Search results for "Transcranial Magnetic Stimulation"
showing 10 items of 285 documents
From different neurophysiological methods to conflicting pathophysiological views in migraine: a critical review of literature.
2014
Abnormal increased cortical responsivity to various types of stimuli plays a major role in migraine pathogenesis. Neurophysiological studies, however, have provided ambiguous findings of either hypo or hyper cortical excitability. This is why the term "dysexcitability" has been recently proposed to indicate a more general dysregulation of cortical excitability. The aims of this review are: (1) to provide existing knowledge and research advances in migraine pathophysiology; (2) to propose a unitary interpretation of apparently conflicting neurophysiological findings. Data of studies conducted in migraine through various evoked potentials techniques and non-invasive brain stimulation methods …
Motor imagery and cortico-spinal excitability: A review
2016
International audience; Motor imagery (MI) has received a lot of interest during the last decades as its chronic or acute use has demonstrated several effects on improving sport performances or skills. The development of neuroimagery techniques also helped further our understanding of the neural correlates underlying MI. While some authors showed that MI, motor execution and action observation activated similar motor cortical regions, transcranial magnetic stimulation (TMS) studies brought great insights on the role of the primary motor cortex and on the activation of the cortico-spinal pathway during MI. After defining MI and describing the TMS technique, a short report of MI activities on…
Hemispheric Differences in Functional Interactions Between the Dorsal Lateral Prefrontal Cortex and Ipsilateral Motor Cortex
2020
Background: The dorsolateral prefrontal cortex (DLPFC) in both hemispheres have a central integrative function for motor control and behavior. Understanding the hemispheric difference between DLPFC and ipsilateral motor cortex connection in the resting-state will provide fundamental knowledge to explain the different roles DLPFC plays in motor behavior. Purpose: The current study tested the interactions between the ipsilateral DLPFC and the primary motor cortex (M1) in each hemisphere at rest. We hypothesized that left DLPFC has a greater inhibitory effect on the ipsilateral M1 compared to the right DLPFC. Methods: Fourteen right-handed subjects were tested in a dual-coil paired-pulse parad…
Brain stimulation procedures for treatment of contralesional spatial neglect
2011
The application of brain stimulation techniques for modulation of cortical excitability changes underlying spatial neglect following right-brain-damage has been the first application of brain stimulation in the rehabilitation setting. Several factors concur in making neglect a prototype of cognitive disorders that can be modulated by brain stimulation: 1) neglect is highly lateralized deficit, 2) neglect is a network disorder in which lesion of a network node impacts affects excitability of intrahemispehric and interhemispheric connections, and 3) lesions of the right hemisphere, the most frequent cause of neglect, are associated with a transcallosally mediated increase of facilitation of t…
The effect of transient visual deprivation on motor cortical excitability and motor learning : a pilot study
2016
Castro, Fabio, 2015. The Effect of Transient Visual Deprivation on Motor Cortical Excitability and Motor Learning. University of Jyväskylä, Department of Biology of Physical Activity, Master Thesis in Applied Biomechanics. 86 pp. We devised an experimental protocol to test the hypothesis that if the performer poses attention on the proprioceptive signals, in the form of awareness of the body in space, this could increase the corticospinal excitability and the overall performance. 10 right-handed volunteers were randomly assigned to either a group performing a skill training blindfolded (BLIND) or in normal (NORM) condition. The intervention included a visuomotor task-related skill training …
Chapter 31 Transcranial magnetic stimulation studies of contralesional space attention deficits
2002
Publisher Summary The power of transcranial magnetic stimulation (TMS) to disrupt and modulate the neural activity in focal brain regions has provided researchers in this field a promising tool to empirically test specific neuropsychological models and constructs of contralesional space attention deficits. A group of studies has used TMS to transiently disrupt the cortical activity of the focal brain areas in normal subjects to replicate the effects of neurological lesions. This chapter discusses a number of studies, using single-pulse, paired-TMS, and repetitive TMS (rTMS) and different experimental paradigms that show how this technique can be of fundamental importance, in elucidating the…
Transcranial Magnetic Stimulation and Neuroimaging Coregistration
2013
The development of neuroimaging techniques is one of the most impressive advancements in neuroscience. The main reason for the widespread use of these instruments lies in their capacity to provide an accurate description of neural activity during a cognitive process or during rest. This important advancement is related to the possibility to selectively detect changes of neuronal activity in space and time by means of different biological markers. Specifically, functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), and nearinfrared spectroscopy (NIRS) use metabolic markers of ongoing neuronal activity to provide a…
Neurophysiological Changes After Paired Brain and Spinal Cord Stimulation Coupled With Locomotor Training in Human Spinal Cord Injury
2021
Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeated stimulation and locomotor training are not commonly employed in research even though combination of interventions is a common clinical practice. In this randomized clinical trial, we established neurophysiological changes when transcranial magnetic stimulation (TMS) of the motor cortex was paired with transcutaneous thoracolumbar spinal (transspinal) stimulation in human spinal cord injury (SCI) delivered during locomotor training. We hypothesized that TMS delivered before transspinal (TMS-transspinal) stimulation promotes functional reorganization of spinal networks during stepping. In this p…
The effect of paired associative stimulation-induced long-term potentiation-like plasticity on visuomotor learning
2014
Aivojen hermostollisissa rakenteissa ja toiminnassa tapahtuu adaptaatiota motorisen oppimisen seurauksena. Eräs ehdotetuista malleista, johon muutokset voivat perustua on hermoliitoksen voimakkuuden pitkäaikainen tehostuminen eli pitkäkestoinen potentiaa-tio (LTP). Keinotekoisesti LTP:n kaltainen vaikutus voidaan tuottaa parillisella as-sosiatiivisella stimulaatiolla (PAS). Lisäksi tutkimustulokset osoittavat, että PAS voi parantaa tietyn tyyppistä motorista oppimista. Tämän tutkimuksen tarkoituksena on sel-vittää miten PAS:n tuottama LTP:n kaltainen plastisuus vaikuttaa visuomotorisen oppi-misen alkuvaiheeseen. Visuomotorinen oppimistehtävä suoritettiin kolme kertaa PAS:n jälkeen. Oppimist…
Can Oscillatory Alpha-Gamma Phase-Amplitude Coupling be Used to Understand and Enhance TMS Effects?
2019
Recent applications of simultaneous scalp electroencephalography (EEG) and transcranial magnetic stimulation (TMS) suggest that adapting stimulation to underlying brain states may enhance neuroplastic effects of TMS. It is often assumed that longer-lasting effects of TMS on brain function may be mediated by phasic interactions between TMS pulses and endogenous cortical oscillatory dynamics. The mechanisms by which TMS exerts its neuromodulatory effects, however, remain unknown. Here, we discuss evidence concerning the functional effects on synaptic plasticity of oscillatory cross-frequency coupling in cortical networks as a potential framework for understanding the neuromodulatory effects o…