Search results for "Toxic"

showing 10 items of 6968 documents

Biological responses of midge (Chironomus riparius) and lamprey (Lampetra fluviatilis) larvae in ecotoxicity assessment of PCDD/F-, PCB- and Hg-conta…

2016

We evaluated the utility of chironomid and lamprey larval responses in ecotoxicity assessment of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/F)-, polychlorinated biphenyls (PCB)- and mercury (Hg)-contaminated river sediments. Sediment samples were collected from the River Kymijoki with a known industrial pollution gradient. Sediment for the controls and lamprey larvae were obtained from an uncontaminated river nearby. Contamination levels were verified with sediment and tissue PCDD/F, PCB and Hg analyses. Behaviour of sediment-exposed chironomid and lamprey larvae were measured with Multispecies Freshwater Biomonitor© utilizing quadrupole impedance conversion technique. In additi…

sediment toxicitypolychlorinated biphenylsChironomus ripariuspolychlorinated dibenzo-p-dioxins and dibenzofuranselohopeanahkiainenkäyttäytyminenhuman activities
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Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(

2019

The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(N-alkylpyridinium)-1,4-dihydropyridine (1,4-DHP) derivatives differing in alkyl chain length and propargyl moiety/ties number and position were selected for the study of their self-assembling properties, evaluation of their cytotoxicity in vitro and toxicity on microorganisms, and the characterisation of their interaction with phospholipids. These lipid-like 1,4-DHPs have been earlier proposed as promising nanocarriers for DNA delivery. We have revealed that the mean diameter of freshly prepared nanoparti…

self-assembling propertiessynthetic lipidsDLSpyridinium and propargyl moietiesTEMtoxicity on microorganismscytotoxicitynanoparticlesArticlephospholipid bindingPharmaceutics
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The Spanish Version of the State Self-Compassion Scale–Long Form (SSCS–L): A Study of Its Validity and Reliability in a Sample of Nursing Students

2022

Background: In nurses, self-compassion mitigates the effects of stress, burnout and compassion fatigue, and enhances empathy, compassion and well-being and quality of life. The Self-Compassion Scale is the most-used instrument. The aim of this study is to validate the Spanish version of the new developed State Self-Compassion Scale–Long (SSCS–L). Methods: Students of the first year of the Nursing Degree were surveyed online. Together with the SSCS–L, their levels of positive and negative affect was reported. Analyses included descriptive statistics, competitive confirmatory factor analysis, evidence on criterion-related validity and estimates of reliability. Results: The b…

self-compassion; nursing; validation; burnout; well-beingSurveys and QuestionnairesHealth Toxicology and MutagenesisQuality of LifePublic Health Environmental and Occupational HealthHumansReproducibility of ResultsStudents NursingCompassion FatigueEmpathySelf-CompassionBurnout ProfessionalInternational Journal of Environmental Research and Public Health
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The Time-Varying Effect of Participatory Shift Scheduling on Working Hour Characteristics and Sickness Absence: Evidence from a Quasi-Experiment in H…

2022

Participatory shift scheduling for irregular working hours can influence shift schedules and sickness absence. We investigated the effects of using participatory shift scheduling and shift schedule evaluation tools on working hour characteristics and sickness absence. We utilized a panel data for 2015−2019 with 16,557 hospital employees (6143 in the intervention and 10,345 in the control group). Difference-in-differences regression with ward-level clustered standard errors was used to estimate the average treatment effect on the treated coefficients relative to timing of the intervention with 95% confidence intervals (CI). Using participatory scheduling tool increased long working hou…

self-rosteringworking hourstyöterveystyöhyvinvointiHealth Toxicology and MutagenesisPublic Health Environmental and Occupational Healthsickness absencesairauspoissaolotHospitalsPersonnel Hospitaltyöaikaself-rostering; shift schedule; sickness absence; working hoursosallistaminenvuorotyötyössäkäyntiWork Schedule Tolerancetyöntekijätshift scheduleHumansSick LeavesairauslomaInternational journal of environmental research and public health
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Consensus nomenclature for CD8(+) T cell phenotypes in cancer

2015

International audience; Whereas preclinical investigations and clinical studies have established that CD8+ T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8+ T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8+ T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8+ T cell immunity, leading to the emergence of dysfunctional CD8+ T cells. The existence of different types of CD8+ T…

senescenceT cellOncology and CarcinogenesisImmunology[SDV.CAN]Life Sciences [q-bio]/CancerBiologyCD8+ T cellsIFN gammaanergy03 medical and health sciencesstemness0302 clinical medicineImmune system[SDV.CAN] Life Sciences [q-bio]/Cancerexhaustionmedicine2.1 Biological and endogenous factorsImmunology and AllergyCytotoxic T cellAetiologyPoint of ViewCancer030304 developmental biologyCD8+ T cells; IFNγ; anergy; anticancer immunity; cytotoxicity; effector; exhaustion; senescence; stemness0303 health sciencesTumor microenvironmentCD8(+) T cellsCancermedicine.diseasePhenotype3. Good healthanticancer immunitymedicine.anatomical_structureeffectorOncologyImmunologycytotoxicityCytokine secretionCD8030215 immunologyIFNγ
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Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp. siculum

