Search results for "Transform"

showing 10 items of 3975 documents

Jokamiehen oikeudesta jokamiehen mahdollisuudeksi

2016

Uudenlaisten pedagogisten mallien pohjalle suunnitellut opintokokonaisuudet lisäävät yliopistojen opintotarjonnan saavutettavuutta ja antavat yksilöille paremmat mahdollisuudet elinikäiseen oppimiseen. Luokanopettajien aikuiskoulutuksessa on käynnissä laaja oppimisympäristöjen kehittymistyö, jossa e-oppimisella on näkyvä sija. Aikuisopiskelijoiden elämäntilanne luo haasteita täysipäiväiselle läsnäololle ja siitä noussut tarve on nähty Luokanopettajien aikuiskoulutuksessa myös mahdollisuutena laajentaa henkilökunnan pedagogista osaamista uudistavien e-oppimiskäytänteiden ja pedagogisten mallien suunnittelijoina, kehittäjinä ja toteuttajina. Luokanopettajien aikuiskoulutuksen 25-vuotinen taiv…

aikuiskoulutustransformational pedagogyluokanopettajatopettajankoulutuskontekstuaalis-pedagoginen oppiminenblended learning study module
researchProduct

Impact de la consommation d'aliments ultra-transformés sur les préférences et habitudes alimentaires

2022

alimentation[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionnutritionenfantsaliments ultra-transformés
researchProduct

Distinctive amino acid residue periodicities in terminal sequences of type III and type I secreted proteins from proteobacteria

2007

AbstractThe Fourier transform (FT) method was applied to specify the distribution of 14 predefined groups of amino acids (64 residues) at both termini of annotated type III and type I secreted proteins from proteobacteria. Type I proteins displayed a higher occurrence of significant periodicities at both C-and N-termini, indicating potent features to discriminate between secretion types, particularly by the use of variables selected from the full periodicity profiles at 19 orders of FT. The Fishers linear discriminant analysis, together with the stepwise selection of variables throughout equal pairs of combinations for all predefined groups of residues, revealed the C-terminal harmonics of …

amino acid periodicityQH301-705.5Computational biologyBiologyBioinformaticsGeneral Biochemistry Genetics and Molecular Biologysymbols.namesakeDiscriminant function analysisprotein secretionBiology (General)chemistry.chemical_classificationGeneral Immunology and MicrobiologyGeneral NeuroscienceStepwise regressiondiscriminant analysisLinear discriminant analysisbiology.organism_classificationAmino acidSecretory proteinFourier transformchemistryTest setsymbolsProteobacteriaGeneral Agricultural and Biological SciencesproteobacteriaOpen Life Sciences
researchProduct

The Future is Now : UAS Language Education in Transition

2019

The current article discusses how the increasing student diversity and transformation of work challenge language education at the Finnish universities of applied sciences (UAS). The article highlights some administrative and pedagogical solutions that have been developed at Karelia UAS to enable the progress of diverse students towards professional competence in foreign languages necessitated by the changes in the labour market. The aim of this article is to evoke discussion on the future directions of language education in vocational higher education. nonPeerReviewed

ammattikorkeakoulutLanguage for Specific Purposesmoninaisuusvieraskielinen opetusComputingMilieux_COMPUTERSANDEDUCATIONstudent diversitydigitalisationintegraatiouniversity of applied sciencestyöelämäContent and Language Integrated Learningdigitalisaatiotransformation of work
researchProduct

Abnormal textures identification based on digital Hilbert optics methods: fundamental transforms and models

2018

The article presents the abnormal textures identification technology based on structural and statistical models of amplitude-phase images (APIm)– multidimensional data arrays (semantic models) and statistical correlation analysis methods using the generalized discrete Hilbert transforms (DHT)– 2D Hilbert (Foucault) isotropic (HTI), anisotropic (HTA) and total transforms – AP-analysis (APA) to calculate the APIm. The identified fragments of textures are obtained as examples of experimental observation of real mammograms contains areas of pathological tissues. The DHT based information technology as conceptual chart description is discussed and illustrated with DHO domain images. As additiona…

amplitude-phase imagesgeneralized Hilbert transformsabnormal textures identification
researchProduct

Tiempos felices: Transformaciones en las tecnologías psicológicas de gobierno de la subjetividad

2020

This paper traces some inflections in the psy disciplines? discourses and technologies for the government of subjectivity during the last decades. It is focused on exploring different mechanisms through which psychological disciplines ?their discourses, techniques and practices? penetrate social life and contribute to establishing subject models consistent with transformations in the political and economic rationalities of late capitalism. Drawing on previous research in the field of gender politics and happiness discourses in the pop psychological culture, I track a line with three moments: i) the production of psychological individuality and identity normalization; ii) the proliferation o…

and iii) the management of affects and the re-timing of bodily propensities Felicidadii) the proliferation of identity categories within the culture of self-empowermentCultura Terapéutica:SOCIOLOGÍA [UNESCO]psychologyPsicologíagovernmentality1137-7038 8537 Arxius de sociologia 562372 2020 42 7674039 Tiempos felices: Transformaciones en las tecnologías psicológicas de gobierno de la subjetividad Martínez Guzmántechniques and practices? penetrate social life and contribute to establishing subject models consistent with transformations in the political and economic rationalities of late capitalism. Drawing on previous research in the field of gender politics and happiness discourses in the pop psychological cultureAntar This paper traces some inflections in the psy disciplines? discourses and technologies for the government of subjectivity during the last decades. It is focused on exploring different mechanisms through which psychological disciplines ?their discoursesUNESCO::SOCIOLOGÍAhappinessTransformaciones en las tecnologías psicológicas de gobierno de la subjetividad Martínez Guzmán [1137-7038 8537 Arxius de sociologia 562372 2020 42 7674039 Tiempos felices]i) the production of psychological individuality and identity normalization [I track a line with three moments]I track a line with three moments: i) the production of psychological individuality and identity normalizationGubernamentalidadtherapeutic culture 159 173
researchProduct

