Search results for "Topi"

Convergence-based Analysis of Robustness to Delay in Anti-windup Loop of Aircraft Autopilot∗∗This work was supported by Russian Scientific Foundation…

2015

Abstract The windup phenomenon is interpreted as a consequence of the convergent property absence for system with a saturation. This makes it possible to use the frequency-domain criterion for analysis of anti-windup augmentation in the case of stable and marginally stable plants. Based on this approach, robustness of the systems with respect to time delay in the anti-windup loop is examined and the approach for an optimal choice of the static anti-windup gain is proposed. An application of the convergence-based anti-windup control strategy to aircraft flight control for the case of time-delay in the anti-windup loop is described and studied by simulations.

Co-Citation Analysis of Articles Published in Substance Abuse Journals: Intellectual Structure and Research Fields (2001-2012).

2016

The purpose of this study is to introduce a new methodology in the field of substance abuse, namely, co-citation analysis, which uses the bibliographic references of publications to establish the main thematic areas being researched and to identify the seminal documents that have contributed to establishing the intellectual foundation of the discipline at the present time.We identified all bibliographic references that were cited in documents published in the substance abuse journals included in the Journal Citation Reports in the 2001-2012 period, generating a co-citation matrix. This matrix was used to perform a co-citation network analysis.The co-citation network analysis led to the iden…

Mid-gastrointestinal bleeding: capsule endoscopy and push-and-pull enteroscopy give rise to a new medical term.

2006

Uso de indicadores bibliométricos para el análisis de temas emergentes y su evolución: spin-offs como caso de estudio

2018

[ES] Las spin-offs constituyen una de las áreas de investigación más atractivas, ya que están asociadas con fenómenos como el emprendimiento, la innovación y la transferencia del conocimiento. El presente estudio muestra que la selección y el uso de indicadores bibliométricos permite identificar y caracterizar el desarrollo y la difusión de temas de investigación emergentes como el analizado. Los principales aspectos observados en relación con el desarrollo de la investigación sobre las spin-offs son que se produce un auge en el número de publicaciones después de un largo período de latencia y la marcada naturaleza multidisciplinar del área. El presente enfoque ha analizado la evolución de …

Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection

2012

The mechanisms resulting in progressive immune dysfunction during the chronic phase of HIV infection are not fully understood. We have previously shown that arginase, an enzyme with potent immunosuppressive properties, is increased in HIV seropositive (HIV+) patients with low CD4(+) T cell counts. Here we show that the cells expressing arginase in peripheral blood mononuclear cells of HIV+ patients are low-density granulocytes (LDGs) and that whereas these cells have a similar morphology to normal-density granulocyte, they are phenotypically different. Importantly, our results reveal that increased frequencies of LDGs correlate with disease severity in HIV+ patients.

Evaluating the citywide Edinburgh 20mph speed limit intervention effects on traffic speed and volume: A pre-post observational evaluation.

2021

Objectives Traffic speed is important to public health as it is a major contributory factor to collision risk and casualty severity. 20mph (32km/h) speed limit interventions are an increasingly common approach to address this transport and health challenge, but a more developed evidence base is needed to understand their effects. This study describes the changes in traffic speed and traffic volume in the City of Edinburgh, pre- and 12 months post-implementation of phased city-wide 20mph speed limits from 2016–2018. Methods The City of Edinburgh Council collected speed and volume data across one full week (24 hours a day) pre- and post-20mph speed limits for 66 streets. The pre- and post-sp…

Psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features-A systematic review of randomized clinical trials …

2021

Objectives To review the effectiveness of psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features. Methods We included randomized clinical trials on psychological therapies for adolescents with BPD and BPD features. Data were extracted and assessed for quality according to Cochrane guidelines, and summarized as mean difference (MD) with 95% confidence intervals (CI) for continuous data and as Odds ratios (OR) with 95% CI for dichotomous data. Risk of bias was assessed using Cochrane’s risk of bias tool for each domain. When possible, we pooled trials into meta-analyses, and used Trial Sequential Analysis (TSA) to control for random errors. Quality…

Recommendations for a nomenclature system for reporting methylation aberrations in imprinted domains

2018

The analysis of DNA methylation has become routine in the pipeline for diagnosis of imprinting disorders, with many publications reporting aberrant methylation associated with imprinted differentially methylated regions (DMRs). However, comparisons between these studies are routinely hampered by the lack of consistency in reporting sites of methylation evaluated. To avoid confusion surrounding nomenclature, special care is needed to communicate results accurately, especially between scientists and other health care professionals. Within the European Network for Human Congenital Imprinting Disorders we have discussed these issues and designed a nomenclature for naming imprinted DMRs as well …

Metabolic and Vascular Effect of the Mediterranean Diet

2019

Several studies indicated how dietary patterns that were obtained from nutritional cluster analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a background pathogenetic mechanism linking metabolic risk factors to increased risk of chronic degenerative diseases. A Mediterranean diet (MeDi) style has been reported as associated with a lower degree of inflammation biomarkers and with a protective role on cardiovascular and cerebrovascular events. There is heterogeneity in defining the MedDiet, and it can, owing to its complexity, be considered as an exposome with thousands of nutrients and phytochemicals. Recently, it has been reported a novel positive ass…

Gli spazi del benessere come nuove forme dell’eterotopia

2022

Il contributo in volume analizza il tema del benessere oggi, il quale ha definito le condizioni per lo sviluppo di un mercato, e suo relativo indotto economico, per mezzo della costruzione di nuove architetture dedicate alla cura del proprio corpo: terme, S.P.A., beauty farm, palestre. Spesso molte altre strutture di tipo ricettivo, ad esempio: hotel, alberghi, residenze turistico alberghiere, residenze d’epoca, si sono trasformate in delle vere e proprie macchine architettoniche, con un alto grado di complessità funzionale, per accogliere spazi con differenti programmi funzionali dedicati alla salute dei propri clienti. Architetture dai contorni esotici che rimandano spesso a culture appar…