2012

WOS: 000306752700042

sesquiterpeneeudesmanolidePharmaceutical ScienceFlowersSesquiterpeneArticleChinese hamsterCell LineAnalytical ChemistryHuman lungInhibitory Concentration 50Tanacetumchemistry.chemical_compoundsesquiterpenesDrug DiscoveryBotanymedicineAnimalsHumansCytotoxic T cellSettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryTanacetum vulgarecytotoxic activityCell ProliferationCell DeathbiologyTraditional medicine<em>Tanacetum vulgare</em>; sesquiterpenes; eudesmanolides; cytotoxic activityeudesmanolidesOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationIn vitroTanacetum vulgare; sesquiterpenes; eudesmanolides; cytotoxic activitymedicine.anatomical_structurechemistryPhytochemicalChemistry (miscellaneous)Molecular MedicineColorimetryFormazanMolecules; Volume 17; Issue 7; Pages: 8186-8195
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The Impact of Adolescent Internet Addiction on Sexual Online Victimization: The Mediating Effects of Sexting and Body Self-Esteem

2021

Adolescents’ problematic use of the internet and the risk of sexual online victimization are an increasing concern among families, researchers, professionals and society. This study aimed to analyze the interplay between adolescents’ addiction to social networks and internet, body self-esteem and sexual–erotic risk behavior online: sexting, sextortion and grooming. While sexting refers to the voluntary engagement in texting sexual–erotic messages, sextortion and grooming are means of sexual–erotic victimization through the use of the internet. Participants were 1763 adolescents (51% girls), aged 12 to 16 years (M = 14.56

sextingAdolescentHealth Toxicology and Mutagenesismedia_common.quotation_subjectSexual Behavioreducation050109 social psychologybody self-esteemArticleStructural equation modelingCyberbullyingDevelopmental psychologyAnimalsHumans0501 psychology and cognitive sciencesSocial mediaAssociation (psychology)ChildCrime Victimsmedia_commongroomingInternetGeekbusiness.industryAddiction05 social sciencesRPublic Health Environmental and Occupational HealthSelf-esteemMental healthstructural equation modeling (SEM)humanitiesinternet addictionsextortionAdolescent BehaviorSpainbehavior and behavior mechanismsMedicineThe InternetFemalebusinessPsychologyInternet Addiction Disorder050104 developmental & child psychology
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Development and validation of the Adolescent Sexting Scale (A-SextS) with a Spanish sample

2020

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sextingAdolescentSexual BehaviorHealth Toxicology and Mutagenesislcsh:MedicinePoison controlPilot Projects050109 social psychologyAdolescentsArticleDevelopmental psychology03 medical and health sciences0302 clinical medicine030225 pediatricsInjury preventionValidationEroticaCriterion validityHumansdefinitionPornography0501 psychology and cognitive sciencesadolescentsChildvalidationText MessagingMeasurementOperationalizationlcsh:R05 social sciencesPublic Health Environmental and Occupational HealthHuman factors and ergonomicsSextingDefinitionPsicologíaSexual intercourseAdolescent BehaviorScale (social sciences)measurementPsychology
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Dual action of phosphonate herbicides in plants affected by herbivore—Model study on black bean aphid Aphis fabae rearing on broad bean Vicia faba pl…

2008

Abstract The interactions between plants, herbicides and herbivore insects were studied as an aspect of possible side effect of the using of phosphonate herbicides. The experimental system was composed of phosphonate herbicides, broad bean Vicia faba (L.) plants and black bean aphid Aphis fabae (Scopoli). Two means of herbicide application, namely standard spraying and direct introduction of the herbicide into stem via glass capillary, were examined. The results obtained for N-2-piridylaminomethylene bisphosphonic acid and its derivatives show 10 times higher inhibition of the plant growth if glass capillary mode was used. When plants were infested by aphids 24 h after the use of herbicide,…

side effectHealth Toxicology and MutagenesisOrganophosphonatesHost-Parasite Interactionschemistry.chemical_compoundAnimalsAphis fabaeHerbivorebiologyHerbicidesbusiness.industryfungiPublic Health Environmental and Occupational HealthPest controlfood and beveragesGeneral Medicinephosphonate herbicidesbiology.organism_classificationPollutionPhosphonateVicia fabaVicia fabaAphischemistryOlfactometerAgronomyAphidsGlyphosateBlack bean aphidadditive actionbusinessEcotoxicology and Environmental Safety
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Valorization of Side Stream Products from Sea Cage Fattened Bluefin Tuna (Thunnus thynnus): Production and In Vitro Bioactivity Evaluation of Enriche…

2022

The valorization of side streams from fishery and aquaculture value-chains is a valuable solution to address one of the challenges of the circular economy: turning wastes into profit. Side streams produced after filleting of sea cage fattened bluefin tuna (Thunnus thynnus) were analyzed for proximate composition and fatty acid profile to evaluate the possibility of producing tuna oil (TO) as a valuable source of &omega;-3 polyunsaturated fatty acids (PUFA) and testing its bioactivity in vitro. Ethyl esters of total fatty acids (TFA), obtained from TO, were pre-enriched by urea complexation (PUFA-Ue) and then enriched by short path distillation (SPD) up to almost 85% of the PUFA fraction (PU…

side streamsfood and beveragesbiomarkersPharmaceutical Scienceω-3 fatty acidseye diseasesadipogenesisSAF-1 cell lineSettore AGR/20 - Zoocoltureside streams; ω-3 fatty acids; tuna fish oils; SAF-1 cell line; biomarkers; lipid metabolism; adipogenesislipid metabolismDrug Discoverylipids (amino acids peptides and proteins)Settore BIO/06 - Anatomia Comparata E Citologiahuman activitiesPharmacology Toxicology and Pharmaceutics (miscellaneous)tuna fish oilsMarine Drugs
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