Effect of dual blockade of renin-angiotensin system on TGF beta 1 and left ventricular structure and function in hypertensive patients

2007

The effects of 24 weeks losartan and ramipril treatment,both alone and in combination, on left ventricular mass (LVM), circulating transforming growth factor b1(TGFb1), procollagen type I (PIP) and III (PIIIP), havebeen evaluated in hypertensive (HT) patients. A total of 57 HT with stage 1 and 2 essential hypertension were included. After 4 weeks run in, a randomized double blind, three arms, double dummy, independent trial was used. All HT patients were randomly allocated to three treatment arms consisting of losartan (50 mg/daily),ramipril (5 mg/ daily) and combined (losartan 50 mg/daily plus ramipril 5 mg/daily) for 24 weeks. TGFb1, PIP and PIIIP, LVM, LVM/h 2.7 and other echocardiograph…

angiotensin II receptor blockertransforming growth factor b1left ventricular geometry and functionprocollagen type I and IIIace-inhibitor
researchProduct

Procollagen C-proteinase Enhancer Stimulates Procollagen Processing by Binding to the C-propeptide Region Only*

2011

Background: Procollagen C-proteinase enhancer-1 (PCPE-1) is an extracellular glycoprotein that increases activity of certain zinc metalloproteinases involved in tissue development and repair. Results: PCPE-1 binds uniquely to the C-propeptide region of the procollagen molecule. Conclusion: PCPE-1 enhances proteolysis by binding solely to the procollagen C-propeptides. Significance: These data may lead to future applications in the development of antifibrotic therapies.

animal structuresGlycosylationBiologyBiochemistryBone morphogenetic protein 1Protein Structure SecondaryBone Morphogenetic Protein 103 medical and health scienceschemistry.chemical_compoundMetalloprotease0302 clinical medicineHumansBinding siteEnhancerMolecular Biology030304 developmental biologyCell Line TransformedGlycoproteinschemistry.chemical_classification0303 health sciencesMetalloproteinaseExtracellular Matrix ProteinsBinding Sitesintegumentary systemCell BiologyEnzymatic ProcessingFibrosisExtracellular MatrixProcollagen peptidaseCollagen Type IIIchemistryBiochemistry030220 oncology & carcinogenesisembryonic structuresEnzymologyCollagenGlycoproteinProtein Processing Post-TranslationalTriple helixThe Journal of Biological Chemistry
researchProduct

EFFICIENT SOLUTION OF HETEROGENEOUS ANISOTROPIC DIFFUSION PROBLEMS

2012

anisotropic diffusion heterogeneous medium M-matrix Delaunay mesh affine transformation edge swapSettore ICAR/01 - Idraulica
researchProduct

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

2008

Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …

antisense oligonucleotideCD4-Positive T-LymphocytesAdoptive cell transferT-Lymphocytesanimal cellCell CommunicationInbred C57BLT-Lymphocytes RegulatoryTransgenicMiceregulatory T lymphocyteCrohn DiseaseTransforming Growth Factor betamononuclear cellRAG1 proteinIntestinal MucosaenteritisCells CulturedMice KnockoutSettore MED/12 - GastroenterologiaCulturedintegumentary systemmedicine.diagnostic_testarticleGastroenterologyInterleukinhemic and immune systemsT helper cellColitisRegulatoryUp-Regulationmedicine.anatomical_structurepriority journalgamma interferonSignal TransductionRegulatory T cellColonCellsKnockoutanimal experimentinterleukin 6chemical and pharmacologic phenomenaMice TransgenicBiologyinterleukin 2Recombination-activating geneFlow cytometryProinflammatory cytokineSmad7 ProteinmedicineAnimalsHumanscontrolled studyhumanlamina propriamouseCell ProliferationHomeodomain ProteinsCD4+ T lymphocytenonhumanHepatologyAnimalflow cytometryhuman cellanimal cell culturetransgenic mouseMice Inbred C57BLDisease Models Animalantisense oligonucleotide; gamma interferon; interleukin 17; interleukin 2; interleukin 6; RAG1 protein; Smad7 protein; animal cell; animal cell culture; animal experiment; article; CD4+ T lymphocyte; cell proliferation; colitis; controlled study; enteritis; flow cytometry; human; human cell; knockout mouse; lamina propria; mononuclear cell; mouse; nonhuman; priority journal; regulatory T lymphocyte; transgenic mouse; Animals; CD4-Positive T-Lymphocytes; Cell Communication; Cell Proliferation; Cells Cultured; Colitis; Colon; Crohn Disease; Disease Models Animal; Homeodomain Proteins; Humans; Intestinal Mucosa; Mice; Mice Inbred C57BL; Mice Knockout; Mice Transgenic; Signal Transduction; Smad7 Protein; T-Lymphocytes Regulatory; Transforming Growth Factor beta; Up-RegulationDisease ModelsImmunologyinterleukin 17knockout mouseTransforming growth factorGastroenterology
researchProduct