipokines and Metabolic Syndrome in Polycystic Ovary Syndrome

2012

The complex mechanisms linking fat excess to metabolic syndrome are not well understood, but several experimental studies have shown that altered production of adipokines plays a main role in development and progression of this disorder. In particular, reduced secretion of adiponectin has a crucial role in inducing insulin resistance but also in determining the clustering of elevated triglycerides and small, dense LDL particles. Increased leptin secretion may be responsible for sympathetic nervous system overactivity and hypertension, while reduced omentin may have an important permissive role in the development of atherogenic processes. Finally, cytokines and other adipokines (resistin, vi…

Humeral Shaft Fractures

2014

Humeral shaft fractures account for approximately 7 % of all fractures in adults. They occur after direct trauma such as traffic accidents or after indirect, rotational trauma in sports accidents or falls at home. There are two peaks of incidence in the adult population: the young male and the older female. The first patient typically is the victim of high-energy trauma with multiple lesions, a more severe humeral fracture type and concomitant soft tissue damage. The latter patient suffers a solitary lesion and is the victim of a low-energy accident such as a fall from a standing or sitting position. The fracture type is then simple and there is no or minimal soft tissue damage. As pain is …