Search results for "Topi"

Geochemical insight into differences in the physical structures and dynamics of two adjacent maar lakes at Mt. Vulture volcano (southern Italy)

2013

[1] We report on the first geochemical investigation of the Monticchio maar lakes (Mt. Vulture volcano, southern Italy) covering an annual cycle that aimed at understanding the characteristic features of the physical structures and dynamics of the two lakes. We provide the first detailed description of the lakes based on high-resolution conductivity-temperature-depth (CTD) profiles, chemical and isotopic (H and O) compositions of the water, and the amounts of dissolved gases (e.g., He, Ar, CH4, and CO2). The combined data set reveals that the two lakes, which are separated by less than 200 m, exhibit different dynamics: one is a meromictic lake, where the waters are rich in biogenic and man…

Evaluation of enantioselective binding of basic drugs to plasma by ACE.

2007

The present paper deals with the evaluation of the stereoselective binding of antihistamines (brompheniramine, chlorpheniramine, hydroxyzine, orphenadrine and phenindamine), phenothiazines (promethazine and trimeprazine) and a local anesthetic (bupivacaine) to human plasma proteins. Since all of them are drugs highly bound to proteins, a methodology to determine the bound fraction of each drug enantiomer was proposed. This methodology includes the incubation of samples containing plasma and racemic drug, ultrafiltration of the mixture and the chiral separation of enantiomers in the bound drug fraction using affinity EKC (AEKC)-partial filling technique and HSA as chiral selector. The result…

Does sensitization through the skin occur?

2000

A different pattern of risk factors for atopic and non-atopic wheezing in 9-12-year-old children

2005

Few epidemiological studies have compared the risk factors of asthma or wheezing between atopic and non-atopic children. The objective of this study was to determine if there are specific risk factors for current wheezing related to atopic status in schoolchildren. Schoolchildren 9-12 yr of age from three Spanish cities (n = 2720) were subject to a cross-sectional study of asthma risk factors (by questionnaire) and atopy (by skin prick test) according to the ISAAC phase-II protocol. Risk factors for current wheezing (in the last 12 months) as reported by parents were investigated among the atopic (positive prick test to at least one allergen) and the non-atopic (negative prick test) childre…

Tumor tissue oxygenation as evaluated by computerized-po2-histography

1990

A computerized pO2 measurement system with a novel electrode motion pattern (Sigma-pO2-histography) was evaluated in vitro and in vivo. The system was found to be reliable in 0.9% saline and 10% hydroxyethylene starch solution and in fresh donor blood. Marked deviations were found in lipid and hemoglobin solutions and in fluorocarbon emulsions. Histograms obtained in rat liver, mouse muscle, and subcutis were similar to previously reported distributions. Direct comparison between Sigma-Eppendorf and self-constructed Whalen-type electrodes in hypoxic tumors gave similar results. A large series of measurements indicated that hypoxic and anoxic tissue areas were frequently found both in isogra…

The effectiveness of hypnosis for pain relief: A systematic review and meta-analysis of 85 controlled experimental trials.

2019

The current meta-analysis aimed to quantify the effectiveness of hypnosis for reducing pain and identify factors that influence efficacy. Six major databases were systematically searched for trials comparing hypnotic inductions with no-intervention control conditions on pain ratings, threshold and tolerance using experimentally-evoked pain models in healthy participants. Eighty-five eligible studies (primarily crossover trials) were identified, consisting of 3632 participants (hypnosis n = 2892, control n = 2646). Random effects meta-analysis found analgesic effects of hypnosis for all pain outcomes (g = 0.54-0.76, p’s<.001). Efficacy was strongly influenced by hypnotic suggestibility and u…

Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials

2021

AbstractDepression is a syndrome characterized by deep sadness and the inhibition of psychic functions, sometimes accompanied by neurovegetative disorders, with symptoms of anxiety almost always present. The disease produces alterations in a variety of neural networks and neurotransmission systems, along with a dysfunction of the hypothalamic-pituitary-adrenal axis, which leads to concomitant alterations in the immunological response. Generally, there is a parallel increase in proinflammatory mediators as well as oxidative and nitrosative damage caused by a reduction of antioxidant defenses. In a previous review, we compiled and examined studies of medicinal plants that had been evaluated i…

Microradiography and confocal laser scanning microscopy applied to enamel lesions formed in vivo with and without fluoride varnish treatment

1996

The aim of the present investigation was to combine 2 techniques suitable for lesion characterization: quantitative microradiography (TMR) and confocal laser scanning microscopy (CLSM) on in vivo induced lesions with and without a fluoride varnish (Duraphat(R)) treatment. Orthodontic bands were attached to premolars to be extracted for orthodontic reasons to induce enamel caries on the buccal surfaces. In the caries development part of the study, 1 tooth of each pair received at the start 1 topical application with the fluoride varnish Duraphat(R), the contralateral tooth serving as untreated control. All teeth were extracted after 4 weeks. In the caries progression part, the premolars were…

Mēslojuma ietekme uz metālu saturu un slāpekļa izotopu attiecību izmaiņām apšubekās

2017

Mēslojuma ietekme uz metālu saturu un slāpekļa izotopu attiecību izmaiņām apšubekās. Zadvinska K., zinātniskie vadītāji Mg. chem., pētniece Buša L., Dr. chem., prof. Vīksna A. Bakalaura darbs, 37 lappuses, 5 attēli, 24 tabulas, 39 literatūras avoti. Latviešu valodā. Darbā tika apkopota informācija par digestātu, notekūdeņu dūņām, pelniem un to izmantošanu kā mēslojumu. Pētīja literatūru par apšubekām, bioremediatoriem, vieglo stabilo izotopu attiecību un metālu noteikšanu ar instrumentālās analīzes metodēm, kā arī tika pētītas zinātniskās publikācijas, kurās tiek aprakstīta vieglo stabilo izotopu attiecību un metālu satura noteikšana apšubekās. Tika veikta vieglo stabilo izotopu attiecību u…

Idiopathic facial aseptic granuloma.

2014

Summary Idiopathic facial aseptic granuloma (IFAG) is a condition that is commonly encountered in clinical practice, but is rarely reported. It appears in childhood and its pathogenesis is still unknown. It has a benign course with resolution within a few months without aggressive treatment. Microbiological tests are negative and histological findings are nonspecific. It is possible that this condition is part of the spectrum of granulomatous rosacea in childhood. We present two cases in which diagnosis of IFAG was established and resolved without sequelae following topical antibiotic treatment.