Search results for "Transformation"
showing 10 items of 1634 documents
The sunset of Gortyn: amphorae in 7th –8th centuries AD
2014
Gortyn (A. Di Vita [ed.] 2000-01), some new contexts, more delimited and reliable, allow us to define better circulation, developments, and local use of amphorae in the last periods of urban life of the Cretan city. Two contexts of the mid-late 7th and late 7th-8th centuries are briefly analysed, coming from different quarters of the town (the Old Agora and the Early Byzantine houses near the “Praetorium”), and resulting from different formative processes, which could represent the circulation trends just before, and in the re-occupation phase after the earthquake that dismembered the Late Roman urban layout at the end of the 7th/early 8th century. They display a variety of imports from tra…
Physics at the grocery store
2022
The motion of a food can on an accelerated conveyor belt in a grocery store is described by means of Newtonian mechanics. By assuming that the food can may roll on the conveyor belt, when the cashier starts this device, one can prove that the rolling motion, observed in the belt reference system, is such that the can is seen to move away for the cashier. Experiments can be performed with common material: an empty and a full food can, and a sheet of paper as conveyor belt.
The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.
2019
1. Preamble : Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) [1]. Increased levels of low density lipoprotein cholesterol (LDL-C) are associated with an increased risk of coronary heart disease (CHD) and many clinical trials have shown that reducing LDL-C levels significantly reduced the CHD and CVD risk [[2], [3], [4], [5]]. Thus LDL-C-lowering is the main approach for the management of cardiovascular disease. Current guidelines suggest LDL-C levels targets based on the individual CV risk; such targets can be achieved by several means, which include both lifestyle changes and pharmacological approaches [6], with statins being the cornerstone …
Influence ofKi-ras-driven oncogenic transformation on the protein network of murine fibroblasts
2007
Ki-ras gene mutations that specifically occur in codons 12, 13 and 61 are involved in the carcinogenesis of acute myeloid leukemia, melanoma and different carcinomas. In order to define potential mutation-specific therapeutic targets, stable transfectants of NIH3T3 cells carrying different Ki-ras4B gene mutations were generated. Wild type Ki-ras transformants, mock transfectants and parental cells served as controls. These in vitro model systems were systematically analyzed for their protein expression pattern using two-dimensional gel electrophoresis followed by mass spectrometry and/or protein sequencing. Using this approach, a number of target molecules that are differentially but coordi…
Towards a Hostessing Society? Mobile Arrangements of Gender and Labour
2008
This article theorizes the forms and interrelations of mobilized work and arrangements of gender in the context of “new work”: an ideology of the flexible labour market of the new economy from the perspective of the workers. The notion of new work is further complicated by the thesis of the feminization of work, whereby, on the one hand, temporary employment is increasingly common also among men and, on the other, attributes and conditions formerly connected to women and understood as feminine virtues or domestic skills are now required from both women and men. Meanwhile, women migrate and are trafficked from poor countries to wealthy ones to perform a range of “old work” for women. Here, t…
Posttranslational N-glycosylation of the hepatitis B virus large envelope protein
2007
Abstract Background The addition of N-linked glycans to proteins is normally a cotranslational process that occurs during translocation of the nascent protein to the endoplasmic reticulum. Here, we report on an exception to this rule occurring on the hepatitis B virus (HBV) large L envelope protein that is a subject to co-plus posttranslational N-glycosylation. Results By using an improved detection system, we identified so far unrecognized, novel isoforms of L. Based on mutational analyses, the use of N-glycosylation inhibitors, and pulse-chase studies, we showed that these isoforms are due to posttranslational N-glycan addition to the asparagines 4 and 112 within the preS domain of L. Whi…
RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours
2019
ObjectiveWe aimed at the identification of genetic alterations that may functionally substitute for CTNNB1 mutation in ß-catenin-activated hepatocellular adenomas (HCAs) and hepatocellular carcinoma (HCC).DesignLarge cohorts of HCA (n=185) and HCC (n=468) were classified using immunohistochemistry. The mutational status of the CTNNB1 gene was determined in ß-catenin-activated HCA (b-HCA) and HCC with at least moderate nuclear CTNNB1 accumulation. Ultra-deep sequencing was used to characterise CTNNB1wild-type and ß-catenin-activated HCA and HCC. Expression profiling of HCA subtypes was performed.ResultsA roof plate-specific spondin 2 (RSPO2) gene rearrangement resulting from a 46.4 kb microd…
Exact results for accepting probabilities of quantum automata
2001
One of the properties of Kondacs-Watrous model of quantum finite automata (QFA) is that the probability of the correct answer for a QFA cannot be amplified arbitrarily. In this paper, we determine the maximum probabilities achieved by QFAs for several languages. In particular, we show that any language that is not recognized by an RFA (reversible finite automaton) can be recognized by a QFA with probability at most 0.7726...
Quality of Service Management on Multimedia Data Transformation into Serial Stories Using Movement Oriented Method
2011
Multimedia data transformation into serial stories or story board will help to reduce the consumption of storage media, indexing, sorting and searching system. Movement Oriented Method that is being developed changes the form of multimedia data into serial stories. Movement Oriented Method depends on the knowledge each actor who uses it. Different knowledge of each actor in the transformation process raises complex issues, such as the sequence, and the resulted story object that could become the standard. And the most fatal could be, the resulted stories does not same with the original multimedia data. To solve it, the Standard Level Knowledge (SLK) in maintaining the quality of the story c…
Modified Operators Interpolating at Endpoints
2021
Some classical operators (e.g., Bernstein) preserve the affine functions and consequently interpolate at the endpoints. Other classical operators (e.g., Bernstein–Durrmeyer) have been modified in order to preserve the affine functions. We propose a simpler modification with the effect that the new operators interpolate at endpoints although they do not preserve the affine functions. We investigate the properties of these modified operators and obtain results concerning iterates and their limits, Voronovskaja-type results and estimates of several differences.