Search results for "Translation"

A Quantitative Analysis of the Romanian Translations of Shakespeare’s Bawdy Puns

2020

This article proposes a quantitative analysis of the Romanian translations of 325 ribald Shakespearean puns, which originate in 20 plays and 71 renditions, with special focus on assessing the impact of translator-subjective and objective factors on the rendition process in the pre-communist, communist, and post-communist periods. The findings invalidate several widespread beliefs: Dragoș Protopopescu’s renditions, banned by the communist regime for their ‘modernizing’ approach to the Shakespearean text, bowdlerized more bawdy puns than ‘ESPLA’, which replaced it as the Party-approved Romanian edition of the dramatist’s plays; Adolphe Stern’s translations, harshly criticized in his period, f…

Facetten der literarischen Übersetzung

2018

Targeted therapy of liver fibrosis/cirrhosis and its complications.

2011

Department of Pharmacokinetics, Toxicology, and Targeting, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands; Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA; Division of Molecular and Translational Medicine, Johannes Gutenberg University, Langenbeckstr. 1, 55131 Mainz, Germany

Anti-fibrotic therapy: lost in translation?

2012

While preclinical development of potential anti-fibrotics is far advanced, with numerous pharmacological targets and promising agents, almost none has entered clinical validation. Reasons are manifold, including the usually slow progression of liver fibrosis, requiring high numbers of well-stratified patients undergoing long-term treatment when conventional liver biopsy based parameters or hard liver-related endpoints are used. Importantly, there is a notorious lack of sensitive and specific surrogate markers or imaging technologies for liver fibrosis progression or regression that would permit a rapid clinical screening for potential anti-fibrotics. Nonetheless, in view of an urgent need f…

Exploring translation strategies in video game localization

2012

This paper addresses the issue of video game localisation focusing on the different strategies to be used from the point of view of Translation Studies. More precisely, the article explores the possible relation between the translation approaches used in the field and the different genres or textual typologies of video games. As the narrative techniques and the story lines of video games have become more complex and well-developed, the adaptation of games entails a serious challenge for translators. Video games have evolved into multimodal and multidimensional products and new approaches and insights are required when studying the adaptation of games into different cultures. Electronic ente…

Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing

2012

We identified syntaxin 5 (Stx5), a protein involved in intracellular vesicle trafficking, as a novel interaction partner of the very low density lipoprotein (VLDL)-receptor (VLDL-R), a member of the LDL-receptor family. In addition, we investigated the effect of Stx5 on VLDL-R maturation, trafficking and processing. Here, we demonstrated mutual association of both proteins using several in vitro approaches. Furthermore, we detected a special maturation phenotype of VLDL-R resulting from Stx5 overexpression. We found that Stx5 prevented advanced Golgi-maturation of VLDL-R, but did not cause accumulation of the immature protein in ER, ER to Golgi compartments, or cis-Golgi ribbon, the main ex…

Highlight on transient activation of red/ox-dependent survival signals involving MEK/ERK and PI3/Akt signaling pathways in 27-hydroxycholesterol trea…

2014

S-nitrosylation of the death receptor fas promotes fas ligand-mediated apoptosis in cancer cells.

2011

International audience; BACKGROUND & AIMS: Fas belongs to the family of tumor necrosis factor receptors which induce apoptosis. Many cancer cells express Fas but do not undergo Fas-mediated apoptosis. Nitric oxide reverses this resistance by increasing levels of Fas at the plasma membrane. We studied the mechanisms by which NO affects Fas function. METHODS: Colon and mammary cancer cell lines were incubated with the NO donor glyceryl trinitrate or lipid A; S-nitrosylation of Fas was monitored using the biotin switch assay. Fas constructs that contained mutations at cysteine residues that prevent S-nitrosylation were used to investigate the involvement of S-nitrosylation in Fas-mediated cell…

Analysing effectiveness of force application in ski skating using force and motion capture data : a model to support cross-country skiing research an…

2014

Maastohiihto on huomattavan vaativaa kokovartaloliikuntaa niin fysiologian kuin biomekaniikankin kannalta tarkasteltuna. Latujen kunnostuksen, hiihtovälineiden, hiihtotekniikoiden sekä kilpailumuotojen kehityksen myötä hiihdosta on tullut nopeampaa ja vaativampaa, joka asettaa suurempia haasteita voimantuotolle. Vastaavasti hiihtotutkimuksessa huomio on viime vuosikymmeninä siirtynyt enemmän biomekaniikan suuntaan. Ensimmäiset ulkoisten suksi- ja sauvavoimien mittaukset suoritettiin yli kolmekymmentä vuotta sitten ja useita yhteyksiä voimantuoton ominaisuuksien ja hiihtosuorituskyvyn välillä on sittemmin tunnistettu. Edelleen on kuitenkin epäselvää mitkä ovat tärkeimmät voimamuuttujat kuvaa…

The First translations of Machiavelli's Prince, Amsterdam - New York, Rodopi, 2010, pp. 329.

2010

Il libro analizza le prime traduzioni del Principe di Machiavelli in Europa.