Search results for "Tomography"
showing 10 items of 2332 documents
Gout misdiagnosis due to dual-energy computed tomography artefact
2018
Positron Emission Tomography Imaging of Neurotensin Receptor-Positive Tumors with 68 Ga-Labeled Antagonists: The Chelate Makes the Difference Again
2021
Neurotensin receptor 1 (NTS1) is involved in the development and progression of numerous cancers, which makes it an interesting target for the development of diagnostic and therapeutic agents. A small molecule NTS1 antagonist, named [177Lu]Lu-IPN01087, is currently evaluated in phase I/II clinical trials for the targeted therapy of neurotensin receptor-positive cancers. In this study, we synthesized seven compounds based on the structure of NTS1 antagonists, bearing different chelating agents, and radiolabeled them with gallium-68 for PET imaging. These compounds were evaluated in vitro and in vivo in mice bearing a HT-29 xenograft. The compound [68Ga]Ga-bisNODAGA-16 showed a promising biod…
CT-Determined Maximum Pulmonary Artery to Ascending Aorta Diameter Ratio in Nonsevere COVID-19 Patients
2021
Design and implementation of PET detectors based on monolithic crystals and SiPMs
2018
Esta tesis doctoral se centra tanto en el diseño como en la validación experimental de detectores de rayos gamma para escáneres de tomografía por emisión de positrones (PET, del inglés Positron Emission Tomography). El objetivo principal de esta tesis es el diseño de innovadores bloques detectores PET de alto rendimiento. La técnica PET constituye una de las principales herramientas diagnósticas en medicina nuclear, que es una especialidad médica que utiliza sustancias radiactivas con fines diagnósticos y terapéuticos. Esta técnica de imagen médica permite visualizar procesos fisiológicos y bioquímicos del cuerpo humano in vivo, mediante la administración del elemento radiotrazador. Los rad…
Non-invasive Geophysical Surveys in Search of the Roman Temple of Augustus Under the Cathedral of Tarragona (Catalonia, Spain): A Case Study
2018
An integrated geophysical survey has been conducted at the Tarragona’s Cathedral (Catalonia, NE Spain) with the aim to confirm the potential occurrence of archaeological remains of the Roman Temple dedicated to the Emperor Augustus. Many hypotheses have been proposed about its possible location, the last ones regarding the inner part of the Cathedral, which is one of the most renowned temples of Spain (twelfth century) evolving from Romanesque to Gothic styles. A geophysical project including electrical resistivity tomography (ERT) and ground probing radar (GPR) was planned over 1 year considering the administrative and logistic difficulties of such a project inside a cathedral of religious…
Integrated geophysical surveys in the tarragona cathedral
2009
An integrated geophysical survey has been conducted at the Tarragona’s Cathedral (Catalonia, NE Spain) with the aim to detect the existence of archaeological remains of the Roman’s temple devoted to August. Many hypotheses have been proposed about its possible location, the last ones regarding the inner part of the Cathedral, which is one of the most famous temple of Spain (12th century) evolving from Romanesque to Gothic styles. A project including electrical resistivity tomography (ERT), ground probing radar (GPR) and frequency domain electromagnetics (FDEM) has been planned over one year and conducted during a week of intensive field survey. From all the methods applied, both ERT and GPR…
The New "Maximum Yield Grid" (MYG) Array in Full 3D Resistivity Tomography
2008
Over the past few years geoelectrical prospecting has experienced many innovations, ranging from instrumental refinements to improvement of data interpretation. The consequence of this has been a strong increase in the method s resolution power and, therefore, its field of application has broadened. Nevertheless, the diffusion of 3D surveys in electrical resistivity tomography has been very much limited by the long acquisition time required by this kind of investigation, as compared to 2D ERT or other geophysical exploration methods like GPR. However, 3D ERT has a great advantage in terms of resolution power, that is very important in many applications, such as archeological or cultural her…
INVERSION TESTS ON ULTRASONIC TOMOGRAPHY DATA
2010
3D Ultrasonic Tomography for non-destructive test and for diagnostic study works of art is a rather established methodology. This method allow us to locate, within the volume of work of art, areas of structural non homogeneities, areas of decay, fracture or damaged. This work wants to present some tests carried out to optimize these parameters in order to obtain a better anomaly image resolution for the case history presented. The optimization of these parameters allows locating structural non homogeneity areas, fractures or damages, within the volume, according to shape and type of the investigated anomalies.
From Feynman–Kac formulae to numerical stochastic homogenization in electrical impedance tomography
2016
In this paper, we use the theory of symmetric Dirichlet forms to derive Feynman–Kac formulae for the forward problem of electrical impedance tomography with possibly anisotropic, merely measurable conductivities corresponding to different electrode models on bounded Lipschitz domains. Subsequently, we employ these Feynman–Kac formulae to rigorously justify stochastic homogenization in the case of a stochastic boundary value problem arising from an inverse anomaly detection problem. Motivated by this theoretical result, we prove an estimate for the speed of convergence of the projected mean-square displacement of the underlying process which may serve as the theoretical foundation for the de…
Study of a High-Resolution PET System Using a Silicon Detector Probe
2015
253 páginas. Tesis Doctoral del Departamento de Física Atómica, Molecular y Nuclear de la Universidad de Valencia y del Instituto de Física Corpuscular (IFIC).