Search results for "ToF"
showing 10 items of 841 documents
Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology
2019
Recent advances in cytometry have radically altered the fate of single-cell proteomics by allowing a more accurate understanding of complex biological systems. Mass cytometry (CyTOF) provides simultaneous single-cell measurements that are crucial to understand cellular heterogeneity and identify novel cellular subsets. High-dimensional CyTOF data were traditionally analyzed by gating on bivariate dot plots, which are not only laborious given the quadratic increase of complexity with dimension but are also biased through manual gating. This review aims to discuss the impact of new analysis techniques for in-depths insights into the dynamics of immune regulation obtained from static snapshot …
Subjecte a la memòria. Autobiografia, ficció i autoficció en la narrativa d'Ignasi Mora
2013
En aquest article s’analitza com la memòria dels espais primigenis que apareixen en l’obra literària d’Ignasi Mora intervenen decisivament en la modelació dels seus personatges. Són territoris documentats que l’escriptor pretén convertir en literaris, alhora que juga amb les històries i els personatges, en una indissoluble relació entre realitat i ficció. Els llibres de Mora, tant els biogràfics com els narratius, resulten de dificultosa o gairebé impossible classificació, proses del jo al pol oposat d’un llenguatge referencialista o essencialista, on la infància clou un temps i un espai mítics. Seguint aquest fil, al final de l’article aventurem una hipòtesi: un temps i un espai clausurats…
«Els creadors de ficcions damunt l'escena: del "teatre autobiogràfic" a l'"autobiografia escènica"»
2013
Aquest article se centra en modalitats diferents de construcció de l’obra teatral que tenen com a base una relació explícita, amb major o menor grau, entre el creador i la ficció: teatre autobiogràfic, teatre autoficcional i autobiografia escènica. Veurem com aquesta relació es fa present en el procés de recepció a través de diferents mecanismes, especialment a partir de paratextos, i com permet activar pactes de lectura entre obra i receptor de tarannà divers. En concret, aquest acostament a la metaficció autobiogràfica en el teatre contemporani es desenvolupa a partir de l’anàlisi de tres obres: «Indian summer» (1987), de Rodolf Sirera, «Currículum» (1994), de Pasqual Alapont i Carles Alb…
Prenatal Risk Calculation (PRC) 3.0: An Extended DoE-Based First-Trimester Screening Algorithm Allowing For Early Blood Sampling
2015
Aim: Both previous versions of the German PRC algorithm developed by our group for routine first-trimester screening relied on the assumption that maternal blood sampling and fetal ultrasonography are performed at the same visit of a pregnant women. In this paper we present an extension of our method allowing also for constellations where this synchronization is abandoned through preponing blood sampling to dates before 11 weeks of gestation. Methods: In contrast to the directly measured concentrations of the serum parameters PAPP-A and free ß-hCG, the logarithmically transformed values could be shown to admit the construction of reference bands covering the whole range from 16 to 84 mm CRL…
A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
2017
PubMed ID: 29047407
Strategie autofinzionali in "Leggenda privata" di Michele Mari
2019
Leggenda privata (2017) is the latest in a series of autobiographical writings by Michele Mari. The novel is the factual narration of the author's childhood and adolescence, documented by family photos, but is also the narration of a fictional and fantastic situation of writing, where the reader is involved in live recording. In particular, the narrative framework is structured almost like a personal essay that engages dialogically the norms and potentials, opportunities and risks of a theory of autobiography. The purpose of this article is to explore the limits, the difficulties, indeed the impossibility of autobiographical writing in Leggenda Privata, which instead verges towards a comple…
Thermodynamic correction of particle concentrations measured by underwing probes on fast-flying aircraft
2016
Particle concentration measurements with underwing probes on aircraft are impacted by air compression upstream of the instrument body as a function of flight velocity. In particular, for fast-flying aircraft the necessity arises to account for compression of the air sample volume. Hence, a correction procedure is needed to invert measured particle number concentrations to ambient conditions that is commonly applicable to different instruments to gain comparable results. In the compression region where the detection of particles occurs (i.e. under factual measurement conditions), pressure and temperature of the air sample are increased compared to ambient (undisturbed) conditions in certain …
Lierojen parittelumenestyksen yhteys sää- ja ympäristöoloihin, yksilötiheyteen ja yksilön kokoon
2011
Yksilön kelpoisuus riippuu jälkeläistuotosta, ja parittelumenestys on yksi jälkeläistuoton avaintekijöistä. Monien eläinlajiryhmien lisääntymistä on tutkittu laajasti sekä laboratorio-oloissa että luonnossa, mutta lierojen lisääntymismenestykseen vaikuttavia tekijöitä luonnonpopulaatioissa ei vielä juurikaan tunneta. Tämän tutkimuksen tavoitteena oli selvittää, miten kahden ekologialtaan erilaisen lierolajin parittelumenestys riippuu ympäristöoloista, yksilötiheydestä ja yksilön koosta. Tutkimuksessa käytettiin tietoja lieronäytteistä, jotka oli kerätty syksyinä 2004 ja 2005 viljelymailta eri puolilta Suomea. Spermatoforien esiintymistä yksilöillä käytettiin indikaattorina näytteenottoa ede…
Litorali dell'autofinzione: spigolature lacaniane
2017
Questo articolo intende applicare gli strumenti teorici della psicoanalisi lacaniana allo studio del romanzo autofinzionale. Si tratta, per un verso, di operare una lettura del romanzo "L'étreinte" di Philippe Vilain al livello del significante; per un altro, di cogliere le implicazioni del Simbolico in vari romanzi dello scrittore omosessuale marocchino Rachid O. L'articolo intende inoltre formulare una riflessione sul valore della critica letteraria per Jacques Lacan e sul come tale critica debba concepirsi nella logica dell'oltre-Edipo. This article aims to apply the theoretical tools of Lacanian psychoanalysis to the study of the self-fictional novel. On the one hand, it is a matter of …
Caracterización de los componentes genéticos y ambientales implicados en el envejecimiento de las levaduras vínicas
2012
La mayor parte de la fermentación vínica discurre cuando las células de la levadura Saccharomyces cerevisiae han dejado de dividirse. Así pues, la viabilidad en fase estacionaria, llamada longevidad cronológica (LC), es esencial para que la vinificación se lleve a buen término. En este trabajo de tesis doctoral, se han caracterizado diversos componentes ambientales y genéticos que influyen en la longevidad cronológica de las levaduras vínicas. En cuanto a los componentes ambientales, el incremento de la acidez y la temperatura del medio promueven el envejecimiento. Los polifenoles resveratrol y quercetina y los compuestos de dos carbonos que se producen durante la fermentación, afectan de m…