Search results for "Toxication"
showing 10 items of 57 documents
Parenting Mechanisms in Links Between Parents’ and Adolescents’ Alcohol Use Behaviors
2007
Background: Adolescence has been identified as a critical period with regard to the initiation and early escalation of alcohol use. Moreover, research on familial risk and protective processes provides independent support for multiple domains of parental influence on adolescent drinking; including parents' own drinking behaviors, as well as the practices they employ to socialize their children. Despite this prevalence of findings, whether and how these distinct associations are related to one another is still not entirely clear. Methods: The present study used data from 4,731 adolescents and their parents to test the nature of associations between (a) parents' frequencies of alcohol use and…
Circulating MicroRNAs in Extracellular Vesicles as Potential Biomarkers of Alcohol-Induced Neuroinflammation in Adolescence: Gender Differences
2020
Current studies evidence the role of miRNAs in extracellular vesicles (EVs) as key regulators of pathological processes, including neuroinflammation and neurodegeneration. As EVs can cross the blood&ndash
Binge ethanol drinking during adolescence modifies cocaine responses in mice
2016
Binge ethanol drinking is an emerging pattern of excessive consumption among adolescents and young adults. Repeated ethanol intoxication has negative consequences during critical periods of brain development. Therefore, binge ethanol intake represents a vulnerability factor that promotes subsequent manifestations of neuropsychiatric disorders. In this study, we investigated the effects of oral binge ethanol intake during adolescence on the subsequent effects of cocaine in C57BL/6 mice. Firstly, we evaluated the oral ethanol intake of two binge ethanol procedures with different ethanol concentrations (20% v/v versus 30%, v/v). The highest ethanol intake was found in mice exposed to the lowe…
Treatment Compliance in the Long-Term Paranoid Schizophrenia Telemedicine Study
2017
Schizophrenia is a chronic disease with a relatively high relapse rate. Different methods are introduced to improve compliance of the patients treated by psychiatrists; among them, a new and promising attitude is telepsychiatry. The 12-month clinical study of the compliance in paranoid schizophrenia was performed on the group of 199 patients. Every patient in the study was given a smartphone with the preinstalled original telemedicine platform (Telemedicine MoneoPlatform). The telemedicine system recorded every confirmation of the drug intake, and according to that, the compliance was counted as the percent of the doses of medication confirmed in relation to the planned ones. In the first m…
Parental alcohol intoxication and adverse health outcomes among offspring. A 4-year follow up HUNT study among 2399 Norwegian adolescents.
2020
Highlights • Alcohol’s harm to others includes adverse health outcomes in adolescence. • Non-dependent parental heavy drinking increases health harm among adolescents. • Hospital admission was related to exposure to parental alcohol intoxication. • Mental distress was related to exposure to parental alcohol intoxication. • Poor self-rated health was related to exposure to parental alcohol intoxication.
Opioid metabolism and clinical aspects.
2015
Opioids are are commonly used for the management of acute and chronic pain. Opioids have different physicochemical and pharmacokinetic characteristics, which explain the profound changes in the clinical effect in several clinical conditions. Pharmacokinetics influences the opioid response affecting bioavailability, production of metabolites with residual clinical activity, and elimination. Generality of opioid metabolism and clinical implications for specific opioids in different clinical conditions were reviewed to bridge the gap between pharmacokinetics and clinical response. The knowledge of opioid metabolism is essential, particularly for older and complicated patients who receive multi…
A Rare Case of Water Intoxication in Unusual Chiropratic Prescription: A Medico-Legal Analysis Due to Alleged Malpractice.
2021
Introduction. Water intoxication is a well-recognized cause of symptomatic hyponatremia, whose often fatal consequences are described in a wide variety of conditions such as psychiatric disorders, metabolic dysfunctions, child abuse, drug abuse and several medical procedures. The case. We here report a rare case of a 67-year-old woman with severe acute hyponatremia due to an excessive voluntary water intake – 14 litres in two days – following a chiropractic prescription. The patient developed sudden severe symptoms, including water retention, sensory alteration, altered mental status and tonic-clonic seizures. She was thus admitted to the Intensive Care Unit with a diagnosis of coma due to …
DETECTION, ANALYSIS AND PROCESSING OF ACUTE ALCOHOL INTOXICATIONS COLLECTED AT EMERGENCY DEPARTMENT OF THE “GARIBALDI CENTRO” HOSPITAL IN CATANIA
2021
The study we conducted was highlighted the main clinical aspects of voluntary or accidental acute alcohol intoxication. These intoxication were identified over the five-year period between 2015 and 2019, and we evaluated its pharmacological management by statistical analysis of clinical cases detected at the Emergency Department of “Garibaldi Centro” Hospital in Catania. The extrapolated data showed that acute alcohol intoxications are the main reason of access to the Emergency Department (65%) to which drugs (17%), addicted substances (8%), and other substances (caustics, food, gases and vapours, detergents and soaps, benzene and pesticides, 10%). It has been shown that the most commonly u…
Metal and metallothionein content in tissues from wild and farmed Anguilla anguilla at commercial size.
2007
Metallothionein and metal content (Cd, Zn, Hg, Cu, Fe, Pb and Mn) were determined in various organs of commercially available eel (Anguilla anguilla) of similar size obtained from a local farm and from The Albufera Lake in Valencia (Spain). Farmed fish showed statistically significant higher Cd concentrations in liver and kidney whereas wild individuals had higher levels of Pb in blood and Zn in kidney. Significant positive correlations were found between metallothionein and Cd in kidney of farmed eel and between metallothionein and Cu in liver of wild ones.No statistically significant differences were found between the two populations in the concentration of any of the metals analyzed in m…
Use of dietary supplements and anabolic-androgenic steroids among Finnish adolescents in 1991-2005.
2009
Background : The aim of the study was to describe the prevalence, trends and associated factors of dietary supplements (DS) and anabolic-androgenic steroids (AAS) use among Finnish adolescents. Methods: The sample comprised 30 511 adolescents aged 12–18 years, of which 22 519 (74%) answered a questionnaire. We also studied associations between 14 socioeconomic, health and health behavioural variables and DS and AAS use by logistic regression. Results: The proportion of respondents using DS was 45% during the past year and it increased linearly by age. Vitamins (37%) and herbal products (13%) were the most common DSs. In 1991, 9% of the boys aged 16–18 years reported protein use, while the f…